Neuropsychiatric Disease and Treatment,
Journal Year:
2024,
Volume and Issue:
Volume 20, P. 1079 - 1095
Published: May 1, 2024
Background:
University
students
are
a
vulnerable
population
prone
to
mental
health
challenges.
This
study
aimed
investigate
depression
and
its
associated
factors
among
university
in
terms
of
demographics,
eating
habits,
exercises.
Methods:
A
total
2891
from
three
universities
participated
this
between
January
2024
February
2024.
An
online
survey
questionnaire
was
distributed
using
snow-ball
strategy.
The
collected
demographic,
lifestyle,
psychological
data,
including
anxiety
scores
the
PHQ-9
GAD-7
screening
tools.
Subgroup
analysis
conducted
according
sport
frequency
type
Chi-square
test
for
qualitative
data
t
-test
quantitative
data.
Multiple
linear
regression
performed
identify
risk
depression.
Results:
44.2%
39.5%
participants
reported
symptoms
anxiety,
respectively.
Significant
differences
were
observed
various
characteristics
across
different
groups,
with
higher
tending
have
less
(P<
0.001)
symptoms.
As
weekly
exercise
increased,
gradually
decreased.
mean
highest
group
no
sports
lowest
3–
4
times
per
week
0.001).
Additionally,
once
reached
5
or
more,
longer
based
on
revealed
that
engaging
specific
sports,
such
as
basketball,
tennis,
dance,
running,
had
lower
compared
overall
average.
Based
multiple
analysis,
married
status
(P=0.036),
enjoying
barbecue
food
0.001),
prolonged
sedentary
time
(P=0.001),
experiencing
stress
events
electronic
device
usage
positively
scores,
while
loving
vegetables
(P=0.007),
relatively
(P=0.005),
(P=0.064),
chronic
disease
negatively
scores.
Conclusion:
highlights
importance
healthy
regular
exercise,
limited
exposure
screens,
balanced
diet,
preventing
mitigating
students.
also
suggests
exercising
is
levels
Activities
running
effective
alleviating
these
issues
through
exercise.
Keywords:
depression,
students,
cross-sectional
Neuropsychiatric Disease and Treatment,
Journal Year:
2025,
Volume and Issue:
Volume 21, P. 791 - 798
Published: April 1, 2025
Adolescent
MDD
has
become
a
significant
public
health
issue,
yet
its
underlying
mechanisms
remain
unclear.
Multimodal
brain
imaging
techniques
offer
powerful
method
for
exploring
complex
mental
disorders.
However,
evidence
focusing
on
the
multimodal
networks
and
structural-functional
coupling
in
adolescent
depression
is
still
limited.
Participants
with
major
depressive
disorder
(MDD)
were
Han
Chinese
individuals
aged
13
to
18
who
had
been
unmedicated
at
least
two
weeks.
We
conducted
MRI
acquisitions,
including
structural
(sMRI),
resting-state
functional
(rsfMRI),
Diffusion
Tensor
Imaging
(DTI).
The
cortex
was
parceled
into
360
regions
using
HCP-MMP
atlas.
Functional
connectivity
deterministic
matrices
constructed,
coefficients
calculated.
Differences
between
healthy
controls
(HCs)
groups
identified.
A
total
of
25
adolescents
(mean
age:
15.68
years,
standard
deviation
[SD]:
1.18;
Female:
21
(84.00%))
27
hCs
14.30
1.51;
(48.15%))
included
analysis.
There
9
connections
122
that
differed
groups,
involving
multiple
cortical
regions.
Additionally,
we
identified
differences
three
areas,
specifically
posterior
cingulate
ventral
visual
cortex.
involves
disruptions
networks,
coupling.
These
differing
indicators
may
serve
as
potential
biomarkers
MDD.
Neuropsychiatric Disease and Treatment,
Journal Year:
2024,
Volume and Issue:
Volume 20, P. 1377 - 1386
Published: July 1, 2024
Inflammatory
arthritis
refers
to
a
group
of
diseases
that
have
common
presentation
joint
pain,
stiffness,
and
inflammation.
Meanwhile,
major
depressive
disorder
is
mental
health
characterized
by
anhedonia
low
mood.
patients
high
rates
disorder,
estimated
at
being
up
38.8%.
Depression
leads
significant
reduction
in
patient's
health-related
quality
life,
treatment
adherence,
many
other
measures
health,
both
subjective
clinical.
Progress in Neuro-Psychopharmacology and Biological Psychiatry,
Journal Year:
2024,
Volume and Issue:
135, P. 111095 - 111095
Published: July 18, 2024
Unipolar
treatment-resistant
depression
(MDD-TRD)
is
associated
with
neurocognitive
impairment.
Ketamine,
an
emerging
treatment
for
MDD-TRD,
may
have
benefits,
but
evidence
remains
limited.
Journal of Affective Disorders,
Journal Year:
2024,
Volume and Issue:
367, P. 109 - 117
Published: Aug. 24, 2024
Repetitive
transcranial
magnetic
stimulation
(rTMS)
is
an
effective
treatment
in
major
depressive
disorder
(MDD).
However,
intermittent
theta-burst
(iTBS)
and
rTMS
protocols
using
10
Hz
frequency
might
differ
their
effect
on
neuroplasticity
clinical
symptoms.
This
study
compares
the
of
iTBS
a
novel
Hz-rTMS
with
shortened
single
session
duration,
motor
excitability
symptoms
MDD.
Journal of Affective Disorders,
Journal Year:
2024,
Volume and Issue:
356, P. 80 - 87
Published: April 2, 2024
Systemic
low-grade
inflammation
may
be
a
pathophysiological
mechanism
in
subtype
of
depression.
In
this
study
we
investigate
novel
candidate
inflammatory
depression
-
Selective
Glomerular
Hypofiltration
Syndromes
(SGHS)
which
are
characterized
by
reduced
estimated
glomerular
filtration
rate
(eGFR)
based
on
cystatin
C
(cysC)
relative
to
eGFR
creatinine
(crea).
SGHS
have
been
associated
with
increased
blood
levels
pro-inflammatory
markers,
but
never
investigated
sample
depressed
individuals.
Neuropsychiatric Disease and Treatment,
Journal Year:
2024,
Volume and Issue:
Volume 20, P. 1041 - 1048
Published: May 1, 2024
Purpose:
To
determine
whether
perioperative
esketamine
use
decreases
the
risk
of
postpartum
depression
(PPD).
Methods:
Online
search
PubMed,
Web
Science,
and
Embase
was
conducted
to
identify
relevant
studies.
Key
words
for
included,
but
were
not
limited
to,
depression,
esketamine,
clinical
trials.
The
mean
standard
deviation
Edinburgh
Postnatal
Depression
Scale
(EPDS)
scores
extracted
from
studies
as
primary
parameters.
Results:
literature
identified
226
articles,
which
5
met
criteria
enrolled
in
study.
In
total,
886
patients
taken
into
analysis.
EPDS
group
lower
than
those
control
at
early
stage
puerperium
(WMD=−
2.05,
95%
CI:
−
3.77,
0.34,
p
=0.019),
whereas
there
no
significant
difference
middle
later
stages
1.41,
2.86,
0.04,
=0.056).
sensitivity
analyses
indicated
that
result
stable,
it
unreliable
stages.
results
Egger's
test
publication
bias.
Conclusion:
Perioperative
contributes
a
PPD
further
verify
this
conclusion,
more
high-quality
are
required.
Keywords:
pregnant
women,
mental
health