World Journal of Gastroenterology,
Journal Year:
2018,
Volume and Issue:
24(38), P. 4297 - 4303
Published: Oct. 11, 2018
The
etiology
of
digestive
pathologies
such
as
irritable
bowel
syndrome
(IBS),
inflammatory
diseases
(IBD)
and
cancer
is
not
yet
fully
understood.
In
recent
years,
several
studies
have
evidenced
circadian
variations
in
mechanisms
involved
health.
situations
disturbed
rhythms
(chronodisruption)
where
the
central
clock
peripheral
clocks
receive
incoherent
signals,
synchronicity
lost
producing
implications
for
This
lack
coordination
could
alter
tissue
function
cause
long
term
damage
to
organs.
Life
habits
sleep,
physical
exercise,
social
interaction,
feeding
times
are
determinants
stability
integrity
rhythms.
experimental
clinical
consistently
that
alteration
associated
with
development
mainly
linked
dismotility
or
changes
microbiota
composition.
Likewise,
it
seems
reasonable
deep
into
importance
chronodisruption
a
factor
may
participate
IBS,
IBD
cancers.
Moreover,
life
respecting
should
be
promoted
prevention
these
diseases.
Further
will
allow
us
better
understanding
acting
at
molecular
level,
new
therapeutic
targets.
Nutrients,
Journal Year:
2019,
Volume and Issue:
11(12), P. 2862 - 2862
Published: Nov. 22, 2019
The
human
gut
is
inhabited
by
trillions
of
microorganisms
composing
a
dynamic
ecosystem
implicated
in
health
and
disease.
composition
the
microbiota
unique
to
each
individual
tends
remain
relatively
stable
throughout
life,
yet
daily
transient
fluctuations
are
observed.
Diet
key
modifiable
factor
influencing
microbiota,
indicating
potential
for
therapeutic
dietary
strategies
manipulate
microbial
diversity,
composition,
stability.
While
diet
can
induce
shift
these
changes
appear
be
temporary.
Whether
prolonged
permanent
alterations
unknown,
mainly
due
lack
long-term
interventions,
or
follow-ups
short-term
interventions.
It
possible
that
habitual
diets
have
greater
influence
on
than
acute
strategies.
This
review
presents
current
knowledge
around
response
interventions
identifies
major
factors
contribute
diet.
Overall,
further
research
include
microbiome
measures
required
before
clinical
recommendations
made
modulation
health.
European Journal of Neuroscience,
Journal Year:
2018,
Volume and Issue:
51(1), P. 396 - 412
Published: Oct. 25, 2018
Abstract
Shift
work,
defined
as
work
occurring
outside
typical
daytime
working
hours,
is
associated
with
an
increased
risk
of
various
non‐communicable
diseases,
including
diabetes
and
cardiovascular
disease.
Disruption
the
internal
circadian
timing
system
concomitant
sleep
disturbances
thought
to
play
a
critical
role
in
development
these
health
problems.
Indeed,
controlled
laboratory
studies
have
shown
that
short‐term
misalignment
restriction
independently
impair
physiological
processes,
insulin
sensitivity,
energy
expenditure,
immune
function,
blood
pressure
cardiac
modulation
by
autonomous
nervous
system.
If
allowed
persist,
acute
effects
may
lead
cardiometabolic
diseases
long
term.
Here,
we
discuss
evidence
for
contributions
disruption
metabolic
problems
shift
workers.
Improving
understanding
mechanisms
affected
disturbance
will
contribute
implementation
strategies
prevent
or
mitigate
impact
work.
Nutrients,
Journal Year:
2019,
Volume and Issue:
11(11), P. 2624 - 2624
Published: Nov. 1, 2019
(1)
Background:
Eating
is
fundamental
to
survival.
Animals
choose
when
eat
depending
on
food
availability.
The
timing
of
eating
can
synchronize
different
organs
and
tissues
that
are
related
digestion,
absorption,
or
metabolism,
such
as
the
stomach,
gut,
liver,
pancreas,
adipose
tissue.
Studies
performed
in
experimental
animal
models
suggest
intake
a
major
external
synchronizer
peripheral
clocks.
Therefore,
may
be
decisive
fat
accumulation
mobilization
affect
effectiveness
weight
loss
treatments.
(2)
Results:
We
will
review
multiple
studies
about
three
main
meals
day,
breakfast,
lunch
dinner,
its
potential
impact
glucose
tolerance,
obesity-related
factors.
also
delve
into
several
mechanisms
implicated
obesogenic
effect
late.
Conclusion:
Unusual
time
produce
disruption
circadian
system
might
lead
unhealthy
consequences.
Frontiers in Endocrinology,
Journal Year:
2024,
Volume and Issue:
15
Published: March 22, 2024
Meal
timing
emerges
as
a
crucial
factor
influencing
metabolic
health
that
can
be
explained
by
the
tight
interaction
between
endogenous
circadian
clock
and
homeostasis.
Mistimed
food
intake,
such
delayed
or
nighttime
consumption,
leads
to
desynchronization
of
internal
is
associated
with
an
increased
risk
for
obesity
disturbances
type
2
diabetes
cardiovascular
diseases.
Conversely,
meal
aligned
cellular
rhythms
optimize
performance
tissues
organs.
In
this
review,
we
provide
overview
effects
discuss
underlying
mechanisms.
Additionally,
explore
factors
timing,
including
determinants
chronotype
genetics,
well
external
influences
like
social
factors,
cultural
aspects,
work
schedules.
This
review
could
contribute
defining
meal-timing-based
recommendations
public
initiatives
developing
guidelines
effective
lifestyle
modifications
targeting
prevention
treatment
Furthermore,
it
sheds
light
on
must
considered
in
design
future
intervention
trials.
GTPs
(green
tea
polyphenols)
exert
anti-CRC
(colorectal
cancer)
activity.
The
intestinal
microbiota
and
colonization
by
bacteria
of
oral
origin
has
been
implicated
in
colorectal
carcinogenesis.
GT
modulates
the
composition
mouse
gut
harmonious
with
anticancer
Therefore,
effect
green
liquid
(GTL)
consumption
on
microbiome
is
investigated
healthy
volunteers
(n
=
12).