Chitosan-based mussel-inspired hydrogel for rapid self-healing and high adhesion of tissue adhesion and wound dressings

Carbohydrate Polymers, Journal Year: 2023, Volume and Issue: 316, P. 121083 - 121083

Published: June 3, 2023

Language: Английский

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Antimicrobial Hydrogels: Potential Materials for Medical Application

Small, Journal Year: 2023, Volume and Issue: 20(5)

Published: Sept. 26, 2023

Abstract Microbial infections based on drug‐resistant pathogenic organisms following surgery or trauma and uncontrolled bleeding are the main causes of increased mortality from worldwide. The prevalence pathogens has led to a significant increase in medical costs poses great threat normal life people. This is an important issue field biomedicine, emergence new antimicrobial materials hydrogels holds promise for solving this problem. Hydrogel material with good biocompatibility, water absorption, oxygen permeability, adhesion, degradation, self‐healing, corrosion resistance, controlled release drugs as well structural diversity. Bacteria‐disturbing have applications direction surgical treatment, wound dressing, device coating, tissue engineering. paper reviews classification hydrogels, current status research, potential one application analyzes research biomedical five aspects: metal‐loaded drug‐loaded carbon‐material‐loaded fixed activity biological provides outlook high activity, biodegradability, injectability, clinical applicability future development prospects field.

Language: Английский

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Mxene-based wearable self-powered and photothermal triboelectric nanogenerator patches for wound healing acceleration and tactile sensing

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 482, P. 148949 - 148949

Published: Jan. 21, 2024

Language: Английский

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Engineering multifunctional dynamic hydrogel for biomedical and tissue regenerative applications

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 487, P. 150403 - 150403

Published: March 16, 2024

Hydrogels have emerged in various biomedical applications, including tissue engineering and medical devices, due to their ability imitate the natural extracellular matrix (ECM) of tissues. However, conventional static hydrogels lack dynamically respond changes surroundings withstand robust biophysical microenvironment trigger on-demand functionality such as drug release mechanical change. In contrast, multifunctional dynamic can adapt external stimuli drawn great attention recent studies. It is realized that integration nanomaterials into provides numerous functionalities for a variety applications cannot be achieved by hydrogels. This review article comprehensive overview advances designing fabricating applications. We describe different types based on breakable reversible covalent bonds well noncovalent interactions. These mechanisms are described detail useful reference crosslinking strategies strongly influence properties also discuss use potential benefits. further explores nanocomposite hydrogels, delivery, engineering, bioadhesives, wound healing, cancer treatment, mechanistic study, multiple-scale Finally, we challenges future perspectives field diverse technologies.

Language: Английский

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Multifunctional naturally derived bioadhesives: From strategic molecular design toward advanced biomedical applications

Progress in Polymer Science, Journal Year: 2024, Volume and Issue: 150, P. 101792 - 101792

Published: Jan. 26, 2024

In the last decades, adhesives derived from natural resources (i.e., bioadhesives) have emerged as promising alternative to standard wound closure devices, including sutures, clips, and strips, owing relatively easy rapid application, minimal tissue damage, fast hemostasis, ability decrease risk of infection. Various synthetic materials been utilized bioadhesives. These find extensive application in various biomedical fields, ranging simple sealing controlled drug delivery, regeneration, noninvasive therapy. Considering weak underwater adhesion, degradability, biological performances adhesives, naturally derived-based are more attractive. The first generation these bioadhesives provided primarily only one function. Moreover, they had issues long curing time, slow high degradation rate, low mechanical properties, transferring contamination wound. chemically genetically engineered strategies applied advance their multifunctionality. synergy bonding chemistry, topography, mechanics dissipation structure supports improved adhesion rate. developed that cover subjects innovative biomaterial synthesis or functionalization cutting-edge manufacturing processes. However, fulfill all criteria an ideal bioadhesive for clinical applications, efforts should be devoted investigating surface characteristics target tissues long-term relationship between physiochemical properties polymers cohesion mechanisms, well adhesive functionality. This review outlines recent progress on naturally-derived bioadhesives, proteins polysaccharides, focusing designing approaches based engineering strategies, development, applications. Furthermore, challenges current studies summarized show future perspectives developing bioengineered high-performance use.

Language: Английский

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Recent advances of hydrogels as smart dressings for diabetic wounds

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(5), P. 1126 - 1148

Published: Jan. 1, 2024

This review highlights the latest progress of smart hydrogel dressings for bandaging, monitoring and therapy diabetic wounds.

Language: Английский

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Recent advances in smart hydrogels derived from polysaccharides and their applications for wound dressing and healing

Biomaterials, Journal Year: 2025, Volume and Issue: unknown, P. 123134 - 123134

Published: Jan. 1, 2025

Language: Английский

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Bioadhesives with Antimicrobial Properties

Advanced Materials, Journal Year: 2023, Volume and Issue: 35(49)

Published: June 3, 2023

Bioadhesives with antimicrobial properties enable easier and safer treatment of wounds as compared to the traditional methods such suturing stapling. Composed natural or synthetic polymers, these bioadhesives seal facilitate healing while preventing infections through activity locally released drugs, nanocomponents, inherently polers. Although many different materials strategies are employed develop bioadhesives, design biomaterials necessitates a prudent approach achieving all required including optimal adhesive cohesive properties, biocompatibility, can be challenging. Designing tunable physical, chemical, biological will shed light on path for future advancement properties. In this review, requirements commonly used developing discussed. particular, their synthesis experimental clinical applications variety organs reviewed. Advances in pave way better management increase positive outcomes.

Language: Английский

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Incorporating copper-based nanosheets into an injectable self-healing hydrogel enables superb repair of infected diabetic wound

Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 476, P. 146788 - 146788

Published: Oct. 20, 2023

Language: Английский

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Gelatin-based dynamic response antioxidant, anti-inflammatory multifunctional hydrogel for enhanced diabetic wound repair

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 260, P. 129453 - 129453

Published: Jan. 21, 2024

Language: Английский

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