Effect of heat therapy compared with strength training on metabolic profile, heat shock response, inflammation, cardiovascular responses and microbiota in individuals with type 2 diabetes: Study protocol of a randomized trial DOI Creative Commons
Patrícia Martins Bock, Lucas Stahlhöfer Kowalewski, Layane Ramos Ayres

et al.

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: June 29, 2023

Abstract Background : Heat shock response (HSR) is blocked in diabetes, but can be partially restored by resistance training. Some people have difficulties performing physical exercise, therefore, an alternative therapy heat (HT). Interventions capable of modulating HSR, such as exercise and therapy, are candidates therapeutic strategies combined the prevention treatment diabetes. This study aims to evaluate effect training (RT) HT type 2 diabetes mellitus (T2DM) on HbA1c levels, metabolic inflammatory profile, gut microbiota, HSR. Methods: A randomized, double-blind, parallel clinical trial will conducted for 12 weeks. Participants with T2DM randomized into intervention groups Control (C), RT or HT. In control group, participants not receive any intervention. group RT, perform supervised (~60 min) three non-consecutive days week. undertake whole body environmental chamber initially set at 55.0 o C week (60 min). Blood samples collected before after weeks treatment, response, composition fitness, glycemic control, lipid microbiota diversity, markers flow mediated dilation. Discussion: Since HSR decreased individuals we believe that improving may important prevent chronic complications associated T2DM. determine efficacy compared HR when added conventional The multiple effects might contribute lower mortality risk these individuals. Our first weeks, glucose, Moreover, maintain experimental protocol which time necessary obtain changes main parameter HbA1c. Trial registration: NCT05847075. Registered ClinicalTrials.gov, 05/06/23.

Language: Английский

Cytokines as Key Players in Obesity Low Grade Inflammation and Related Complications DOI
Daniel Ejim Uti, Item Justin Atangwho,

Wilson Achu Omang

et al.

Obesity Medicine, Journal Year: 2025, Volume and Issue: unknown, P. 100585 - 100585

Published: Jan. 1, 2025

Language: Английский

Citations

2
Additive impact of diabetes and sarcopenia on all-cause and cardiovascular mortality: A longitudinal nationwide population-based study DOI
Eyun Song, Soon Young Hwang, Minjeong Park

et al.

Metabolism, Journal Year: 2023, Volume and Issue: 148, P. 155678 - 155678

Published: Aug. 21, 2023

Language: Английский

Citations

14
Associations of meeting 24-h movement guidelines and metabolic syndrome in Korean adults during the COVID-19 pandemic DOI

Seung Woo Shin,

Yun Seo Choi, Young Hwa Kang

et al.

Public Health, Journal Year: 2024, Volume and Issue: 227, P. 187 - 193

Published: Jan. 17, 2024

Language: Английский

Citations

4
Association of hypoglycemic events with cognitive impairment in patients with type 2 diabetes mellitus: Protocol for a dose-response meta-analysis DOI Creative Commons
Min Ye,

A. Yuan,

Qi Qi Yang

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(2), P. e0296662 - e0296662

Published: Feb. 2, 2024

Introduction With an incidence rate as high 46%-58%, hypoglycemia is a common complication of glycemic management among those suffering from type 2 diabetes mellitus(T2DM). According to preclinical research, episodes may impair cognition by harming neurons. However, there still controversy regarding the clinical evidence for relationship between hypoglycemic events and likelihood cognitive impairment. Furthermore, little research has been done on dose-response association incidents possibility To address these knowledge gaps, present intends update comprehension risk impairment clarify correlation dose response incorporating most recent investigations. Method analysis This work developed protocol systematic review meta-analysis that will examine, via well-organized assessment several databases, probability Observational studies investigating connection be included. The databases searched are PubMed, Web Science, Chinese Biomedical Literature Database (CBM), Cochrane Library, Embase, China National Knowledge (CNKI), Wan Fang, Science Technology Periodical (VIP), Du Xiu. establishment each database December 2023 included in search. Two researchers independently screen satisfy requirements both inclusion exclusion. A third researcher asked mediate any disputes. methodological caliber assessed utilizing Newcastle-Ottawa Scale (NOS) or Joanna Briggs Institute (JBI) critical appraisal method. regard GRADE, which stands Grading Recommendations, Assessment, Development, Evaluation, quality evaluated. ROBIS Tool used evaluate bias development review. If data accessible, curve employed Stata software. if does not allow such analysis, descriptive performed. Discussion conclusion Hypoglycemic raise impairment, according earlier study relevant explore results this have significant effects decision-making individuals with diabetes, healthcare providers, government policy institutions. Trial registration Prospero number: CRD42023432352 .

Language: Английский

Citations

2
Exercise Interventions for the Prevention and Treatment of Anthracycline-Induced Cardiotoxicity in Women with Breast Cancer: A Systematic Review DOI Creative Commons
Hongmei Li, Haiyun Liu, Boliang Wang

et al.

Journal of Science in Sport and Exercise, Journal Year: 2024, Volume and Issue: unknown

Published: March 8, 2024

Abstract Purpose Anthracyclines have been one of the standard therapies for breast cancer (BC), and dose-related cardiotoxicity is serious side effect. Exercise an effective strategy prevention management BC, endorsed by experts in both exercise oncology. However, there a great deal confusion about effectiveness on anthracycline-induced prescription (i.e., timing, type, intensity) cardiotoxicity, which limits its application clinical settings. The aim this article to review safety BC patients receiving anthracyclines preventing cardiotoxicity. Methods Six electronic databases were searched using terms related exercise, anthracyclines, retrieving randomized controlled trials either Chinese or English. A summary included literature was also provided. Results Of 202 records screened, 10 eligible. total 434 (stage I–IIIC, mean age ranged from 43.5 52.4 years) included. main findings that: (1) Acute (a single bout) moderate-to-vigorous aerobic could prevent NT-proBNP elevation beyond threshold acute myocardial injury; (2) Long-term (> 8 weeks) moderate-to-high intensity (continuous interval) improve maintain left ventricular ejection fraction cardiorespiratory fitness patients. optimal people with remain unclear. Conclusion Moderate-to-vigorous may be non-pharmacological approach mitigate cardiotoxicities induced women BC. remains

Language: Английский

Citations

2
Effectiveness of resistance training in modulating inflammatory biomarkers among Asian patients with sarcopenia: a systematic review and meta-analysis of randomized controlled trials DOI Creative Commons

Jingxian Xue,

Han Xi,

Yan Zheng

et al.

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: May 28, 2024

Given the high incidence of sarcopenia among Asians, it is imperative to identify appropriate intervention methods. The International Clinical Practice Guidelines for Sarcopenia, developed by Conference on Sarcopenia and Frailty Research (ICFSR) task force, recommends resistance training (RT) as a primary treatment managing sarcopenia. Inflammatory biomarkers serve indicators However, there currently insufficient conclusive evidence regarding effectiveness RT in modulating inflammatory biomarker levels Asian participants with

Language: Английский

Citations

2
Low-Intensity Resistance Exercise in Cardiac Rehabilitation: A Narrative Review of Mechanistic Evidence and Clinical Implications DOI Open Access
Julie Jansen, Paul W. Marshall, Jocelyne Benatar

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(23), P. 7338 - 7338

Published: Dec. 2, 2024

Cardiac rehabilitation, a multi-component intervention designed to mitigate the impact of cardiovascular disease, often underutilises low-intensity resistance exercise despite its potential benefits. This narrative review critically examines mechanistic and clinical evidence supporting incorporation into cardiac rehabilitation programmes. Research indicates that induces hypertrophic adaptations by maximising muscle fibre activation through size principle, effectively recruiting larger motor units as it approaches maximal effort. promotes adaptation in both type I II fibres, resulting comparable increases myofibrillar protein synthesis phosphorylation key signalling proteins when compared high-intensity exercise. Low-intensity provides equivalent improvements muscular strength hypertrophy protocols while addressing barriers participation, such concerns about safety logistical challenges. By facilitating engagement more accessible modality, might improve adherence rates patient outcomes rehabilitation. Additionally, ability address sarcopenia frailty syndrome, significant determinants disease progression, can enhance recovery overall quality life for patients. establishes evidence-based recommendations inclusion offering promising pathway effectiveness these

Language: Английский

Citations

2
Effect of exercise on inflammatory markers in postmenopausal women with overweight and obesity: A systematic review and meta-analysis DOI Creative Commons
Liang Tan, Weihua Yan, Weilin Yang

et al.

Experimental Gerontology, Journal Year: 2023, Volume and Issue: 183, P. 112310 - 112310

Published: Oct. 20, 2023

Postmenopausal women affected by overweight and obesity are susceptible to a variety of diseases due inflammation. Exercise may reduce the risk disease attenuating low-grade chronic

Language: Английский

Citations

6
Genetic predisposition, lifestyle inflammation score, food-based dietary inflammatory index, and the risk for incident diabetes: Findings from the KoGES data DOI
Hye Ah Lee, Hyesook Park, Bomi Park

et al.

Nutrition Metabolism and Cardiovascular Diseases, Journal Year: 2023, Volume and Issue: 34(3), P. 642 - 650

Published: Oct. 29, 2023

Language: Английский

Citations

3
“Does Physical Exercise Promote Health Benefits for Diabetic Patients during the COVID-19 Pandemic?”: A Systematic Review DOI Creative Commons
Erivaldo de Souza, Daniela Meneses Santos,

JOSUÉ CRUZ DOS SANTOS

et al.

Sports, Journal Year: 2023, Volume and Issue: 11(10), P. 192 - 192

Published: Oct. 3, 2023

Patients affected by COVID-19 are prone to facing disorders in multiple systems and organs, which can lead deleterious diseases; addition, people with pre-existing diseases may be more the worst outcomes, most vulnerable patients type 1 2 diabetes mellitus. The aim of this systematic review was evaluate effects physical activity and/or exercise prescribed individuals on maintenance plasma glucose glycated hemoglobin during pandemic. Studies were found searching PubMed, SCOPUS, Embase, Web Science, SciELO, LILACS, SportDiscus, Bireme/BVS Google Scholar databases. inclusion criteria articles that addressed only or (T1D T2D) who had evaluated level described cross-sectional, retrospective, observational studies, meeting main established GRADE. PICO GRADE strategies used select assess methodological quality studies. Two reviewers searched selected databases independently blindly, oppositions disagreements about discussed resolved a third reviewer. Evidence corroborates levels reduced due lockdown, leading increased body weight worse glycemic control. On other hand, mellitus (DM) maintained showed (HbA1c) levels. Adequate beneficial for HbA1c control diabetic (type 2). In maintaining adequate contribute reducing health problems when these infected COVID-19.

Language: Английский

Citations

2