Journal of Controlled Release, Journal Year: 2021, Volume and Issue: 332, P. 269 - 284
Published: March 1, 2021
Language: Английский
Advanced Materials, Journal Year: 2021, Volume and Issue: 33(21)
Published: April 19, 2021
Abstract Pancreatic cancer, one of the most lethal malignancies, compromises performance traditional therapeutic regimens in clinic because stromal resistance to systemic drug delivery and poor prognosis caused by tumor metastasis. Therefore, a biocompatible paradigm that can effectively inhibit pancreatic growth while simultaneously eliminating metastasis is urgently needed. Herein, supramolecular nanofibrils are fabricated through coassembly clinically approved immunomodulatory thymopentin near‐infrared indocyanine green for localized photothermal immunotherapy tumors. The resulting long‐range ordered fibrous nanodrugs show improved photophysical capabilities fluorescence imaging conversion significantly promote proliferation differentiation antitumor immune cells. Hence, integration rapid therapy moderate immunomodulation inhibiting promising. utilization molecules construct administered via injection amplifies complementary immunotherapeutic effects components, creating opportunities clinical translation as treatment cancer.
Language: Английский
Citations
153
Coordination Chemistry Reviews, Journal Year: 2022, Volume and Issue: 469, P. 214687 - 214687
Published: June 27, 2022
Language: Английский
Citations
149
Nature Reviews Clinical Oncology, Journal Year: 2023, Volume and Issue: 20(2), P. 116 - 134
Published: Jan. 5, 2023
Language: Английский
Citations
145
Coordination Chemistry Reviews, Journal Year: 2021, Volume and Issue: 451, P. 214267 - 214267
Published: Nov. 6, 2021
Language: Английский
Citations
140
Journal of Controlled Release, Journal Year: 2021, Volume and Issue: 332, P. 269 - 284
Published: March 1, 2021
Language: Английский
Citations
127