Differential Functional Connectivity along the Long Axis of the Hippocampus Aligns with Differential Role in Memory Specificity and Generalization DOI Open Access
Lea E. Frank, Caitlin R. Bowman, Dagmar Zeithamová

et al.

Journal of Cognitive Neuroscience, Journal Year: 2019, Volume and Issue: 31(12), P. 1958 - 1975

Published: Aug. 9, 2019

The hippocampus contributes to both remembering specific events and generalization across events. Recent work suggests that information may be represented along the longitudinal axis of at varied levels specificity: detailed representations in posterior generalized anterior hippocampus. Similar distinctions are thought exist within neocortex, with lateral prefrontal parietal regions supporting memory specificity ventromedial temporal cortices memory. Here, we tested whether functional connectivity cortical is consistent these proposed dissociations. We predicted greater putative regions. Furthermore, differences stable under varying task engagement. Participants learned categorize a set stimuli outside scanner, followed by an fMRI session included rest scan, passive viewing runs, category runs. Analyses revealed stronger pFC angular gyrus inferior frontal These remained relatively three phases (rest, viewing, generalization). Whole-brain analyses further widespread hippocampus, little overlap. results contribute our understanding organization long suggest distinct hippocampal–cortical connections one mechanism which represents individual experiences knowledge.

Language: Английский

Hippocampus and temporal pole functional connectivity is associated with age and individual differences in autobiographical memory DOI Creative Commons
Roni Setton, Laetitia Mwilambwe-Tshilobo, Signy Sheldon

et al.

Proceedings of the National Academy of Sciences, Journal Year: 2022, Volume and Issue: 119(41)

Published: Oct. 3, 2022

Recollection of one’s personal past, or autobiographical memory (AM), varies across individuals and the life span. This manifests in amount episodic content recalled during AM, which may reflect differences associated functional brain networks. We take an individual approach to examine resting-state connectivity temporal lobe regions known coordinate AM retrieval with default network (anterior posterior hippocampus, pole) test for associations AM. Multiecho magnetic resonance imaging (fMRI) interviews were collected 158 younger 105 older healthy adults. Interviews scored internal (episodic) external (semantic) details. Age group profiles revealed that adults had lower within anterior pole but greater compared pattern was positively related hippocampal volumes adults, smaller than adult volumes. Connectivity showed two significant patterns. The first dissociated vs. participants. Internal hippocampus orbitofrontal cortex hippocampus. External lateral cortex. In second pattern, displayed throughout more detailed AMs overall. Our findings provide evidence discrete ensembles scale systematic variation recollective styles

Language: Английский

Citations

31
Hippocampal-cortical interactions during event boundaries support retention of complex narrative events DOI
Alexander J. Barnett,

Mitchell Nguyen,

James Spargo

et al.

Neuron, Journal Year: 2023, Volume and Issue: 112(2), P. 319 - 330.e7

Published: Nov. 8, 2023

Language: Английский

Citations

20
The validated circular shape space: Quantifying the visual similarity of shape. DOI
Aedan Y. Li,

Jackson C. Liang,

Andy Lee

et al.

Journal of Experimental Psychology General, Journal Year: 2019, Volume and Issue: 149(5), P. 949 - 966

Published: Oct. 3, 2019

Subjective similarity holds a prominent place in many psychological theories, influencing diverse cognitive processes ranging from attention and categorization to memory problem solving. Despite the known importance of subjective similarity, there are few resources available experimenters interested manipulating visual shape, one common type similarity. Here, across seven validation iterations, we incrementally developed stimulus space consisting 360 shapes using novel image-processing method conjunction with collected judgments. The result is Validated Circular Shape space, first comparable commonly used "color wheel", whereby angular distance along 2D circle proxy for This extensively validated resource freely wishing precisely manipulate shape. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

Language: Английский

Citations

54
Dynamic internal states shape memory retrieval DOI Creative Commons
Hannah Tarder-Stoll, Manasi Jayakumar, Halle R. Dimsdale-Zucker

et al.

Neuropsychologia, Journal Year: 2019, Volume and Issue: 138, P. 107328 - 107328

Published: Dec. 27, 2019

Language: Английский

Citations

51
Differential Functional Connectivity along the Long Axis of the Hippocampus Aligns with Differential Role in Memory Specificity and Generalization DOI Open Access
Lea E. Frank, Caitlin R. Bowman, Dagmar Zeithamová

et al.

Journal of Cognitive Neuroscience, Journal Year: 2019, Volume and Issue: 31(12), P. 1958 - 1975

Published: Aug. 9, 2019

The hippocampus contributes to both remembering specific events and generalization across events. Recent work suggests that information may be represented along the longitudinal axis of at varied levels specificity: detailed representations in posterior generalized anterior hippocampus. Similar distinctions are thought exist within neocortex, with lateral prefrontal parietal regions supporting memory specificity ventromedial temporal cortices memory. Here, we tested whether functional connectivity cortical is consistent these proposed dissociations. We predicted greater putative regions. Furthermore, differences stable under varying task engagement. Participants learned categorize a set stimuli outside scanner, followed by an fMRI session included rest scan, passive viewing runs, category runs. Analyses revealed stronger pFC angular gyrus inferior frontal These remained relatively three phases (rest, viewing, generalization). Whole-brain analyses further widespread hippocampus, little overlap. results contribute our understanding organization long suggest distinct hippocampal–cortical connections one mechanism which represents individual experiences knowledge.

Language: Английский

Citations

47