Photocatalytic Antimicrobials: Principles, Design Strategies, and Applications DOI

Bei Ran,

Lei Ran, Zuokai Wang

et al.

Chemical Reviews, Journal Year: 2023, Volume and Issue: 123(22), P. 12371 - 12430

Published: Aug. 24, 2023

Nowadays, the increasing emergence of antibiotic-resistant pathogenic microorganisms requires search for alternative methods that do not cause drug resistance. Phototherapy strategies (PTs) based on photoresponsive materials have become a new trend in inactivation due to their spatiotemporal controllability and negligible side effects. Among those phototherapy strategies, photocatalytic antimicrobial therapy (PCAT) has emerged as an effective promising strategy recent years. In process treatment, are excited by different wavelengths lights produce reactive oxygen species (ROS) or other toxic killing various microbes, such bacteria, viruses, fungi, parasites, algae. Therefore, this review timely summarizes latest progress PCAT field, with emphasis development antimicrobials (PCAMs), underlying mechanisms, design multiple practical applications local infections therapy, personal protective equipment, water purification, coatings, wound dressings, food safety, antibacterial textiles, air purification. Meanwhile, we also present challenges perspectives widespread implementation therapeutics. We hope result review, will flourish weapon against antibiotic

Language: Английский

Green Tea Derivative Driven Smart Hydrogels with Desired Functions for Chronic Diabetic Wound Treatment DOI
Xiaodan Zhao, Dandan Pei, Yuxuan Yang

et al.

Advanced Functional Materials, Journal Year: 2021, Volume and Issue: 31(18)

Published: Feb. 1, 2021

Abstract Current treatments for chronic diabetic wounds remain unsatisfactory due to the lack of ideal wound dressings that can integrate matching mechanical strength, fast self‐healability, facile dressing change, and multiple therapeutic effects into one system. In this work, benefiting from catechol groups effect epigallocatechin‐3‐gallate (EGCG, green tea derivative), a smart hydrogel be conveniently obtained through copolymerization complex formed by EGCG 3‐acrylamido phenylboronic acid (APBA) (the formation boronate ester bond) acrylamide. The resulting features adequate properties, self‐healing capability, tissue adhesiveness. Otherwise, substantial release not only realize anti‐oxidation, antibacterial, anti‐inflammatory proangiogenic effect, modulation macrophage polarization accelerate healing, but also facilitate easy change. This advanced provides effective way management may extended therapy other complicated healings.

Language: Английский

Citations

404

Polydopamine antibacterial materials DOI
Yu Fu, Lei Yang, Jianhua Zhang

et al.

Materials Horizons, Journal Year: 2021, Volume and Issue: 8(6), P. 1618 - 1633

Published: Jan. 1, 2021

This review focuses on the recent progress in polydopamine antibacterial materials, including their structural and functional features, preparation strategies, mechanisms, biomedical applications.

Language: Английский

Citations

384

Biomaterial-based antimicrobial therapies for the treatment of bacterial infections DOI
Pranav P. Kalelkar, Milan Riddick, Andrés J. Garcı́a

et al.

Nature Reviews Materials, Journal Year: 2021, Volume and Issue: 7(1), P. 39 - 54

Published: Sept. 15, 2021

Language: Английский

Citations

364

Wound Dressing: From Nanomaterials to Diagnostic Dressings and Healing Evaluations DOI
Qiankun Zeng, Xiaoliang Qi, Guoyue Shi

et al.

ACS Nano, Journal Year: 2022, Volume and Issue: 16(2), P. 1708 - 1733

Published: Jan. 20, 2022

Wound dressings based on nanomaterials play a crucial role in wound treatment and are widely used whole range of medical settings, from minor to life-threatening tissue injuries. This article presents an educational review the accumulating knowledge this multidisciplinary area lay out challenges opportunities that lie ahead ignite further faster development clinically valuable technologies. The analyzes functional advantages nanomaterial-based gauzes hydrogels as well hybrid structures thereof. On basis, state-of-the-art advances transfer (semi)blind approaches evaluation state smart enable real-time monitoring diagnostic functions could help during healing. explores translation related aspects into real-world use. ongoing future associated with clinical decisions presented reviewed.

Language: Английский

Citations

336

Antibacterial biomaterials for skin wound dressing DOI Creative Commons

Yuqing Liang,

Yongping Liang, Hualei Zhang

et al.

Asian Journal of Pharmaceutical Sciences, Journal Year: 2022, Volume and Issue: 17(3), P. 353 - 384

Published: Jan. 24, 2022

Bacterial infection and the ever-increasing bacterial resistance have imposed severe threat to human health. And contamination could significantly menace wound healing process. Considering sophisticated process, novel strategies for skin tissue engineering are focused on integration of bioactive ingredients, antibacterial agents included, into biomaterials with different morphologies improve cell behaviors promote healing. However, a comprehensive review anti-bacterial dressing enhance has not been reported. In this review, various as dressings will be discussed. Different kinds agents, including antibiotics, nanoparticles (metal metallic oxides, light-induced agents), cationic organic others, their recent advances summarized. Biomaterial selection fabrication structures forms, films, hydrogel, electrospun nanofibers, sponge, foam three-dimension (3D) printed scaffold regeneration, elaborated Current challenges future perspectives presented in multidisciplinary field. We envision that provide general insight elegant design further refinement dressing.

Language: Английский

Citations

332

Injectable Self-Healing Adhesive Chitosan Hydrogel with Antioxidative, Antibacterial, and Hemostatic Activities for Rapid Hemostasis and Skin Wound Healing DOI

Shen Guo,

Yikun Ren,

Rong Chang

et al.

ACS Applied Materials & Interfaces, Journal Year: 2022, Volume and Issue: 14(30), P. 34455 - 34469

Published: July 20, 2022

Engineered wound dressing materials with excellent injectability, self-healing ability, tissue-adhesiveness, especially the ones possessing potential therapeutic effects have great practical significance in healthcare. Herein, an injectable quaternary ammonium chitosan (QCS)/tannic acid (TA) hydrogel based on QCS and TA was designed fabricated by facile mixing of two ingredients under physiological conditions. In this system, hydrogels were mainly cross-linked dynamic ionic bonds hydrogen between TA, which endows injectable, self-healing, adhesive properties. Benefitting from inherent antioxidative, antibacterial, hemostatic abilities QCS, showed superior reactive oxygen species scavenging activity, broad-spectrum antibacterial as well rapid capability. Moreover, QCS/TA2.5 (containing 2.5% TA) exhibited biocompatibility. The vivo experiments also that not only rapidly stopped bleeding arterial deep incompressible wounds mouse tail amputation, femoral artery hemorrhage, liver incision models but significantly accelerated healing a full-thickness skin model. For potentials listed above, multifunctional offers promising network material for both hemostasis repair.

Language: Английский

Citations

284

Defect‐Rich Adhesive Molybdenum Disulfide/rGO Vertical Heterostructures with Enhanced Nanozyme Activity for Smart Bacterial Killing Application DOI
Longwei Wang,

Fene Gao,

Aizhu Wang

et al.

Advanced Materials, Journal Year: 2020, Volume and Issue: 32(48)

Published: Oct. 28, 2020

Abstract Nanomaterials with intrinsic enzyme‐like activities, namely “nanozymes,” are showing increasing potential as a new type of broad‐spectrum antibiotics. However, their feasibility is still far from satisfactory, due to low catalytic activity, poor bacterial capturing capacity, and complicated material design. Herein, facile synthesis defect‐rich adhesive molybdenum disulfide (MoS 2 )/rGO vertical heterostructure (VHS) through one‐step microwave‐assisted hydrothermal method reported. This simple, convenient but effective for rapid enables extremely uniform well‐dispersed MoS /rGO VHS abundant S Mo vacancies rough surface, performance approaching the requirements practical application. It demonstrated experimentally theoretically that as‐prepared possesses defect irradiation dual‐enhanced triple activities (oxidase, peroxidase, catalase) promoting free‐radical generation, owing much more active edge sites exposure. Meanwhile, VHS‐achieved surface exhibits excellent capacity capture, elevated reactive oxygen species (ROS) destruction local topological interactions. As result, optimized efficacy against drug‐resistant Gram‐negative Gram‐positive bacteria can be explored by such nanozymes, demonstrating simple powerful way engineered nanozymes alternative

Language: Английский

Citations

265

An overview of the use of nanozymes in antibacterial applications DOI
Linqiang Mei, Shuang Zhu, Yaping Liu

et al.

Chemical Engineering Journal, Journal Year: 2021, Volume and Issue: 418, P. 129431 - 129431

Published: March 21, 2021

Language: Английский

Citations

257

Synergistic antibacterial strategy based on photodynamic therapy: Progress and perspectives DOI
Xianjin Hu, Heng Zhang, Yanting Wang

et al.

Chemical Engineering Journal, Journal Year: 2022, Volume and Issue: 450, P. 138129 - 138129

Published: July 16, 2022

Language: Английский

Citations

248

Design, optimization, and nanotechnology of antimicrobial peptides: From exploration to applications DOI
Peng Tan,

Huiyang Fu,

Xi Ma

et al.

Nano Today, Journal Year: 2021, Volume and Issue: 39, P. 101229 - 101229

Published: July 5, 2021

Language: Английский

Citations

242