Microbiota in vaginal health and pathogenesis of recurrent vulvovaginal infections: a critical review

Annals of Clinical Microbiology and Antimicrobials, Journal Year: 2020, Volume and Issue: 19(1)

Published: Jan. 28, 2020

Abstract Recurrent vulvovaginal infections (RVVI) has not only become an epidemiological and clinical problem but also include large social psychological consequences. Understanding the mechanisms of both commensalism pathogenesis are necessary for development efficient diagnosis treatment strategies these enigmatic vaginal infections. Through this review, attempt been made to analyze microbiota (VMB) from scratch provide update on its current understanding in relation health common RVVI i.e. bacterial vaginosis, candidiaisis Trichomoniasis, making present review first kind. For this, potentially relevant studies were retrieved data sources critical analysis literature was made. Though, culture-independent methods have greatly unfolded mystery regarding microbiome, there a few composition diversity mycobiome different Trichomonas vaginalis strains. This scenario suggests need further based comparative genomics pathogens improve our perceptive that is still clear (Fig. 5). Besides details rationale Lactobacilli dominance changes occur healthy VMB throughout women’s life. Moreover, list possible agents continues expand new species recognised VVI updated review. The concludes with controversies challenging widely accepted dogma “VMB dominated healthier than diverse VMB”. These controversies, over past decade, complicated definition no definite conclusion. Thus, newly microbial may reveal answers controversies. Conversely, women could be answer it enough just look at microbiology. We woman itself, as which fine one troublesome others. differences response same determined by permutation behavioural, cultural, genetic various other anonymous factors, exploration lead proper disease.

Language: Английский

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Candida albicans Morphogenesis Programs Control the Balance between Gut Commensalism and Invasive Infection

Cell Host & Microbe, Journal Year: 2019, Volume and Issue: 25(3), P. 432 - 443.e6

Published: March 1, 2019

Language: Английский

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Candidemia and Invasive Candidiasis

Infectious Disease Clinics of North America, Journal Year: 2021, Volume and Issue: 35(2), P. 389 - 413

Published: May 18, 2021

Language: Английский

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Advances in Research on the Bioactivity of Alginate Oligosaccharides

Marine Drugs, Journal Year: 2020, Volume and Issue: 18(3), P. 144 - 144

Published: Feb. 28, 2020

Alginate is a natural polysaccharide present in various marine brown seaweeds. oligosaccharide (AOS) degradation product of alginate, which has received increasing attention due to its low molecular weight and promising biological activity. The wide-ranging activity AOS closely related the diversity their structures. with specific structure distinct applications can be obtained by different methods alginate degradation. This review focuses on recent advances derivatives, including anti-tumor, anti-oxidative, immunoregulatory, anti-inflammatory, neuroprotective, antibacterial, hypolipidemic, antihypertensive, hypoglycemic properties, as well ability suppress obesity promote cell proliferation regulate plant growth. We hope that this will provide theoretical basis inspiration for high-value research developments utilization AOS-related products.

Language: Английский

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Multifunctional antimicrobial materials: From rational design to biomedical applications

Progress in Materials Science, Journal Year: 2021, Volume and Issue: 125, P. 100887 - 100887

Published: Nov. 11, 2021

Language: Английский

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