Light‐up the white light emission in microscale with a superior deep‐blue AIE fiber as wave‐guiding source DOI Creative Commons

Hao Rao,

Zicheng Liu, Ming Chen

et al.

Aggregate, Journal Year: 2023, Volume and Issue: 5(2)

Published: Nov. 1, 2023

Abstract The development of high‐performance organic blue light‐emitting emitters is in urgent to act as an excitation source contribute the white light generation. On other hand, investigation on optical waveguides have been received increasing attentions because they can manipulate propagation accurately microscale boost optoelectronic and energy conversion applications. In this work, we facilely prepared a deep‐blue aggregation‐induced emission (AIE) dye, namely TPP‐4OMe, which shows high luminescent efficiency, narrow band good stability aggregate state. TPP‐4OMe be fabricated AIE microfibers readily with definite morphology composition. Based microfibers, active waveguide transmit signals achieved very low loss coefficient ( α ) 6.7 × 10 −3 dB μm −1 . Meanwhile, full‐visible broadband low‐loss passive well performed these has never observed pure crystals. More interestingly, excellent properties enable them wave‐guiding source, resulting distinct emission. present work not only provides materials but also bridges realize efficient accelerate practical

Language: Английский

Photothermal Nanomaterials: A Powerful Light-to-Heat Converter DOI Creative Commons
Ximin Cui, Qifeng Ruan, Xiaolu Zhuo

et al.

Chemical Reviews, Journal Year: 2023, Volume and Issue: 123(11), P. 6891 - 6952

Published: May 3, 2023

All forms of energy follow the law conservation energy, by which they can be neither created nor destroyed. Light-to-heat conversion as a traditional yet constantly evolving means converting light into thermal has been enduring appeal to researchers and public. With continuous development advanced nanotechnologies, variety photothermal nanomaterials have endowed with excellent harvesting capabilities for exploring fascinating prospective applications. Herein we review latest progresses on nanomaterials, focus their underlying mechanisms powerful light-to-heat converters. We present an extensive catalogue nanostructured materials, including metallic/semiconductor structures, carbon organic polymers, two-dimensional materials. The proper material selection rational structural design improving performance are then discussed. also provide representative overview techniques probing photothermally generated heat at nanoscale. finally recent significant developments applications give brief outlook current challenges future directions nanomaterials.

Language: Английский

Citations

772

Aggregation-Induced Emission (AIE), Life and Health DOI Creative Commons
Haoran Wang, Qiyao Li, Parvej Alam

et al.

ACS Nano, Journal Year: 2023, Volume and Issue: 17(15), P. 14347 - 14405

Published: July 24, 2023

Light has profoundly impacted modern medicine and healthcare, with numerous luminescent agents imaging techniques currently being used to assess health treat diseases. As an emerging concept in luminescence, aggregation-induced emission (AIE) shown great potential biological applications due its advantages terms of brightness, biocompatibility, photostability, positive correlation concentration. This review provides a comprehensive summary AIE luminogens applied structure dynamic physiological processes, disease diagnosis treatment, detection monitoring specific analytes, followed by representative works. Discussions on critical issues perspectives future directions are also included. aims stimulate the interest researchers from different fields, including chemistry, biology, materials science, medicine, etc., thus promoting development fields life health.

Language: Английский

Citations

189

Nanoparticle‐Based Photothermal Therapy for Breast Cancer Noninvasive Treatment DOI

Yao Xiong,

Yan Rao,

Jiawei Hu

et al.

Advanced Materials, Journal Year: 2023, Volume and Issue: unknown

Published: Aug. 10, 2023

Rapid advancements in materials science and nanotechnology, intertwined with oncology, have positioned photothermal therapy (PTT) as a promising noninvasive treatment strategy for cancer. The breast's superficial anatomical location aesthetic significance render breast cancer particularly pertinent candidate the clinical application of PTT following melanoma. This review comprehensively explores research conducted on various types nanoparticles employed elaborates their specific roles mechanisms action. integration existing therapies is scrutinized, underscoring its potential synergistic outcomes. Additionally, underlying consequential modifications to tumor microenvironment after are elaborated from medical perspective. Future directions suggested, an emphasis development integrative platforms that combine multiple therapeutic approaches optimization nanoparticle synthesis enhanced efficacy. goal push boundaries toward comprehensive, clinically applicable

Language: Английский

Citations

83

NIR-II light in clinical oncology: opportunities and challenges DOI
Zeyu Zhang, Yang Du, Xiaojing Shi

et al.

Nature Reviews Clinical Oncology, Journal Year: 2024, Volume and Issue: 21(6), P. 449 - 467

Published: May 1, 2024

Language: Английский

Citations

82

Chlorination‐Mediated π–π Stacking Enhances the Photodynamic Properties of a NIR‐II Emitting Photosensitizer with Extended Conjugation DOI
Ying Gu, Hanjian Lai, Ziyi Chen

et al.

Angewandte Chemie International Edition, Journal Year: 2023, Volume and Issue: 62(25)

Published: April 20, 2023

NIR-II-emitting photosensitizers (PSs) have attracted great research interest due to their promising clinical applications in imaging-guided photodynamic therapy (PDT). However, it is still challenging realize highly efficient PDT on NIR-II PSs. In this work, we develop a chlorination-mediated π-π organizing strategy improve the of PS with conjugation-extended A-D-A architecture. The significant dipole moment carbon-chlorine bond and strong intermolecular interactions chlorine atoms bring compact stacking chlorine-substituted PS, which facilitates energy/charge transfer promotes photochemical reactions PDT. Consequently, resultant emitting exhibits leading performance yield reactive oxygen species higher than that previously reported long-wavelength These findings will enlighten future design PSs enhanced efficiency.

Language: Английский

Citations

60

Recent advances in fluorescence imaging-guided photothermal therapy and photodynamic therapy for cancer: From near-infrared-I to near-infrared-II DOI

Hangqi Luo,

Shuai Gao

Journal of Controlled Release, Journal Year: 2023, Volume and Issue: 362, P. 425 - 445

Published: Sept. 8, 2023

Language: Английский

Citations

51

Neutral Cyanine: Ultra‐Stable NIR‐II Merocyanines for Highly Efficient Bioimaging and Tumor‐Targeted Phototheranostics DOI
Yingpeng Wan, Weilong Chen,

Ying Liu

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(31)

Published: May 21, 2024

Fluorescence imaging (FLI)-guided phototheranostics using emission from the second near-infrared (NIR-II) window show significant potential for cancer diagnosis and treatment. Clinical imaging-used polymethine ionic indocyanine green (ICG) dye is widely adopted NIR fluorescence imaging-guided photothermal therapy (PTT) research due to its exceptional photophysical properties. However, ICG has limitations such as poor photostability, low conversion efficiency (PCE), short-wavelength peak, liver-targeting issues, which restrict wider use. In this study, two derivatives are transformed into neutral merocyanines (mCy) achieve much-enhanced performance NIR-II phototheranostics. Initial designs of dyes similar drawbacks in terms photostability performance. One modified molecules, mCy890, shows significantly improved stability, an peak over 1000 nm, a high PCE 51%, all considerably outperform ICG. vivo studies demonstrate that nanoparticles mCy890 can effectively accumulate at tumor sites guided by imaging. This provides valuable insights development enhanced

Language: Английский

Citations

24

Recent advances in the design of organic photothermal agents for cancer treatment: A review DOI

Seongman Lee,

Suhong Min,

Gahyun Kim

et al.

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 506, P. 215719 - 215719

Published: Feb. 24, 2024

Language: Английский

Citations

20

A Self-degrading and NIR-II emissive type I/II photosensitizer with synergistic photodynamic and photothermal properties for antibacterial and anticancer DOI
Hongyu Chen, Sijie Yan, Liang Zhang

et al.

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 405, P. 135346 - 135346

Published: Jan. 15, 2024

Language: Английский

Citations

18

Biomedical applications of NIR-II organic small molecule fluorescent probes in different organs DOI
Lizhen Xu, Qian Zhang, Xin Wang

et al.

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 519, P. 216122 - 216122

Published: Aug. 6, 2024

Language: Английский

Citations

18