Effects of PM 2.5 exposure on metabolic dysfunction during pregnancy via personalized measurement of pollutant concentration in South Korea: A multicenter prospective cohort, air pollution on pregnancy outcome (APPO) study DOI Creative Commons
Y. Jeong, Sunwha Park, Eunjin Kwon

et al.

Research Square (Research Square), Journal Year: 2022, Volume and Issue: unknown

Published: Nov. 16, 2022

Abstract Background Ambient particulate matter (PM) is a trigger factor for metabolic dysfunction. This study aimed to evaluate the associations between PM exposure and dysfunction in pregnancy. Methods prospective, multicentre, observational, cohort was conducted from January 2021 June 2022. A total of 333 women with singleton pregnancies were recruited. For individual measurement 2.5 levels, an AirguardK ® installed inside participants’ houses. Time-activity logs recorded predict each participant’s personal . The participants divided into groups according concentration calculated by time-weighted average model. We used Student t-test chi-squared test (or Fisher’s exact test) changes compound blood pressure (BP), glucose intolerance, lipid profiles, including serum triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratios. Logistic linear regression models analyse association dysfunction, using odds ratios (ORs) 95% confidence intervals (CIs). Results during pregnancy worsened Third trimester BP elevated those exposed higher levels (p <0.05). incidence gestational diabetes mellitus (GDM) constantly more , regardless cut-off level (PM ≥10 µg/m 3 7.91 % vs. 16.09 %, p <0.05; ≥25 26.67 proportion TG/HDL-C ratio ≥3.0 significantly when (75.3 83.0 Triglyceride group (p=0.0171). found increased risk (adjusted OR [aOR]: 2.228, CI: 1.115–4.449) GDM (aOR 2.263, CI 1.106–5.039) third after adjusting confounders. Conclusion Exposure worsens Further studies are required investigate mechanisms which ambient affects

Language: Английский

Fetal Alcohol Spectrum Disorders DOI
Virginia Leonor Herbas Pacheco, P.A. Márquez Aguilar,

Ana María Arias

et al.

Published: Jan. 1, 2024

Language: Английский

Citations

8
Agenesis of the corpus callosum: What to tell expecting parents? DOI Creative Commons
Pascale Tsai, Shiri Shinar

Prenatal Diagnosis, Journal Year: 2023, Volume and Issue: 43(12), P. 1527 - 1535

Published: Oct. 4, 2023

Abstract Agenesis of the corpus callosum (ACC) is one most common brain malformations, with an incidence estimated to range from 0.5 70 in 10,000 among general population. Prenatal diagnosis made via ultrasound; however, fetal MRI useful confirm or exclude presence associated cerebral abnormalities–mostly cortical malformations–that may affect postnatal prognosis. When no additional central nervous system (CNS) extra CNS anomalies are identified and genetic cause found, isolated ACC diagnosed. Overall, cases ACC, underlying can be up 12.5% chromosomal microarray (CMA) 47% whole exome sequencing (WES). In where only anomaly detected, yield WES 30%. Postnatal outcomes variable depend on whether condition not. truly normal 65% through mild severe neurodevelopmental impairments 35% cases. An interdisciplinary team medical experts key guiding parents toward informed decision‐making pregnancies complicated by ACC. Considering current expected advancements testing imaging technologies upcoming years, we herein summarize recommendations for management prenatal counseling expecting fetuses Our review pertains primarily complete

Language: Английский

Citations

10
Personal exposure of PM2.5 and metabolic syndrome markers of pregnant women in South Korea: APPO study DOI Creative Commons
Y. Jeong, Sunwha Park, Eunjin Kwon

et al.

Environmental Science and Pollution Research, Journal Year: 2023, Volume and Issue: 30(59), P. 123893 - 123906

Published: Nov. 23, 2023

We examined the association between exposure to PM2.5, focused on individual level, and metabolic dysfunction during pregnancy. APPO study (Air Pollution Pregnancy Outcome) was a prospective, multicenter, observational cohort conducted from January 2021 March 2023. Individual PM2.5 concentrations were calculated using time-weighted average model. Metabolic pregnancy assessed based modified definition of syndrome its components, accounting for pregnancy-specific criteria. Exposure associated with worsened parameters especially glucose metabolism. In comparison participants exposed low group, those high levels exhibited increased odds gestational diabetes mellitus (GDM) after adjusting confounding variables in different adjusted models. Specifically, model 1, ratio (aOR) 3.117 95% confidence interval (CI) 1.234-7.870; 2, aOR 3.855 CI 1.255-11.844; 3, 3.404 1.206-9.607; 4, 2.741 0.712-10.547. higher tendency worsen markers specifically homeostasis. Further research is needed investigate mechanisms underlying effects ambient

Language: Английский

Citations

2
Fetal Alcohol Syndrome: a complex case of teratogenic effects of maternal alcohol consumption and clinical managment DOI Creative Commons
Sylwia Koziej, Emilia Kowalczyk, J Borkowska

et al.

Quality in Sport, Journal Year: 2024, Volume and Issue: 15, P. 52107 - 52107

Published: July 6, 2024

Introduction and purpose Maternal alcohol consumption during pregnancy is a well-documented risk factor for adverse fetal outcomes, encompassing spectrum of disorders known as Fetal Alcohol Spectrum Disorders (FASD). Syndrome (FAS), the most severe form FASD, manifests with craniofacial anomalies, growth retardation, neurological deficits, cognitive impairments, imposing lifelong challenges on affected individuals. This article presents case report 4-week-old female newborn suspected Syndrome, highlighting clinical complexities diagnostic associated FAS. The infant exhibited characteristic dysmorphic features cardiac abnormalities, underscoring diverse health issues linked to maternal consumption. Conclusion A presented illustrating FAS underscores importance early recognition multidisciplinary management. Early identification imperative mitigate long-term emphasizing holistic approach care. Strategies addressing include targeted education, preconception counseling, innovative therapeutic modalities. need ongoing research collaborative efforts reduce prevalence impact FASD individuals society.

Language: Английский

Citations

0
Quality of Prenatal Care Among Mothers in Selected Barangays in Davao City, Philippines DOI

Regel Ivan Kent Matutino,

Mohammed Bien Kulintang,

Christian Joy Salas

et al.

Journal of interdisciplinary perspectives, Journal Year: 2024, Volume and Issue: 2(11)

Published: Jan. 1, 2024

Prenatal care encompasses medical attention provided to pregnant women from conception childbirth. This study aimed determine the association between respondents' sociodemographic profiles and quality of prenatal care. A descriptive, correlational research method was used in this study. Utilizing "a priori power analysis," 120 respondents were randomly selected using following criteria: mothers who had checkups barangay health centers a District Davao City, legal age, willing participate study, after giving birth one three months. Data collected March April 2024. Results revealed that most young adult, primigravida, multiparous, with full-term babies, high school graduates, family monthly income 7,000 – 10,000. The high, particularly "information sharing," anticipatory guidance, sufficient time, approachability, availability, support respect. Furthermore, educational attainment, undergraduates, baccalaureate degree holders, term noted have statistically significant their Hence, having good attainment "term baby" reciprocates among respondents. upholds standards services approaches participants experience during checkups.

Language: Английский

Citations

0
The effect of fetal alcohol syndrome on the mental and physical development of a preschool child: a clinical case DOI Creative Commons
A. Yu. Marianian, Е. В. Молчанова, Anastasia M. Molchanova

et al.

GYNECOLOGY, Journal Year: 2023, Volume and Issue: 25(2), P. 267 - 272

Published: July 14, 2023

The article describes a clinical case demonstrating the effect of fetal alcohol syndrome on preschool child's development, challenging diagnosis this disorder, often leading to irreversible congenital mental and physical defects. is because doctors are unaware mother's consumption during pregnancy. Doctors may suspect that child has Fetal syndrome, according presence facial dysmorphism state health mother (pronounced signs dependence). manifestations adverse effects development described in indicate need organize early comprehensive habilitation.

Language: Английский

Citations

0
Effects of PM 2.5 exposure on metabolic dysfunction during pregnancy via personalized measurement of pollutant concentration in South Korea: A multicenter prospective cohort, air pollution on pregnancy outcome (APPO) study DOI Creative Commons
Y. Jeong, Sunwha Park, Eunjin Kwon

et al.

Research Square (Research Square), Journal Year: 2022, Volume and Issue: unknown

Published: Nov. 16, 2022

Abstract Background Ambient particulate matter (PM) is a trigger factor for metabolic dysfunction. This study aimed to evaluate the associations between PM exposure and dysfunction in pregnancy. Methods prospective, multicentre, observational, cohort was conducted from January 2021 June 2022. A total of 333 women with singleton pregnancies were recruited. For individual measurement 2.5 levels, an AirguardK ® installed inside participants’ houses. Time-activity logs recorded predict each participant’s personal . The participants divided into groups according concentration calculated by time-weighted average model. We used Student t-test chi-squared test (or Fisher’s exact test) changes compound blood pressure (BP), glucose intolerance, lipid profiles, including serum triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratios. Logistic linear regression models analyse association dysfunction, using odds ratios (ORs) 95% confidence intervals (CIs). Results during pregnancy worsened Third trimester BP elevated those exposed higher levels (p <0.05). incidence gestational diabetes mellitus (GDM) constantly more , regardless cut-off level (PM ≥10 µg/m 3 7.91 % vs. 16.09 %, p <0.05; ≥25 26.67 proportion TG/HDL-C ratio ≥3.0 significantly when (75.3 83.0 Triglyceride group (p=0.0171). found increased risk (adjusted OR [aOR]: 2.228, CI: 1.115–4.449) GDM (aOR 2.263, CI 1.106–5.039) third after adjusting confounders. Conclusion Exposure worsens Further studies are required investigate mechanisms which ambient affects

Language: Английский

Citations

0