Coordination Chemistry Reviews, Journal Year: 2023, Volume and Issue: 490, P. 215209 - 215209
Published: May 18, 2023
Language: Английский
Advanced Materials, Journal Year: 2023, Volume and Issue: 35(52)
Published: June 26, 2023
Recent developments in wearable and implanted devices have resulted numerous, unprecedented capabilities that generate increasingly detailed information about a user's health or provide targeted therapy. However, options for powering such systems remain limited to conventional batteries which are large toxic components as not suitable close integration with the human body. This work provides an in-depth overview of biofluid-activated electrochemical energy devices, emerging class sources judiciously designed biomedical applications. These unconventional composed biocompatible materials harness inherent chemistries various biofluids produce useable electrical energy. covers examples form biofuel cells, batteries, supercapacitors. Advances materials, design engineering, biotechnology basis high-performance, discussed. Innovations hybrid manufacturing heterogeneous device maximize power output also included. Finally, key challenges future scopes this nascent field provided.
Language: Английский
Citations
63
Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown
Published: May 14, 2024
Abstract Electrochemical (EC) analysis has emerged as a high‐sensitivity, reliable, cost‐effective, and rapidly evolving technique that garnered significant attention across diverse domains. Furthermore, EC‐based techniques hold great potential for miniaturization integration. The integration of EC with mode/signal (such light, magnetic, thermal signals, etc.) provides unique opportunities biosensors to acquire more information through single sensing platform. By coupling multiple signals or processing them logically, the detection accuracy can be further improved, probability false positives negatives minimized. In this review, thorough multi‐ sensors in field is conducted, along their various (e.g., fluorescence, photothermal, colorimetry, microfluidic, etc.). aim delve into latest advances, applications, well challenges multi‐mode/signal biosensors, where utilization modalities helps enhance accuracy, sensitivity, selectivity. This review new insight synergistic effects integrating other techniques, aiming shed light on near‐future developments EC‐integrated biosensors.
Language: Английский
Citations
30
Biosensors, Journal Year: 2022, Volume and Issue: 12(8), P. 583 - 583
Published: July 29, 2022
Many emerging technologies have the potential to improve health care by providing more personalized approaches or early diagnostic methods. In this review, we cover smartphone-based multiplexed sensors as affordable and portable sensing platforms for point-of-care devices. Multiplexing has been gaining attention recently clinical diagnosis considering certain diseases require analysis of complex biological networks instead single-marker analysis. Smartphones offer tremendous possibilities on-site detection due their portability, high accessibility, fast sample processing, robust imaging capabilities. Straightforward digital convenient user interfaces support networked systems individualized monitoring. Detailed biomarker profiling provides accurate disease limited volume collection. Here, assays with optical electrochemical components are covered. Possible wireless wired communication actuators wearable integration various applications discussed. The crucial features weaknesses these devices critically evaluated.
Language: Английский
Citations
50
Analytical Chemistry, Journal Year: 2023, Volume and Issue: 95(10), P. 4753 - 4759
Published: Feb. 27, 2023
The COVID-19 crisis requires fast and highly sensitive tests for the early stage detection of SARS-CoV-2 virus. For detecting nucleocapsid protein (N protein), most abundant viral antigen, we have employed upconversion nanoparticles that emit short-wavelength light under near-infrared excitation (976 nm). anti-Stokes emission avoids autofluorescence scattering thus enables measurements without optical background interference. sandwich upconversion-linked immunosorbent assay (ULISA) can be operated both in a conventional analog mode digital based on counting individual immune complexes. We investigated how different antibody combinations affect wildtype N (alpha variant) lysed culture fluid via protein. ULISA yielded limit (LOD) 1.3 pg/mL (27 fM) independent or readout, which is approximately 3 orders magnitude more than enzyme-linked assays commercial lateral flow home testing. In case SARS-CoV-2, additionally improved LOD by factor 10 compared to readout.
Language: Английский
Citations
35
ACS Sensors, Journal Year: 2023, Volume and Issue: 8(12), P. 4420 - 4441
Published: Nov. 18, 2023
CRISPR/Cas system is becoming an increasingly influential technology that has been repositioned in nucleic acid detection. A preamplification step usually required to improve the sensitivity of CRISPR/Cas-based The striking biological features CRISPR/Cas, including programmability, high and sequence specificity, single-base resolution. More strikingly, target-activated trans-cleavage could act as a biocatalytic signal transductor amplifier, thereby empowering it potentially perform detection without step. reports such work are on rise, which not only scientifically significant but also promising for futuristic end-user applications. This review started with introduction methods acids diagnostics (CRISPR-Dx). Next, we objectively discussed pros cons steps CRISPR-Dx. We then illustrated highlighted recently developed strategies CRISPR/Cas-powered amplification-free can be realized through uses ultralocalized reactors, cascade reactions, ultrasensitive systems, or others. Lastly, challenges perspectives were proposed. It expected this makes researchers better understand current emerging field, provides insight designing novel CRISPR-Dx win practicable use near future.
Language: Английский
Citations
34
Heliyon, Journal Year: 2023, Volume and Issue: 9(3), P. e13986 - e13986
Published: Feb. 24, 2023
Pesticide usage has increased to fulfil agricultural demand. Pesticides such as organophosphorus pesticides (OPPs) are ubiquitous in world food production. Their widespread unavoidable detrimental consequences for humans, wildlife, water, and soil environments. Hence, the development of more convenient efficient pesticide residue (PR) detection methods is paramount importance. Visual detecting approaches have acquired a lot interest among different sensing systems due inherent advantages terms simplicity, speed, sensitivity, eco-friendliness. Furthermore, various detections been proven enable real-life PR surveillance environment water. Fluorometric (FL), colourimetric (CL), enzyme-inhibition (EI) techniques emerged viable options. These technologies do not need complex operating processes or specialist equipment, simple colour change allows visual monitoring result. on-site water environments discussed this paper. This paper further reviews prior research on integration CL, FL, EI-based with nanoparticles (NPs), quantum dots (QDs), metal-organic frameworks (MOFs). Smartphone PRs also reviewed. Finally, conventional nanoparticle (NPs) based strategies compared.
Language: Английский
Citations
29
Talanta, Journal Year: 2023, Volume and Issue: 267, P. 125259 - 125259
Published: Oct. 2, 2023
Language: Английский
Citations
26
Advanced Materials, Journal Year: 2023, Volume and Issue: 36(3)
Published: Dec. 2, 2023
Abstract Advances in the development of new biorecognition elements, nanoparticle‐based labels as well instrumentation have inspired design bioaffinity assays. This review critically discusses potential nanoparticles to replace current enzymatic or molecular immunoassays and other Successful implementations commercial assays need for rapid tests incorporating different roles such capture support, signal generation amplification systems are highlighted. The limited number applied can be explained by challenges associated with analysis real samples (e.g., blood, urine, nasal swabs) that difficult resolve, particularly if same performance achieved more easily conventional labels. Lateral flow based on visual detection red‐colored line formed colloidal gold a notable exception, exemplified SARS‐CoV‐2 antigen moved from initial laboratory testing widespread market adaption less than two years.
Language: Английский
Citations
26
Journal of Agricultural and Food Chemistry, Journal Year: 2023, Volume and Issue: 71(8), P. 3551 - 3563
Published: Jan. 19, 2023
Foodborne viruses have been recognized as important threats to food safety and human health. Rapid accurate detection is one of the most crucial measures for control. With development biology, chemistry, nanoscience, related interdisciplines, strategies devised advanced continuously. This review mainly focuses on progress methods foodborne viruses. The current are summarized, including traditional electron microscopy cultural isolation, immunoassay, molecular technology, biosensors, newly emerging CRISPR/Cas-based technology. Furthermore, a comparison was objectively discussed. provides comprehensive account virus from fundamentals state-of-the-art illustrates advantages disadvantages proposes future trends directions detection. It hoped that this can update knowledge present blueprints in order accelerate futuristic development.
Language: Английский
Citations
24
Biosensors and Bioelectronics, Journal Year: 2023, Volume and Issue: 236, P. 115426 - 115426
Published: May 25, 2023
Language: Английский
Citations
24