Coffee or tea: Anti-inflammatory properties in the context of atherosclerotic cardiovascular disease prevention

Pharmacological Research, Journal Year: 2022, Volume and Issue: 187, P. 106596 - 106596

Published: Dec. 5, 2022

Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of premature death worldwide. Inflammation and its biomarkers, like C-reactive protein (CRP), among risk factors, such as hypertension, lipid disorders, diabetes, may be also responsible for residual (CVD) risk. Modern lipid-lowering treatment with statins, ezetimibe, PCSK9 inhibitors, or bempedoic acid does not fully protect against inflammation. The recommendations International Lipid Expert Panel (ILEP) indicate selected nutraceuticals anti-inflammatory properties. Diet have a significant impact on Especially interesting in context inflammation consumption coffee tea. These drinks many observational studies significantly reduced mortality. question whether effects these contribute to observed clinical effects. Thus, this narrative review, we primarily discuss properties consuming tea coffee. Based comprehensive analysis their meta-analyses, inconsistent results were obtained, which makes it impossible conclusively state how clinically potential black green are. A number confounding factors can inconsistency available results. Consumption appears increase adiponectin concentrations, decrease reactive oxygen species, low density lipoprotein (LDL) cholesterol concentrations (effect tea, etc.). Despite still uncertain effect coffee, recommend part healthy diet.

Language: Английский

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Sex Related Differences in the Complex Relationship between Coffee, Caffeine and Atrial Fibrillation

Nutrients, Journal Year: 2023, Volume and Issue: 15(15), P. 3299 - 3299

Published: July 25, 2023

This literature review aims to explore the data of articles published on association between coffee, caffeine and atrial fibrillation analyze any differences two sexes. Several factors influence this complex relationship; genetic, environmental psychosocial come into play in pathophysiology fibrillation. These are expressed differently women men. However, analysis has shown that comparison works sexes extremely rare. Most population-based prospective studies either aggregated or focus exclusively male female populations. results a lack information could be useful prevention treatment approach It is necessary deepen issue with dedicated studies.

Language: Английский

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Coffee consumption and mortality in colorectal cancer patients: does the co-existence of cardiometabolic disease matter?

Clinical Nutrition ESPEN, Journal Year: 2025, Volume and Issue: 67, P. 62 - 70

Published: March 6, 2025

Although coffee consumption may have a U-shaped nonlinear relationship with all-cause mortality in colorectal cancer (CRC) patients, it is unclear whether this association could differ the presence of prevalent cardiometabolic disease (CMD). Therefore, we assessed CRC patients stratified by CMD status at diagnosis. We used data from prospective cohort 1769 stage I-III CRC. Coffee was self-reported using food frequency questionnaire Mortality were retrieved Personal Records Database. defined as cardiovascular (CVD) or diabetes diagnosis estimated hazard ratios (HR) and 95 % confidence intervals (CI) Cox proportional hazards models without restricted cubic splines (RCS) while adjusting for relevant confounders. During median (quartile1, quartile 3) follow-up 7.7 (5.6, 9.3) years, observed 128 deaths participants 250 those CMD. The five-year survival rate 88 83 CMD, respectively. Among consuming 2-4 cups/d >4 compared to <2 associated 60 (HR: 0.40, CI: 0.26-0.63) 41 0.59, 0.39-0.89) lower risk mortality, In 31 0.69, 0.51-0.93) no (HR:0.82, 95%CI:0.59-1.14). RCS showed U-shaped, inverse between (P-value nonlinearity: 0.001), but stronger regardless their status. More mechanistic studies are needed understand how patients.

Language: Английский

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Alcohol consumption and atrial fibrillation risk: An updated dose-response meta-analysis of over 10 million participants

Frontiers in Cardiovascular Medicine, Journal Year: 2022, Volume and Issue: 9

Published: Sept. 30, 2022

The treatment of atrial fibrillation (AF) has made significant progress, but the prevention AF not received attention it deserves. A few recent large-sized studies have conducted dose response analysis and reported different conclusions from previous on alcohol consumption risk.The aim this study is to examine potential non-linear association between risk explore differences gender.In updated dose-response meta-analysis, PubMed, Embase Cochrane databases were searched until June 2022. Risk estimates as relative (RR) with 95% confidence intervals (CIs). random-effects restricted cubic spline models are used evaluate risk.A total 10,151,366 participants 214,365 cases enrolled in 13 prospective studies. overall meta-analysis showed that a 1 drink/day increase increased by 6% (RR: 1.06; CI: 1.03-1.08). In gender subgroup analysis, pooled results men 1.08; 1.05-1.11) women 1.05; 0.96-1.14). linear relationship was found (p = 0.87) while J-shaped curve observed 0.00). Regional yielded broadly comparable Americas 1.07; 1.03-1.12), Europe 1.04; 0.99-1.1) Asia 0.99-1.14).The men, shown women.We fibrillation. We merged data over 10 million pattern consumption. women. summary, research vital furthering our understanding role new-onset AF, especially among genders.

Language: Английский

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Alcohol and Atrial Fibrillation

Reviews in Cardiovascular Medicine, Journal Year: 2023, Volume and Issue: 24(3), P. 73 - 73

Published: March 1, 2023

Dietary habits, including alcohol consumption, are among the significant risk factors for occurrence of atrial fibrillation (AF). The pathophysiological relationship between consumption and AF is complex multifactorial. However, there conflicting information about impact (in various doses types) on AF-related outcomes. Alcohol significantly associated with in a gender-independent manner. widespread belief that moderate amounts alcohol, especially red wine, have cardioprotective effects may mean more people will use alcohol. Even small regularly consumed increase AF. In this narrative review, we review epidemiological associations AF, implications incident

Language: Английский

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Roles and mechanisms of natural drugs on sinus node dysfunction

Biomedicine & Pharmacotherapy, Journal Year: 2023, Volume and Issue: 164, P. 114777 - 114777

Published: May 23, 2023

Sinus node dysfunction is a common arrhythmia disorder with high incidence and significant social economic burden. Currently, there are no effective drugs for treating chronic sinus dysfunction. The disease associated ion channel disturbances caused by aging, fibrosis, inflammation, oxidative stress, autonomic Natural active substances Chinese herbal medicines have been widely used extensively studied in the medical community treatment of arrhythmias. Multiple studies demonstrated that various ingredients medicines, such as astragaloside IV, quercetin, ginsenosides, exhibit antioxidant effects, reduce maintain stability, providing promising This article summarizes research progress on natural formulas regulate sick sinoatrial function, valuable references

Language: Английский

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Coffee: Fuel for Your Day or Foe for Your Arteries

Antioxidants, Journal Year: 2024, Volume and Issue: 13(12), P. 1455 - 1455

Published: Nov. 27, 2024

Atherosclerosis, a major cause of cardiovascular diseases, is influenced by modifiable factors such as adiposity and blood cholesterol. Diet crucial in these areas, particularly regarding antioxidant, inflammatory, obesity effects. Coffee, globally popular stimulant beverage, has garnered significant attention for its potential impact on diseases. Recent insights reinforce the need to re-examine relationship between coffee consumption atherosclerosis progression. Coffee’s complex composition includes polyphenols, renowned their antioxidant anti-inflammatory properties well weight-reducing In addition, studies have demonstrated that certain compounds chlorogenic acid, caffeic, p-coumaric, ferulic acid can prevent atherogenesis preventing oxidation low-density lipoproteins. Conversely, diterpenes, found some brews, elevate cholesterol levels, posing risk coronary health. Notably, intake been shown influence gut microbiota diversity, potentially contributing anti-obesity This review explores from preclinical clinical investigating mechanisms through which may reduce atherosclerosis—highlighting benefits moderate filtered risks associated with excessive consumption. Understanding this informing public health recommendations guiding future research.

Language: Английский

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Common Questions and Misconceptions About Energy Drinks: What Does the Scientific Evidence Really Show?

Nutrients, Journal Year: 2024, Volume and Issue: 17(1), P. 67 - 67

Published: Dec. 27, 2024

Energy drinks are a commonly consumed beverage, and studies suggest possible performance-enhancing effect. A Google Scholar search using the keywords “energy drinks” “exercise” yields numerous results, underscoring voluminous research on this topic. However, there questions regarding effectiveness safety of energy drinks. These include, but not limited to: (1) What main active ingredients in drinks? (2) Do assist weight management? (3) enhance aerobic performance? (4) athletic speed? (5) improve reaction time? (6) lean tissue mass? (7) Can cognitive (8) Does acute consumption elevate resting expenditure? (9) Is any evidence to that more effective than an identical serving caffeine alone? (10) Are sex differences response drink consumption? (11) affect sleep or sleepiness? (12) Should pregnant women avoid (13) adversely cardiovascular function? (14) consuming cause brain damage? (15) other considerations (16) (17) If is ingredient coffee, why discrepancy adverse events reported for each? To address these questions, we performed evidence-based scientific evaluation literature supplementation.

Language: Английский

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Night shifts and consumption of energy drinks by healthcare personnel

Beverage Plant Research, Journal Year: 2024, Volume and Issue: 4(1), P. 0 - 0

Published: Jan. 1, 2024

The consumption of drinks with a high caffeine content is growing phenomenon not only among young people but also individuals who work night shifts, including healthcare workers. In people, the motivations that lead to taking energy are linked performance in studies and recreational activities. workers, need maintain level wakefulness during night. This review analyzes published on personnel changes have occurred recent years following stress caused by pandemic healthcare.

Language: Английский

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Instituto de pesquisa café e saúde: Prevenção de doenças e melhora da qualidade de vida

Research Society and Development, Journal Year: 2024, Volume and Issue: 13(5), P. e1513545666 - e1513545666

Published: May 5, 2024

O café é a segunda bebida mais consumida no mundo, depois da água, sendo ‘commodity’ em volumes de negócio. Brasil o maior produtor café, responsável por 1/3 produção mundial e exportador não processado, gerando uma renda cerca 800 milhões dólares anuais, valor aumentaria com aumento do consumo país, sensibilizando consumidor brasileiro dos benefícios refutando cientificamente os seus supostos malefícios. Defender que deve ser considerado um nutracêutico, seria esteio desta sensibilização. Este artigo propõe contribuir, partir evidências científicas, para criação, Brasil, Instituto Pesquisa Café Saúde. Para isso foi realizada revisão bibliográfica. Observamos apesar importância econômica agronegócio existe mundo está idealmente posicionado implementar pioneiro, pois temos inúmeros grupos pesquisa reconhecimento internacional das pesquisas sobre impacto na saúde humana. contribuiria contrariando, generalização errônea “excitante”, potencial dependência danos longo prazo, contribuindo economicamente indústria cafeeira Brasil. Uma Instituição Federal teria abrangência organizacional liderar este capaz ampliar, modo estável sustentado, associada ao café.

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