Chemical Reviews,
Journal Year:
2024,
Volume and Issue:
124(9), P. 5505 - 5616
Published: April 16, 2024
The
recent
emergence
of
nanomedicine
has
revolutionized
the
therapeutic
landscape
and
necessitated
creation
more
sophisticated
drug
delivery
systems.
Polymeric
nanoparticles
sit
at
forefront
numerous
promising
designs,
due
to
their
unmatched
control
over
physiochemical
properties
such
as
size,
shape,
architecture,
charge,
surface
functionality.
Furthermore,
polymeric
have
ability
navigate
various
biological
barriers
precisely
target
specific
sites
within
body,
encapsulate
a
diverse
range
cargo
efficiently
release
this
in
response
internal
external
stimuli.
However,
despite
these
remarkable
advantages,
presence
wider
clinical
application
is
minimal.
This
review
will
provide
comprehensive
understanding
vehicles.
affecting
be
outlined
first,
followed
by
description
nanoparticle
designs
preparation
methods,
beginning
with
polymers
on
which
they
are
based.
meticulously
explore
current
performance
against
myriad
diseases
including
cancer,
viral
bacterial
infections,
before
finally
evaluating
advantages
crucial
challenges
that
determine
potential
decades
come.
Advanced Healthcare Materials,
Journal Year:
2024,
Volume and Issue:
14(4)
Published: Nov. 6, 2024
Cancer
remains
one
of
the
most
challenging
health
issues
globally,
demanding
innovative
therapeutic
approaches
for
effective
treatment.
Nanoparticles,
particularly
those
composed
gold,
silver,
and
iron
oxide,
have
emerged
as
promising
candidates
changing
cancer
therapy.
This
comprehensive
review
demonstrates
landscape
nanoparticle-based
oncological
interventions,
focusing
on
remarkable
advancements
potentials
oxide
nanoparticles.
Gold
nanoparticles
garnered
significant
attention
their
exceptional
biocompatibility,
tunable
surface
chemistry,
distinctive
optical
properties,
rendering
them
ideal
various
diagnostic
strategies.
Silver
nanoparticles,
renowned
antimicrobial
exhibit
potential
in
therapy
through
multiple
mechanisms,
including
apoptosis
induction,
angiogenesis
inhibition,
drug
delivery
enhancement.
With
magnetic
properties
offer
unique
diagnosis
targeted
opportunities.
critically
examines
recent
synthesis,
functionalization,
biomedical
applications
these
Moreover,
challenges
are
discussed,
toxicity
concerns,
immunogenicity,
translational
barriers,
ongoing
efforts
to
overcome
hurdles
highlighted.
Finally,
insights
into
future
directions
regulatory
considerations,
provided
aiming
accelerate
translation
technologies
from
bench
bedside.
RSC Advances,
Journal Year:
2024,
Volume and Issue:
14(16), P. 11594 - 11603
Published: Jan. 1, 2024
Plasmonics
and
core-shell
nanomaterials
hold
great
potential
to
develop
pharmaceuticals
medical
equipment
due
their
eco-friendly
cost
effective
fabrication
procedures.
Despite
these
advancements,
combating
drug-resistant
bacterial
infections
remains
a
global
challenge.
Therefore,
this
study
aims
introduce
tailored
theoretical
framework
for
one-dimensional
(1D)
photonic
crystal
biosensor
(PCB)
composed
of
(ZrO
Langmuir,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 26, 2024
To
form
nonspherical
emulsion
droplets,
the
interfacial
tension
driving
droplet
sphericity
must
be
overcome.
This
can
achieved
through
particle
jamming;
however,
careful
control
of
coverage
is
required.
In
this
work,
we
present
a
scalable
novel
batch
process
to
particle-stabilized
emulsions.
by
concurrently
forming
interfacially
active
particles
and
drastically
accelerating
destabilization
addition
electrolyte.
achieve
this,
surfactant-stabilized
oil-in-water
emulsions
in
presence
dopamine
were
first
produced.
These
then
treated
with
tris(hydroxymethyl)aminomethane
hydrochloride
buffer
both
simultaneously
initiate
polymerization
continuous
phase
reduce
Debye
length
system,
thus
coalescence
while
surface-active
particles.
The
concentration
imposed
shear
was
systematically
varied,
behavior
at
interface
studied
using
pendent
drop
tensiometry
rheology.
It
found
that
polydopamine
nanoparticles
formed
adsorbed
reducing
during
coalescence,
resulting
anisotropic
droplets
via
arrested
coalescence.
Greater
rates
resulted
accelerated
formation
secondary
whereas
lower
thicker
films.
efficacy
method
further
demonstrated
second
system
consisting
sodium
dodecyl
sulfate
as
surfactant
polypyrrole
particles,
which
also
for
optimized
conditions.
RSC Applied Polymers,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 1, 2024
Synthetic
imitation
of
nonspherical
microorganisms
can
enhance
therapeutic
delivery
in
the
body.
Hydrogel
microcapsules
with
bacteria-mimicking
shapes
were
synthesized
through
a
multilayer
assembly
polymers
on
sacrificial
microparticle
surfaces.
