Carbon, Journal Year: 2020, Volume and Issue: 161, P. 784 - 793
Published: Feb. 4, 2020
Language: Английский
Chemical Society Reviews, Journal Year: 2018, Volume and Issue: 48(6), P. 1642 - 1667
Published: Nov. 26, 2018
Hydrogels have emerged as a promising bioelectronic interfacing material. This review discusses the fundamentals and recent advances in hydrogel bioelectronics.
Language: Английский
Citations
1642
ACS Nano, Journal Year: 2021, Volume and Issue: 15(12), P. 18895 - 18930
Published: Dec. 6, 2021
Light is an attractive tool that has a profound impact on modern medicine. Particularly, light-based photothermal therapy (PTT) and photodynamic (PDT) show great application prospects in the prevention of wound infection promoting healing. In addition, hydrogels have shown advantages field dressings due to their excellent biochemical effects. Therefore, multifunctional photoresponsive (MPRHs) integrate light are increasingly used biomedicine, especially repair. However, comprehensive review MPRHs for regeneration still lacking. This first focuses various types prepared by diverse photosensitizers, agents (PHTAs) including transition metal sulfide/oxides nanomaterials, nanostructure-based PHTAs, carbon-based conjugated polymer or complex-based and/or (PHDAs) such as ZnO-based, black-phosphorus-based, TiO2-based, small organic molecule-based PHDAs. We also then discuss how PTT, PDT, photothermal/photodynamic synergistic can modulate microenvironments bacteria inhibit infection. Overall, with both therapeutic tissue capabilities been discussed existing challenges, well future research directions management argued.
Language: Английский
Citations
424
Bioactive Materials, Journal Year: 2021, Volume and Issue: 8, P. 267 - 295
Published: July 6, 2021
Polymeric hydrogels are fascinating platforms as 3D scaffolds for tissue repair and delivery systems of therapeutic molecules cells. Among others, methacrylated gelatin (GelMA) has become a representative hydrogel formulation, finding various biomedical applications. Recent efforts on GelMA-based have been devoted to combining them with bioactive functional nanomaterials, aiming provide enhanced physicochemical biological properties GelMA. The benefits this approach multiple: i) reinforcing mechanical properties, ii) modulating viscoelastic property allow printability bio-inks, iii) rendering electrical/magnetic produce electro-/magneto-active the specific tissues (e.g., muscle, nerve), iv) providing stimuli-responsiveness actively deliver molecules, v) endowing capacity in process antioxidant effects). nanomaterial-combined GelMA shown significantly extraordinary behaviors (bone, skin, cardiac, nerve) that rarely observable Here we systematically review these recent nanomaterials-combined considered next-generation multifunctional therapeutics. approaches used can also apply other existing polymeric systems.
Language: Английский
Citations
317
Materials, Journal Year: 2019, Volume and Issue: 12(4), P. 624 - 624
Published: Feb. 20, 2019
The unique combination of mechanical, optical and electrical properties offered by carbon nanotubes has fostered research for their use in many kinds applications, including the biomedical field. However, due to persisting outstanding questions regarding potential toxicity when considered as free particles, is now focusing on immobilization substrates interface tuning or biosensors, load nanocomposite materials where they improve both mechanical even direct scaffolds tissue engineering. After a brief introduction general proposed applications field, this review will focus with hydrogel-based matrices especially future diagnostics, engineering targeted drug delivery. issue also be briefly described order justify safe(r)-by-design approach nanotubes-based hydrogels.
Language: Английский
Citations
304
Nanomaterials, Journal Year: 2021, Volume and Issue: 11(4), P. 967 - 967
Published: April 9, 2021
Recent advances in nanomaterial design and synthesis has resulted robust sensing systems that display superior analytical performance. The use of nanomaterials within sensors accelerated new routes opportunities for the detection analytes or target molecules. Among others, carbon-based have reported biocompatibility, better sensitivity, selectivity lower limits to reveal a wide range organic inorganic Carbon are among most extensively studied materials because their unique properties spanning from high specific surface area, carrier mobility, electrical conductivity, flexibility, optical transparency fostering applications. In this paper, comprehensive review been made cover recent developments field describes like fullerenes, carbon onions, quantum dots, nanodiamonds, nanotubes, graphene. Synthesis these nanostructures discussed along with functionalization methods. application all applications highlighted principal applicative future prospects possibilities outlined.
Language: Английский
Citations
258
Colloids and Surfaces B Biointerfaces, Journal Year: 2019, Volume and Issue: 180, P. 411 - 428
Published: May 8, 2019
Language: Английский
Citations
192
Materials Science and Engineering C, Journal Year: 2021, Volume and Issue: 122, P. 111927 - 111927
Published: Feb. 5, 2021
Language: Английский
Citations
162
Nano-Micro Letters, Journal Year: 2020, Volume and Issue: 12(1)
Published: Aug. 18, 2020
Abstract Conductive polymers (CPs) are generally insoluble, and developing hydrophilic CPs is significant to broaden the applications of CPs. In this work, a mussel-inspired strategy was proposed construct CP nanoparticles (CP NPs), while endowing NPs with redox activity biocompatibility. This universal applicable for series CPs, including polyaniline, polypyrrole, poly(3,4-ethylenedioxythiophene). The catechol/quinone contained sulfonated lignin (LS) doped into various form CP/LS hydrophilicity, conductivity, activity. These were used as versatile nanofillers prepare conductive hydrogels long-term adhesiveness. NPs-incorporated have good conductivity because uniform distribution in hydrogel network, forming well-connected electric path. exhibits adhesiveness, which attributed dynamic balance groups on NPs. adhesive shows electroactivity biocompatibility therefore has broad electrostimulation tissue regeneration implantable bioelectronics.
Language: Английский
Citations
156
Nano Research, Journal Year: 2023, Volume and Issue: 16(2), P. 3475 - 3515
Published: Jan. 3, 2023
Language: Английский
Citations
153
Journal of Nanobiotechnology, Journal Year: 2021, Volume and Issue: 19(1)
Published: Dec. 16, 2021
Abstract Despite the exciting breakthroughs in medical technology, cancer still accounts for one of principle triggers death and conventional therapeutic modalities often fail to attain an effective cure. Recently, nanobiotechnology has made huge advancement therapy with gigantic application potential because their ability achieving precise controlled drug release, elevating solubility reducing adverse effects. Carbon nanotubes (CNTs), most promising carbon-related nanomaterials, have already achieved much success biomedical field. Due excellent optical property, thermal electronic conductivity, easy functionalization high loading capacity, CNTs can be applied a multifunctional way treatment diagnosis. In this review, we will give overview recent progress CNT-based delivery systems theranostics, which emphasizes targetability intracellular components tumor cells extracellular elements microenvironment. Moreover, detailed introduction on how penetrate inside reach sites action achieve effects, as well diagnostic applications highlighted. Graphic
Language: Английский
Citations
119