Expert Opinion on Drug Delivery,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 17, 2024
Introduction
Chiral
nanocarriers
enhance
therapeutic
efficacy
by
improving
in
vivo
stability
and
cellular
uptake.
Chemical
functionalization
reduces
cytotoxicity,
resulting
favorable
biocompatibility.
Nanoparticles
self-assemble
into
supraparticles,
enhancing
drug
delivery
through
improved
retention
loading.
Area
covered
This
review
covers
chiral
nanostructures
their
mechanisms,
applications
various
healthcare
applications.
Expert
Opinion
The
chirality
of
biomaterials
is
crucial
for
advancing
nanomedicine.
nanosystem
interacting
selectively
with
biological
molecules,
specificity
efficacy.
off-target
effects
improves
outcomes.
Research
has
focused
on
uptake
elimination
to
ensure
safety,
nanomaterials
also
show
promise
optical
sensing
gene
editing.
Their
biocompatibility
ability
supraparticles
may
make
them
ideal
systems.
Advanced Science,
Journal Year:
2024,
Volume and Issue:
11(13)
Published: Jan. 24, 2024
Chiral
CDots
(c-CDots)
not
only
inherit
those
merits
from
but
also
exhibit
chiral
effects
in
optical,
electric,
and
bio-properties.
Therefore,
c-CDots
have
received
significant
interest
a
wide
range
of
research
communities
including
chemistry,
physics,
biology,
device
engineers.
They
already
made
decent
progress
terms
synthesis,
together
with
the
exploration
their
optical
properties
applications.
In
this
review,
chiroptical
chirality
origin
extinction
circular
dichroism
(ECD)
circularly
polarized
luminescence
(CPL)
is
briefly
discussed.
Then,
synthetic
strategies
summarized,
one-pot
post-functionalization
ligands,
assembly
into
architectures
soft
templates.
Afterward,
on
applications
are
elaborated.
Research
domains
such
as
drug
delivery,
bio-
or
chemical
sensing,
regulation
enzyme-like
catalysis,
others
covered.
Finally,
perspective
challenges
associated
strategies,
understanding
chirality,
potential
provided.
This
review
discusses
latest
developments
helps
toward
better
structure-property
relationship
along
respective
Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
34(38)
Published: April 30, 2024
Abstract
Microbial
infections
pose
a
significant
threat
to
public
health,
exacerbated
by
the
escalating
issue
of
antibiotic
resistance
resulting
from
their
overuse.
Chiral
carbon
dots
(CDs)
not
only
inherit
antibacterial
properties
CDs
but
also
demonstrate
highly
selective
chiral
bactericidal
activity.
This
study
focuses
on
development
synthesized
D‐
and
L‐cysteine,
selectively
identify
synergistically
eradicate
Gram‐positive
bacteria
fungi.
exhibit
high
efficacy
in
staining
fungi
while
demonstrating
minimal
no
fluorescence
with
Gram‐negative
bacteria,
attributable
variances
membrane
structures
these
pathogens.
D‐CDs
stronger
signals
greater
against
compared
L‐CDs.
Under
dual
light
irradiation,
bolster
activity
through
triple‐modal
mechanism,
involving
disruption
absence
light,
singlet
oxygen
generation
during
photodynamic
therapy,
elevated
temperature
photothermal
treatment.
Animal
studies
additionally
showcase
that
notably
enhanced
healing
wounds
infected
S.
aureus
under
laser
exposure.
investigation
underscores
chiral‐specific
imaging
potentials
D‐CDs,
paving
way
for
advancement
nanomaterials
bacterial
diagnostics
therapy.
Dalton Transactions,
Journal Year:
2024,
Volume and Issue:
53(29), P. 12281 - 12290
Published: Jan. 1, 2024
Silver
nanoparticles
(Ag
NPs)
exhibit
strong
antibacterial
activity
and
are
widely
used
in
industries
such
as
medical,
food
cosmetics.
In
this
study,
Ag
nanospheres
nanotriangles
selected
agents
to
reveal
the
distinct
mechanism
of
tip
effects
towards
their
performance.
A
series
experiments
were
implemented,
including
Angewandte Chemie International Edition,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 16, 2024
Abstract
Circularly
polarized
luminescence
(CPL)
has
numerous
applications
in
optical
data
storage,
quantum
computing,
bioresponsive
imaging,
liquid
crystal
displays,
and
backlights
three‐dimensional
(3D)
displays.
In
addition
to
their
competitive
properties,
carbon
dots
(CDs)
benefit
from
simple
low‐cost
preparation,
facile
post‐modification,
excellent
resistance
photo‐
chemical
bleaching
after
carbonization.
Combining
the
superior
performance
with
polarization
peculiarities
through
hierarchical
structure
engineering
is
imperative
for
development
of
CDs.
this
study,
hydrophobic
interactions
aromatic
ligands,
which
participate
surface‐ligand
post‐modification
process
on
ground‐state
chiral
core,
are
employed
drive
oriented
assembly.
Furthermore,
residual
amides
CDs
form
multiple
hydrogen
bonds
during
gradual
aggregation,
causing
assembled
materials
an
asymmetric
bending
structure.
Superficial
ligands
interfere
dynamics
exciton
radiation
transition
stabilize
excited
state
achieve
a
circularly
signal.
The
linkage
overcome
frequent
aggregation‐induced
quenching
phenomenon
that
present
difficulties
conventional
CDs,
facilitate
assembly
self‐supporting
films,
improve
expression.
full‐color
white
CPL
manipulated
by
simply
adjusting
functional
groups
also
illustrates
versatility
strategy.
Finally,
large
flexible
films
multicolor
light‐emitting
diodes
based
stable
powder
phosphors
were
constructed,
thereby
providing
feasible
technical
support
3D
Advanced Optical Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 21, 2025
Abstract
The
fabrication
of
discrete
chiral
Au
nanorods
(c‐Au
NRs)
used
as
new
emerging
plasmonic
nanozyme
for
colorimetric
detection
glucose
is
presented.
It
found
that
the
based
on
c‐Au
NRs
dependent
geometries
and
polarized
light.
In
comparison
to
Lc‐Au
NRs,
Dc‐Au
possess
a
lower
linear
concentration
range
limit
(LOD)
due
their
higher
affinity
capacity.
More
importantly,
light
(LP:
linearly
light;
LCP:
left‐handed
circularly
RCP:
right‐handed
light)
can
enantioselectively
markedly
improve
LOD
hot
electrons
electromagnetic
field.
For
instance,
under
RCP
irradiation
in
LCP
irradiation.
Similarly,
than
Our
work
not
only
provides
novel
strategy
levels,
but
also
reveals
interaction
between
matters
chemical
substrates,
which
will
be
helpful
field
recognition,
catalysis,
drugs.
Nano Letters,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 28, 2025
Carbon
dots
(CDs)
with
circularly
polarized
long
afterglow
(CPLA)
properties
have
received
increasing
attention
as
a
cutting-edge
research
field.
However,
because
the
CDs
both
and
chirality
are
difficult
to
prepare
color
of
most
phosphorescent
is
mainly
concentrated
in
short
wavelengths,
it
still
formidable
challenge
explore
facile
route
achieve
intrinsic
CD-based
color-tunable
CPLA
materials
on
large
scale.
Herein,
we
developed
gram-scale
synthesis
method
via
simple
hydrothermal
mixture
boric
acid,
arginine,
various
fluorescent
dyes.
The
tunable
successfully
achieved
by
engineering
situ
phosphorescence
resonance
energy
transfer
(PRET)
between
formed
carbonization
arginine
some
dyes
those
uncarbonized
Finally,
applications
CD
composites
multimode
advanced
anti-counterfeiting
information
encryption
were
explored.
Advanced Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 11, 2025
Abstract
Biological
lasers,
representing
innovative
miniaturized
laser
technology,
hold
immense
potential
in
the
fields
of
biological
imaging,
detection,
sensing,
and
medical
treatment.
However,
reported
gain
media
for
lasers
encounter
several
challenges
complex
preparation
procedures,
high
cost,
toxicity
concerns,
limited
biocompatibility,
stability
issues
along
with
poor
processability
tunability.
These
drawbacks
have
impeded
sustainable
development
lasers.
Carbon
dots
(CDs),
as
a
novel
solution‐processable
materials
characterized
by
facile
preparation,
low
toxicity,
excellent
stability,
easy
modification,
luminescence
tuning
capabilities
outstanding
performance.
Consequently,
they
find
extensive
applications
diverse
such
biology,
photoelectricity,
Henceforth,
are
particularly
suitable
constructing
This
paper
provides
comprehensive
review
on
classification
application
existing
while
emphasizing
advantages
CDs
compared
to
other
media.
Furthermore,
it
presents
latest
progress
made
utilizing
forecasts
both
promising
prospects
based
CDs.
study
aims
enhance
understanding
CD
foster
advancements
field
