Polymers for Advanced Technologies,
Journal Year:
2024,
Volume and Issue:
35(9)
Published: Sept. 1, 2024
Abstract
Polypropylene
carbonate
(PPC)
is
a
promising
candidate
of
substrate
materials
used
for
human
wearable
devices
due
to
its
excellent
ductility
and
biocompatibility.
However,
PPC
prone
be
deformed,
thus
resulting
in
poor
shape
recovery
property.
One
effective
solution
construct
composites.
In
this
work,
poly
(tannic
acid)
with
Fe
3+
(FPTA)
@
graphene
oxide
(GO)
was
added
fabricate
FPTA@GO/PPC
The
results
show
that
FPTA@GO
can
tight
network
hydrogen
bonds
into
improve
memory
self‐healing
properties.
By
varying
the
content,
composites
exhibit
tunable
Dynamic
mechanical
analysis
confirms
better
properties
compared
pure
PPC.
5
wt%
composite
demonstrates
superior
fixation
ratio
(
R
f
=
99%)
as
well
r
94%)
37°C.
Moreover,
possesses
great
efficiency
81%
tensile
strength
(17.2
MPa).
UV
absorption
capacity
increased
by
150%
(far
mid‐UV
regions)
400%
(near‐UV
region)
Thus,
have
potential
applications
developing
memory,
self‐healing,
UV‐resistant
devices.
Materials Today Bio,
Journal Year:
2025,
Volume and Issue:
30, P. 101436 - 101436
Published: Jan. 5, 2025
Well-designed
artificial
scaffolds
are
urgently
needed
due
to
the
limited
self-repair
capacity
of
bone,
which
hampers
effective
regeneration
in
critical
defects.
Optimal
must
provide
physical
guidance
recruit
cells
and
immune
regulation
improve
regenerative
microenvironment.
This
study
presents
a
novel
scaffold
composed
dual-sided
centripetal
microgrooved
poly(D,L-lactide-co-caprolactone)
(PLCL)
film
combined
with
dynamic
hydrogel
containing
prednisolone
(PLS)-loaded
Prussian
blue
nanoparticles
(PB@PLS).
The
microgrooves
on
surface
PLCL
were
imprinted
using
micropatterned
polydimethylsiloxane
(PDMS)
template.
Following
aminolysis,
was
covalently
grafted
EM-7
peptide
via
glutaraldehyde.
Functional
group
analysis,
morphology
hydrophilicity
evaluated
X-ray
photoelectron
spectroscopy
(XPS),
scanning
electron
microscopy
(SEM),
an
optical
contact
angle
measuring
instrument,
respectively.
Bone
regeneration-related
(e.g.,
bone
marrow
mesenchymal
stem
cells,
macrophages,
Schwann
endothelial
cells)
cultured
films
tended
align
along
stripes
migrate
from
periphery
toward
center
region
vitro.
Subsequently,
encapsulated
immune-regulating
synthesized
thiol-modified
gelatin
Cu2+
presence
PB@PLS
nanoparticles,
demonstrated
excellent
antioxidant
properties.
significantly
accelerated
critical-sized
regeneration,
as
evidenced
by
increase
volume
newly
formed
histological
images
vivo.
innovative
approach
holds
substantial
promise
for
clinical
applications
broader
tissue
repair.
Small Methods,
Journal Year:
2024,
Volume and Issue:
unknown
Published: July 23, 2024
Abstract
Hyaluronic
acid
(HA)
is
a
naturally
occurring
polysaccharide
found
in
the
extracellular
matrix
with
broad
applications
disease
treatment.
HA
possesses
good
biocompatibility,
biodegradability,
and
ability
to
interact
various
cell
surface
receptors.
Its
wide
range
of
molecular
weights
modifiable
chemical
groups
make
it
an
effective
drug
carrier
for
delivery.
Additionally,
overexpression
specific
receptors
on
surfaces
many
states
enhances
accumulation
drugs
at
pathological
sites
through
receptor
binding.
In
this
review,
modification
drugs,
major
proteins,
latest
advances
receptor‐targeted
nano
delivery
systems
(DDS)
treatment
tumors
inflammatory
diseases
are
summarized.
Furthermore,
functions
varying
vivo
selection
methods
different
discussed.
ACS Applied Materials & Interfaces,
Journal Year:
2024,
Volume and Issue:
16(26), P. 32887 - 32905
Published: June 21, 2024
Hydrogel
bioelectronics
has
been
widely
used
in
wearable
sensors,
electronic
skin,
human-machine
interfaces,
and
implantable
tissue-electrode
providing
great
convenience
for
human
health,
safety,
education.
The
generation
of
waste
from
bioelectronic
devices
jeopardizes
health
the
natural
environment.
development
degradable
recyclable
hydrogels
is
recognized
as
a
paradigm
realizing
next
environmentally
friendly
sustainable
bioelectronics.
This
review
first
summarizes
wide
range
applications
bioelectronics,
including
devices.
Then,
employment
synthetic
polymers
hydrogel
discussed
terms
degradability
recyclability.
Finally,
this
work
provides
constructive
thoughts
perspectives
on
current
challenges
toward
valuable
insights
guidance
future
evolution
Biomacromolecules,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 24, 2025
High
levels
of
reactive
oxygen
species
(ROS)
and
hypoxia
in
diabetic
wounds
significantly
hinder
the
healing
process.
In
this
work,
a
kind
catalase-like
nanozyme-hybrid
hydrogel
was
developed
to
explore
potential
harnessing
endogenous
excessive
ROS
as
an
source
synergistically
regulate
oxidative
stress
hypoxia,
thereby
enhancing
wound
healing.
The
hydrogels
exhibited
rapid
degradation
controlled
release
ferrihydrite
nanozymes
response
stress,
which
continuously
catalyzed
decomposition
H2O2
generate
oxygen,
effectively
scavenging
reducing
risk
local
toxicity.
relieved
intracellular
hypoxic
microenvironment
simultaneously
vitro.
dressings
inhibited
damage
at
sites,
promoted
epidermis
formation
collagen
deposition,
accelerated
db/db
mice.
Therefore,
represent
promising
strategy
for
dressings,
addressing
both
improve
outcomes.
