Time of day as a critical variable in biology DOI Creative Commons
Randy J. Nelson, Jacob R. Bumgarner, Jennifer A. Liu

et al.

BMC Biology, Journal Year: 2022, Volume and Issue: 20(1)

Published: June 15, 2022

Abstract Background Circadian rhythms are important for all aspects of biology; virtually every aspect biological function varies according to time day. Although this is well known, variation across the day also often ignored in design and reporting research. For review, we analyzed top 50 cited papers 10 major domains sciences calendar year 2015. We repeated analysis 2019, hypothesizing that awarding a Nobel Prize 2017 achievements field circadian biology would highlight importance scientists many disciplines, improve time-of-day reporting. Results Our analyses these 1000 empirical papers, however, revealed most failed include sufficient temporal details when describing experimental methods few systematic differences existed between 2015 2019. Overall, only 6.1% reports included information about measures manipulations permit replication. Conclusions defining feature systems, knowing systems evaluated fundamentally information. Failing account hampers reproducibility laboratories, complicates interpretation results, reduces value data based predominantly on nocturnal animals extrapolating diurnal humans.

Language: Английский

Circadian regulation of glucose, lipid, and energy metabolism in humans DOI
Eleonora Poggiogalle, Humaira Jamshed, Courtney M. Peterson

et al.

Metabolism, Journal Year: 2017, Volume and Issue: 84, P. 11 - 27

Published: Dec. 2, 2017

Language: Английский

Citations

495
Meal Timing Regulates the Human Circadian System DOI Creative Commons
Sophie M. T. Wehrens, Skevoulla Christou, C Isherwood

et al.

Current Biology, Journal Year: 2017, Volume and Issue: 27(12), P. 1768 - 1775.e3

Published: June 1, 2017

Language: Английский

Citations

458
The Role of Microbiome in Insomnia, Circadian Disturbance and Depression DOI Creative Commons
Yuanyuan Li, Yanli Hao, Fang Fan

et al.

Frontiers in Psychiatry, Journal Year: 2018, Volume and Issue: 9

Published: Dec. 5, 2018

Good sleep and mood are important for health keeping active. Numerous studies have suggested that the incidence of insomnia depressive disorder linked to biological rhythms, immune function nutrient metabolism, but exact mechanism is not yet clear. There considerable evidence showing gut microbiome only affects digestive, metabolic, functions host also regulates mental states through microbiome-gut-brain axis. Preliminary indicates microorganisms circadian genes can interact with each other. The characteristics gastrointestinal metabolism related host's rhythm. Moreover, emotion physiological stress affect composition microorganisms. inflammation may be loss, misalignment, affective disorders metabolic disease. In this review article, we discuss various how its activities rhythms emotions host. Exploring effects on depression will help further our understanding pathogenesis disorders. It therefore regulate maintain a normal micro-ecological environment in patients when treating

Language: Английский

Citations

234
Mice under Caloric Restriction Self-Impose a Temporal Restriction of Food Intake as Revealed by an Automated Feeder System DOI Creative Commons
Victoria A. Acosta-Rodríguez,

Marleen H. M. de Groot,

Filipa Rijo‐Ferreira

et al.

Cell Metabolism, Journal Year: 2017, Volume and Issue: 26(1), P. 267 - 277.e2

Published: July 1, 2017

Language: Английский

Citations

224
Chronotype: Implications for Epidemiologic Studies on Chrono-Nutrition and Cardiometabolic Health DOI Creative Commons
Suzana Almoosawi, Snieguole Vingeliene, Frédéric Gachon

et al.

Advances in Nutrition, Journal Year: 2018, Volume and Issue: 10(1), P. 30 - 42

Published: Aug. 20, 2018

Chrono-nutrition is an emerging research field in nutritional epidemiology that encompasses 3 dimensions of eating behavior: timing, frequency, and regularity. To date, few studies have investigated how individual's circadian typology, i.e., one's chronotype, affects the association between chrono-nutrition cardiometabolic health. This review sets directions for future by providing a narrative overview recent epidemiologic on its determinants, with dietary intake Limited was found chronotype infants, children, older adults. Moreover, most evidence adolescents adults restricted to cross-sectional surveys longitudinal cohorts simultaneously collecting data intake. There gap concerning chrono-nutrition. Whether modifies diet health outcomes remains be elucidated. In conclusion, further required understand interplay chrono-nutrition, outcomes.

Language: Английский

Citations

175
Working Time Society consensus statements: Evidence-based effects of shift work on physical and mental health DOI Open Access
Cláudia Roberta de Castro Moreno, Elaine Cristina Marqueze, Charli Sargent

et al.

Industrial Health, Journal Year: 2019, Volume and Issue: 57(2), P. 139 - 157

Published: Jan. 1, 2019

Potential effects of shift work on health are probably related to the misalignment between light-dark cycle and human activity-rest cycle. Light exposure at night mediates these effects, including social leads an inversion activity rest, which, in turn, is linked changes behaviours. This article reviews epidemiological evidence association health, possible mechanisms underlying this association. First, from findings meta-analyses systematic published last 10 yr presented. In addition, it reports larger single-occupation studies recent large population-based general workforce. Koch's postulates were used evaluate development disease as a result work. Finally, we discussed limitations multiple pathways that link with specific disorders methodological challenges facing research. We concluded clearest indications being cause given when there substantial body high quality field showing good laboratory supporting causal explanation link.

Language: Английский

Citations

167
Role of chronotype in dietary intake, meal timing, and obesity: a systematic review DOI
Gabriela Pereira Teixeira, Kisian Costa Guimarães,

Ana Gabriela N S Soares

et al.

Nutrition Reviews, Journal Year: 2022, Volume and Issue: 81(1), P. 75 - 90

Published: June 30, 2022

Recent studies show that dietary habits and obesity seem to be influenced by chronotype, which reflects an individual's preference for the timing of sleeping, eating, activity in a 24-hour period.This review aimed analyze association chronotype with habits, namely energy macronutrient intakes, meal timing, eating patterns, as well obesity.PubMed/MEDLINE, LILACS, Google Scholar databases were searched between 2004 2020. Study selection was performed 2 authors independently; disagreements on eligibility articles resolved third author. After assessment 12 060 abstracts, 43 (21 obesity; 13 food consumption, patterns; 9 addressed both behavior) included.A standard form used extract study design, country, number participants, method determination, main findings.Approximately 95% included showed eveningness at least 1 unhealthy habit. Morningness associated regular consumption fresh minimally processed foods. In addition, about 47% higher late types obesity.Late are more likely present such night, skipping breakfast often, processed/ultraprocessed foods, while early have healthy protective predominantly fresh/minimally Intermediate tend pattern health similar than types. Late also weight body mass index or intermediate types.PROSPERO registration no. CRD42021256078.

Language: Английский

Citations

74
Circadian disruption: New clinical perspective of disease pathology and basis for chronotherapeutic intervention DOI
Michael H. Smolensky, Ramón C. Hermida,

Alain Reinberg

et al.

Chronobiology International, Journal Year: 2016, Volume and Issue: 33(8), P. 1101 - 1119

Published: June 16, 2016

Biological processes are organized in time as innate rhythms defined by the period (τ), phase (peak [Φ] and trough time), amplitude (A, peak-trough difference) mean level. The human structure its entirety is comprised of ultradian (τ < 20 h), circadian (20 h > τ 28 h) infradian bioperiodicities. (CTS) beings, which more complicated than lower animals, orchestrated staged a brain central multioscillator system that includes prominent pacemaker - suprachiasmatic nuclei hypothalamus. Additional activities provided pineal hormone melatonin, circulates during nighttime, left right cerebral cortices. Under ordinary circumstances this coordinates Φ driven subservient peripheral cell, tissue organ clock networks. Cyclic environmental, feeding social cues synchronize endogenous 24 clocks rhythms. Accordingly, functions internal environment integrated for maximum biological efficiency, they also synchronized to external ensure optimal performance response challenge. Artificial light at night (ALAN) exposure can alter CTS work, which, like rapid transmeridian displacement air travel, necessitates realignment multitude In 2001, Stevens Rea coined phrase "circadian disruption" (CD) label misalignment induced ALAN shift work (SW) potential pathologic mechanism increased risk cancer other medical conditions. Current concerns relating effects on motivated us renew our long-standing interest possible role CD etiopathology common diseases patient care. A surprisingly large number conditions involve CD: adrenal insufficiency; nocturia; sleep-time non-dipping rising blood pressure patterns (nocturnal hypertension); delayed sleep syndrome, non-24 sleep/wake disorder; recurrent hypersomnia; SW intolerance; delirium; peptic ulcer disease; kidney failure; depression; mania; bipolar Parkinson's Smith-Magenis syndrome; fatal familial insomnia autism spectrum asthma; byssinosis; cancers; hand, foot mouth post-operative state; ICU outcome. Poorly conceived interventions, example nighttime dosing synthetic corticosteroids certain β-antagonists cyclic nocturnal enteral or parenteral nutrition, plus lifestyle habits, including atypical eating times chronic alcohol consumption, be causal CD. Just many proven chronotherapeutic strategies available today manage several these clinical medicine, seems common, yet mostly unrecognized, disease effective interventions remedy it.

Language: Английский

Citations

168
Timing of food intake impacts daily rhythms of human salivary microbiota: a randomized, crossover study DOI Open Access
María Carmen Collado, Phillip A. Engen,

Cristina Bandín

et al.

The FASEB Journal, Journal Year: 2017, Volume and Issue: 32(4), P. 2060 - 2072

Published: Dec. 12, 2017

The composition of the diet (what we eat) has been widely related to microbiota profile. However, whether timing food consumption (when influences in humans is unknown. A randomized, crossover study was performed 10 healthy normal-weight young women test effect intake on human saliva and fecal samples. More specifically, determine eating late alters daily rhythms salivary microbiota, interrogated samples obtained at 4 specific time points over 24 h, achieve a better understanding relationship between metabolic alterations humans. Results revealed significant diurnal diversity bacterial relative abundance (i.e., TM7 Fusobacteria) across both early conditions. importantly, meal affected toward an inverted rhythm conditions, increased number putative proinflammatory taxa, showing saliva. In study, showed for first impact microbiota. Eating main inverts which may have deleterious metabolism host.— Collado, M. C., Engen, P. A., Bandíín, Cabrera-Rubio, R., Voigt, R. M., Green, S. J., Naqib, Keshavarzian, Scheer, F. A. J. L., Garaulet, Timing impacts microbiota: study. FASEB 32, 2060–2072 (2018). www.fasebj.org

Language: Английский

Citations

139
Chrono‐nutrition: From molecular and neuronal mechanisms to human epidemiology and timed feeding patterns DOI Open Access
Alan Flanagan, David A. Bechtold, Gerda K. Pot

et al.

Journal of Neurochemistry, Journal Year: 2020, Volume and Issue: 157(1), P. 53 - 72

Published: Nov. 22, 2020

Abstract The circadian timing system governs daily biological rhythms, synchronising physiology and behaviour to the temporal world. External time cues, including light‐dark cycle of food intake, provide signals for entrainment central, master clock in hypothalamic suprachiasmatic nuclei (SCN), metabolic rhythms peripheral tissues, respectively. Chrono‐nutrition is an emerging field building on relationship between eating patterns, health. Evidence from both animal human research demonstrates adverse consequences disruption. Conversely, a growing body evidence indicates that aligning intake periods day when processes are optimised nutrition may be effective improving Circadian glucose lipid homeostasis, insulin responsiveness sensitivity, energy expenditure, postprandial metabolism, favour patterns characterised by earlier distribution energy. This review details molecular basis clocks, regulation feeding behaviour, meal as entraining signal models. epidemiology humans examined, together with intervention studies investigating effects morning compared evening chrono‐nutrition interventions such time‐restricted feeding. have therapeutic application individuals at‐risk disease convey health benefits within general population. image

Language: Английский

Citations

138