Tire-rubber related pollutant 6-PPD quinone: A review of its transformation, environmental distribution, bioavailability, and toxicity

Journal of Hazardous Materials, Год журнала: 2023, Номер 459, С. 132265 - 132265

Опубликована: Авг. 15, 2023

Язык: Английский

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Environmental Occurrence and Toxicity of 6PPD Quinone, an Emerging Tire Rubber-Derived Chemical: A Review

Environmental Science & Technology Letters, Год журнала: 2023, Номер 10(10), С. 815 - 823

Опубликована: Сен. 1, 2023

N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) is a chemical added to tires prevent their oxidative degradation. 6PPD highly reactive with ozone and oxygen, leading the formation of transformation products such as quinone (6PPDQ) on tire surfaces and, subsequently, in road wear particles. 6PPDQ toxicant that has been found roadway runoff receiving water systems. Its presence municipal stormwater led acute mortality coho salmon during migration urban creeks reproduce, generating global interest studying its occurrence toxicity environment. This review aims provide critical overview current state knowledge 6PPDQ, assisting researchers policymakers understanding potential impacts this emerging environment human health. As there are many unanswered questions surrounding further research needed. highlights importance including regulations for 6PPD, well all synthetic chemicals concern.

Язык: Английский

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Four-week repeated exposure to tire-derived 6-PPD quinone causes multiple organ injury in male BALB/c mice

The Science of The Total Environment, Год журнала: 2023, Номер 894, С. 164842 - 164842

Опубликована: Июнь 17, 2023

Язык: Английский

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Where the rubber meets the road: Emerging environmental impacts of tire wear particles and their chemical cocktails

The Science of The Total Environment, Год журнала: 2024, Номер 927, С. 171153 - 171153

Опубликована: Март 7, 2024

About 3 billion new tires are produced each year and about 800 million become waste annually. Global dependence upon from natural rubber petroleum-based compounds represents a persistent complex environmental problem with only partial often-times, ineffective solutions. Tire emissions may be in the form of whole tires, tire particles, chemical compounds, which is transported through various atmospheric, terrestrial, aquatic routes built environments. Production use generates multiple heavy metals, plastics, PAH's, other that can toxic alone or as cocktails. Used require storage space, energy intensive to recycle, generally have few post-wear uses not also potential sources pollutants (e.g., crumb rubber, pavements, burning). particles emitted during major component microplastics urban runoff source unique highly potent substances. Thus, represent ubiquitous pollutant requires comprehensive examination develop effective management remediation. We approach issue pollution holistically by examining life cycle across production, emissions, recycling, disposal. In this paper, we synthesize recent research data human health risks associated use, disposal discuss gaps our knowledge fate transport, well toxicology leachates. examine remediation approaches for addressing exposure tires. consider three levels: their state, particulates, mixture Finally, information understanding outline key questions improve ability manage remediate pollution.

Язык: Английский

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Widespread occurrence of two typical N, N’-substituted p-phenylenediamines and their quinones in humans: Association with oxidative stress and liver damage

Journal of Hazardous Materials, Год журнала: 2024, Номер 468, С. 133835 - 133835

Опубликована: Фев. 19, 2024

Язык: Английский

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Occurrence of p-phenylenediamine antioxidants in human urine

The Science of The Total Environment, Год журнала: 2024, Номер 914, С. 170045 - 170045

Опубликована: Янв. 12, 2024

Язык: Английский

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Polyethylene nanoparticles at environmentally relevant concentrations enhances neurotoxicity and accumulation of 6-PPD quinone in Caenorhabditis elegans

The Science of The Total Environment, Год журнала: 2024, Номер 918, С. 170760 - 170760

Опубликована: Фев. 6, 2024

Язык: Английский

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Evaluation of 6-PPD quinone toxicity on lung of male BALB/c mice by quantitative proteomics

The Science of The Total Environment, Год журнала: 2024, Номер 922, С. 171220 - 171220

Опубликована: Фев. 25, 2024

Язык: Английский

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Comparison of intestinal toxicity in enhancing intestinal permeability and in causing ROS production of six PPD quinones in Caenorhabditis elegans

The Science of The Total Environment, Год журнала: 2024, Номер 927, С. 172306 - 172306

Опубликована: Апрель 7, 2024

Язык: Английский

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Exposure to 6-PPD quinone causes ferroptosis activation associated with induction of reproductive toxicity in Caenorhabditis elegans

Journal of Hazardous Materials, Год журнала: 2024, Номер 471, С. 134356 - 134356

Опубликована: Апрель 19, 2024

Язык: Английский

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