Abstract
Background
Exercise
training
is
beneficial
in
enhancing
physical
function
and
quality
of
life
cancer
patients.
Its
comprehensive
implementation
remains
challenging,
underlying
cardiopulmonary
adaptations
are
poorly
investigated.
This
randomized
controlled
trial
examines
the
effects
home-based
online
on
variables
activity.
Methods
Of
screened
post-surgical
patients
with
breast,
prostate,
or
colorectal
cancer,
148
were
randomly
assigned
(1:1)
to
an
intervention
(2
×
30
min/week
strength-endurance
using
video
presentations)
a
control
group.
All
received
activity
feedback
during
6-month
period.
Primary
endpoint
was
change
oxygen
uptake
after
6
months.
Secondary
endpoints
included
changes
cardiac
output,
rate
pressure
product,
(EORTC
QoL-C30),
C-reactive
protein,
behavior.
Results
One
hundred
twenty-two
(62
60
group)
completed
study
Change
between
1.8
vs.
0.66
ml/kg/min
(estimated
difference
months:
1.24;
95%
CI
0.23
2.55;
p
=
0.017).
Rate
product
reduced
IG
−
1079;
2157
1;
0.05).
Physical
per
week
not
different
CG.
There
no
significant
interaction
body
composition,
life.
Conclusions
Home-based
among
post-surgery
revealed
increase
decrease
myocardial
workload
exercise.
The
area-wide
as
integral
component
care
studies
investigating
long-term
needed.
Trial
registration
DRKS-ID:
DRKS00020499
;
Registered
17
March
2020.
GeroScience,
Год журнала:
2023,
Номер
45(6), С. 3211 - 3239
Опубликована: Июль 26, 2023
Abstract
Physical
activity,
including
walking,
has
numerous
health
benefits
in
older
adults,
supported
by
a
plethora
of
observational
and
interventional
studies.
Walking
decreases
the
risk
or
severity
various
outcomes
such
as
cardiovascular
cerebrovascular
diseases,
type
2
diabetes
mellitus,
cognitive
impairment
dementia,
while
also
improving
mental
well-being,
sleep,
longevity.
Dose-response
relationships
for
walking
duration
intensity
are
established
adverse
outcomes.
Walking’s
favorable
effects
on
factors
attributed
to
its
impact
circulatory,
cardiopulmonary,
immune
function.
Meeting
current
physical
activity
guidelines
briskly
30
min
per
day
5
days
can
reduce
several
age-associated
diseases.
Additionally,
low-intensity
exercise,
exerts
anti-aging
helps
prevent
age-related
making
it
powerful
tool
promoting
healthy
aging.
This
is
exemplified
lifestyles
individuals
Blue
Zones,
regions
world
with
highest
concentration
centenarians.
other
activities
contribute
significantly
longevity
these
regions,
being
an
integral
part
their
daily
lives.
Thus,
incorporating
into
routines
encouraging
walking-based
interventions
be
effective
strategy
aging
all
populations.
The
goal
this
review
provide
overview
vast
consistent
evidence
supporting
specific
focus
discuss
outcomes,
prevention
Furthermore,
will
delve
molecular
cellular
mechanisms
aging,
providing
insights
underlying
biological
through
which
beneficial
effects.
British Journal of Sports Medicine,
Год журнала:
2024,
Номер
58(10), С. 556 - 566
Опубликована: Апрель 9, 2024
Objective
To
examine
and
summarise
evidence
from
meta-analyses
of
cohort
studies
that
evaluated
the
predictive
associations
between
baseline
cardiorespiratory
fitness
(CRF)
health
outcomes
among
adults.
Design
Overview
systematic
reviews.
Data
source
Five
bibliographic
databases
were
searched
January
2002
to
March
2024.
Results
From
9062
papers
identified,
we
included
26
We
found
eight
described
five
unique
mortality
general
populations.
CRF
had
largest
risk
reduction
for
all-cause
when
comparing
high
versus
low
(HR=0.47;
95%
CI
0.39
0.56).
A
dose–response
relationship
every
1-metabolic
equivalent
task
(MET)
higher
level
was
associated
with
a
11%–17%
in
(HR=0.89;
0.86
0.92,
HR=0.83;
0.78
0.88).
For
incident
outcomes,
nine
12
outcomes.
heart
failure
(HR=0.31;
0.19
0.49).
1-MET
18%
(HR=0.82;
0.79
0.84).
Among
those
living
chronic
conditions,
four
patient
groups.
cardiovascular
disease
(HR=0.27;
0.16
0.48).
The
certainty
across
all
ranged
very
low-to-moderate
according
Grading
Recommendations,
Assessment,
Development
Evaluations.
Conclusion
consistent
is
strongly
lower
variety
conditions
clinical
