4D printing of shape memory polymer composites: A review on fabrication techniques, applications, and future perspectives

Journal of Manufacturing Processes, Journal Year: 2022, Volume and Issue: 81, P. 759 - 797

Published: July 25, 2022

Language: Английский

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4D bioprinting of smart polymers for biomedical applications: recent progress, challenges, and future perspectives

Reactive and Functional Polymers, Journal Year: 2022, Volume and Issue: 179, P. 105374 - 105374

Published: Aug. 10, 2022

4D bioprinting is the next-generation additive manufacturing-based fabrication platform employed to construct intricate, adaptive, and dynamic soft hard tissue structures as well biomedical devices. It achieved by using stimuli-responsive materials, especially shape memory polymers (SMPs) hydrogels, which possess desirable biomechanical characteristics. In last few years, numerous efforts have been made printing community develop novel polymeric materials considering their perspective. This review presents an up-to-date overview of technology incorporating functionalities biomaterials focused approach towards different engineering regenerative medicine (TERM) applications. includes bone, cardiac, neural, cartilage, drug delivery systems, other high-value also addresses current limitations challenges in provide a basis for foreseeable advancements TERM applications that could be helpful successful utilization clinical settings.

Language: Английский

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A review on four-dimensional (4D) bioprinting in pursuit of advanced tissue engineering applications

Bioprinting, Journal Year: 2022, Volume and Issue: 27, P. e00203 - e00203

Published: March 30, 2022

Language: Английский

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Recent Advances in the Additive Manufacturing of Stimuli‐Responsive Soft Polymers

Advanced Engineering Materials, Journal Year: 2023, Volume and Issue: 25(21)

Published: Aug. 29, 2023

Stimuli‐responsive polymers (SRPs) are special types of soft materials, which have been extensively used for developing flexible actuators, robots, wearable devices, sensors, self‐expanding structures, and biomedical thanks to their ability change shapes functional properties in response external stimuli including light, humidity, heat, pH, electric field, solvent, magnetic field or combinations two more these stimuli. In recent years, additive manufacturing (AM) aka 3D printing technology SRPs, also known as 4D printing, has gained phenomenal attention different engineering fields, its unique develop complex, personalized, innovative undergo twisting, elongating, swelling, rolling, shrinking, bending, spiraling, other complex morphological transformations. Herein, an effort made provide insightful information about the AM techniques, type applications including, but not limited tissue engineering, bionics, construction, smart textiles. This article incorporates current challenges prospects, hoping basis utilization this fields. It is expected that amalgamation with SRPs would unparalleled advantages arenas.

Language: Английский

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Research Progress of Shape Memory Polymer and 4D Printing in Biomedical Application

Advanced Healthcare Materials, Journal Year: 2022, Volume and Issue: 12(16)

Published: Dec. 15, 2022

Abstract As a kind of smart material, shape memory polymer (SMP) shows great application potential in the biomedical field. Compared with traditional metal‐based medical devices, SMP‐based devices have following characteristics: 1) The adaptive ability allows device to better match surrounding tissue after being implanted into body by minimally invasive implantation; 2) it has biocompatibility and adjustable biodegradability; 3) mechanical properties can be regulated large range tissue. 4D printing technology is comprehensive based on materials 3D printing, which value breaks through technical bottleneck personalized customization provides new opportunity for further development This paper summarizes SMP field bone scaffolds, tracheal drug release, etc. Moreover, this analyzes existing problems prospects, hoping provide preliminary discussion useful reference engineering.

Language: Английский

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3D printing of magneto-active smart materials for advanced actuators and soft robotics applications

European Polymer Journal, Journal Year: 2024, Volume and Issue: 205, P. 112718 - 112718

Published: Jan. 2, 2024

In the contemporary era, novel manufacturing technologies like additive (AM) have revolutionized different engineering sectors including biomedical, aerospace, electronics, etc. Four-dimensional (4D) printing aka AM of smart materials is gaining popularity among scientific community, which has excellent ability to make soft structures such as robots, actuators, and grippers. These are developed by applying various stimuli pH, temperature, magnetic field, many combinations onto materials. Stimuli in 3D permit shape-morphing behaviors bending, twisting, folding, swelling, rolling, shrinking, origami, or locomotion. A wide variety can be fabricated through incorporation hard particles into resulting magneto-active (MASMs). With this integration, magneto-thermal coupling actuation allows diverse magneto-deformations, facilitating development personalized devices that capable enhanced deformation. review, guidelines provided on for MASMs polymers (MAPs), composites, hydrogels (MAHs) booming flexible wearable biomimetic devices. Moreover, 3D-printed robotics an outstanding capacity adapt complicated situations advanced actuating applications. Finally, some current challenges emerging areas exciting technology been proposed. Lastly, it anticipated technological advancements developing intelligent will a significant impact design real-world

Language: Английский

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3D printing of stimuli-responsive hydrogel materials: Literature review and emerging applications

Giant, Journal Year: 2023, Volume and Issue: 17, P. 100209 - 100209

Published: Nov. 15, 2023

Additive manufacturing (AM) aka three-dimensional (3D) printing has been a well-established and unparalleled technology, which is expanding the boundaries of materials science exhibiting an enormous potential to fabricate intricate geometries for healthcare, electronics, construction sectors. In contemporary era, combination AM technology stimuli-responsive hydrogels (SRHs) helps create dynamic functional structures with extreme accuracy, are capable changing their shape, functional, or mechanical properties in response environmental cues such as humidity, heat, light, pH, magnetic field, electric etc. 3D SRHs permits creation on-demand dynamically controllable shapes excellent control over various self-repair, self-assembly, multi-functionality, These accelerate researchers think unthinkable applications. Additively manufactured objects have shown applications like tissue engineering, drug delivery, soft robots, sensors, other biomedical devices. The current review provides recent progress SRHs, more focus on techniques, stimuli mechanisms, shape morphing behaviors, Finally, trends future roadmap additively smart different also presented, will be helpful research. This holds great promise providing fundamental knowledge about diverse

Language: Английский

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Multimaterial 3D and 4D Bioprinting of Heterogenous Constructs for Tissue Engineering

Advanced Materials, Journal Year: 2023, Volume and Issue: 36(34)

Published: Sept. 22, 2023

Additive manufacturing (AM), which is based on the principle of layer-by-layer shaping and stacking discrete materials, has shown significant benefits in fabrication complicated implants for tissue engineering (TE). However, many native tissues exhibit anisotropic heterogenous constructs with diverse components functions. Consequently, replication biomimetic using conventional AM processes a single material challenging. Multimaterial 3D 4D bioprinting (with time as fourth dimension) emerged promising solution constructing multifunctional that can mimic host microenvironment better than single-material alternatives. Notably, 4D-printed multimaterial architectures provide time-dependent programmable dynamic promote cell activity regeneration response to external stimuli. This paper first presents typical design strategies TE applications. Subsequently, latest are discussed, along their advantages challenges. In particular, potential smart highlighted. Furthermore, this review provides insights into how facilitate realization next-generation

Language: Английский

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Recent Advances in 3D Printing of Smart Scaffolds for Bone Tissue Engineering and Regeneration

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(34)

Published: June 11, 2024

The repair and functional reconstruction of bone defects resulting from severe trauma, surgical resection, degenerative disease, congenital malformation pose significant clinical challenges. Bone tissue engineering (BTE) holds immense potential in treating these defects, without incurring prevalent complications associated with conventional autologous or allogeneic grafts. 3D printing technology enables control over architectural structures at multiple length scales has been extensively employed to process biomimetic scaffolds for BTE. In contrast inert grafts, next-generation smart possess a remarkable ability mimic the dynamic nature native extracellular matrix (ECM), thereby facilitating regeneration. Additionally, they can generate tailored controllable therapeutic effects, such as antibacterial antitumor properties, response exogenous and/or endogenous stimuli. This review provides comprehensive assessment progress 3D-printed BTE applications. It begins an introduction physiology, followed by overview technologies utilized scaffolds. Notable advances various stimuli-responsive strategies, efficacy, applications are discussed. Finally, highlights existing challenges development implementation scaffolds, well emerging this field.

Language: Английский

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A review of 4D printing – Technologies, shape shifting, smart polymer based materials, and biomedical applications

Advanced Industrial and Engineering Polymer Research, Journal Year: 2023, Volume and Issue: 7(1), P. 20 - 36

Published: Aug. 19, 2023

Additive Manufacturing (AM) has been a noticeable technology and made significant progress since the late 1980s. Despite tremendous growth, this is still facing numerous manufacturing challenges. AM of smart materials structures one most actively researched areas in which printed objects can alter their properties shape when expose to stimulus e.g., light, temperature, magnetic fields, pH, humidity. The AM-build parts take advantage these shape-changing features, lead growth 4D printing by introducing time as fourth dimension processes. This new filed originated 2013, then, it generated great interest due its potential build innovative, multi-functional, self-assembling, self-repairing components with modifiable properties, shapes, functionalities. review article intends examine major developments biomedical field. study will provide an overview various technologies uses field, including vat photo-polymerization, extrusion-based methods, material jetting. It focuses on applications industries mechanical, biomedical, aerospace, etc., explores external stimuli such moisture, light. delves into promising fields drug delivery, orthopedics, medical devices, tissue engineering, dentistry analyzes challenges associated suggests future directions optimization parameters, exploration novel broaden applications.

Language: Английский

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