European Journal of Organic Chemistry,
Journal Year:
2022,
Volume and Issue:
2022(8)
Published: Jan. 11, 2022
Abstract
In
the
pursuit
of
clean
pharmaceutical
production,
chemists
in
medicinal
industry
require
access
to
new
sustainable
methodologies
reduce
and
even
eliminate
pollution,
which
is
mainly
produced
by
overuse
organic
solvents
during
chemical
synthesis
active
ingredients
(APIs).
this
context,
solvent‐free/less
mechanochemical
functionalization
small
molecules
has
gradually
emerged
as
a
powerful
strategy
for
green
modification
APIs,
bioactive
compounds,
functional
materials.
review,
we
present
an
overview
C−X/C−H
applications
chemistry,
involving
cross‐coupling,
cross‐dehydrogenative
coupling,
oxidative
coupling
(via
C−H
activation
pathway),
direct
radical
pathway)
key
steps
preparation
APIs
compounds.
Angewandte Chemie International Edition,
Journal Year:
2020,
Volume and Issue:
59(36), P. 15402 - 15423
Published: March 11, 2020
Abstract
Increasing
the
stream
of
recycled
plastic
necessitates
an
approach
beyond
traditional
recycling
via
melting
and
re‐extrusion.
Various
chemical
processes
have
great
potential
to
enhance
rates.
In
this
Review,
a
summary
various
routes
assessment
life‐cycle
analysis
is
complemented
by
extensive
list
developed
companies
active
in
recycling.
We
show
that
each
currently
available
applicable
for
specific
waste
streams.
Thus,
only
combination
different
technologies
can
address
problem.
Research
should
focus
on
more
realistic,
contaminated
mixed
streams,
while
collection
sorting
infrastructure
will
need
be
improved,
is,
stricter
regulation.
This
Review
aims
inspire
both
science
innovation
production
higher
value
quality
products
from
suitable
reuse
or
valorization
create
necessary
economic
environmental
push
circular
economy.
ChemSusChem,
Journal Year:
2021,
Volume and Issue:
14(10), P. 2145 - 2162
Published: April 9, 2021
In
recent
years,
mechanochemistry
has
been
growing
into
a
widely
accepted
alternative
for
chemical
synthesis.
addition
to
their
efficiency
and
practicality,
mechanochemical
reactions
are
also
recognized
sustainability.
The
association
between
Green
Chemistry
often
originates
from
the
solvent-free
nature
of
most
protocols,
which
can
reduce
waste
production.
However,
satisfies
more
than
one
Principles
Chemistry.
this
Review
we
will
present
series
examples
that
clearly
illustrate
how
significantly
contribute
fulfillment
in
holistic
manner.
ACS Catalysis,
Journal Year:
2020,
Volume and Issue:
10(15), P. 8344 - 8394
Published: May 27, 2020
The
extraordinary
impact
of
metal-based
complexes
on
synthetic
methods
is
still
recognized
nowadays,
and
attempts
are
currently
undertaken
to
further
extend
the
use
metal-assisted
chemistry
environmentally
friendly
processes
within
strongly
invoked
green
paradigm.
In
recent
years,
mechanochemistry
seems
provide
attractive
responses
with
processing
having
origins
lost
in
mists
time.
Focusing
panorama
organic
synthesis,
this
Review
highlights
some
recently
developed
mechanochemical
reactions
introduce
reader
into
fascinating,
quite
unexplored
world
mechanochemistry.
Advanced Synthesis & Catalysis,
Journal Year:
2021,
Volume and Issue:
363(5), P. 1246 - 1271
Published: Jan. 21, 2021
Abstract
Mechanochemical
reactions
by
milling,
grinding
or
other
types
of
mechanical
action
have
emerged
as
a
salient
green
approach
because
its
wide
applications
towards
academic
and
industrial
chemical
communities
in
sustainable
solvent‐free/solvent‐less
processes.
Liquid‐assisted
(LAG)
an
extension
traditional
solvent‐free
mechanochemical
techniques
which
small
amount
liquid
is
used
additive
to
enhance
and/or
control
reactivity,
has
been
fruitfully
applied
the
screening
inclusion
compounds,
cocrystals,
salts,
solvates,
polymorphs.
However,
utilization
this
important
technique
synthesis
pharmaceutically
biologically
relevant
targets
was
not
adequately
investigated.
This
review
article
summarizes
overview
latest
development
LAG
approaches
active
pharmaceutical
ingredients
(API)
drug‐like
fragments,
highlights
superiority
versus
conventional
syntheses.
magnified
image
Advanced Materials,
Journal Year:
2022,
Volume and Issue:
34(46)
Published: Jan. 11, 2022
Abstract
Mechanochemistry
with
solvent‐free
and
environmentally
friendly
characteristics
is
one
of
the
most
promising
alternatives
to
traditional
liquid‐phase‐based
reactions,
demonstrating
epoch‐making
significance
in
realization
different
types
chemistry.
utilizes
mechanical
energy
promote
physical
chemical
transformations
design
complex
molecules
nanostructured
materials,
encourage
dispersion
recombination
multiphase
components,
accelerate
reaction
rates
efficiencies
via
highly
reactive
surfaces.
In
particular,
mechanochemistry
deserves
special
attention
because
it
capable
endowing
materials
unique
properties.
Herein,
latest
advances
progress
for
preparation
modification
are
reviewed.
An
outline
basic
knowledge,
methods,
mechanochemical
strategies
presented,
distinguishing
this
review
from
reviews
that
only
focus
on
ball‐milling.
Next,
followed
by
a
detailed
insightful
discussion
mechanochemistry‐involved
conversion
storage
applications.
The
comprehensively
covers
aspects
mechanical/optical/chemical
electrical
energy.
Finally,
next‐generation
advanced
proposed.
This
intended
bring
frontline
guide
burgeoning
field
interdisciplinary
research
developing
greener
force.
Chemistry - A European Journal,
Journal Year:
2021,
Volume and Issue:
27(38), P. 9721 - 9726
Published: April 1, 2021
Abstract
Recent
research
endeavors
have
established
that
the
mechanochemical
activation
of
piezoelectric
materials
can
open
new
avenues
in
redox
chemistry.
Impact
forces,
such
as
those
imparted
by
a
ball
mill,
been
shown
to
transform
barium
titanate
(BaTiO
3
)
into
highly
polarized
state,
which
then
donate
an
electron
suitable
oxidant
and
receive
from
reductant,
mimicking
photoredox
catalytic
cycles.
Proof‐of‐concept
studies
elucidated
mechanoredox
chemistry
holds
great
potential
sustainable
efficient
radical‐based
synthesis.
Angewandte Chemie International Edition,
Journal Year:
2022,
Volume and Issue:
61(37)
Published: July 5, 2022
Ionic
liquids
(ILs)
and
deep
eutectic
solvents
(DESs)
debuted
with
a
promise
of
superior
sustainability
footprint
due
to
their
low
vapor
pressure.
However,
toxicity
high
cost
compromise
this
footprint,
impeding
real-world
applications.
Fortunately,
property
tunability
through
rational
selection
precursors,
including
bioderived
ones,
provides
strategy
ameliorate
toxicity,
lower
cost,
endow
new
functions.
This
Review
discusses
whether
ILs
DESs
are
sustainable
how
they
contribute
chemical
processes.
Green Chemistry,
Journal Year:
2024,
Volume and Issue:
26(8), P. 4270 - 4357
Published: Jan. 1, 2024
Given
the
high
toxicity
of
inorganic
inhibitors,
organic
substances,
primarily
heterocycles,
have
been
proven
to
be
one
most
efficient,
cost-effective,
and
practical
alternatives.
Advanced Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 27, 2024
Sodium-ion
batteries
(SIBs),
recognized
for
balanced
energy
density
and
cost-effectiveness,
are
positioned
as
a
promising
complement
to
lithium-ion
(LIBs)
substitute
lead-acid
batteries,
particularly
in
low-speed
electric
vehicles
large-scale
storage.
Despite
their
extensive
potential,
concerns
about
range
anxiety
due
lower
underscore
the
importance
of
fast-charging
technologies,
which
drives
exploration
high-rate
electrode
materials.
Polyanionic
cathode
materials
emerging
candidates
this
regard.
However,
intrinsic
limitation
electronic
conductivity
poses
challenges
synchronized
electron
ion
transport,
hindering
suitability
applications.
This
review
provides
comprehensive
analysis
sodium
migration
during
charging/discharging,
highlighting
it
critical
rate-limiting
step
fast
charging.
By
delving
into
dynamics,
key
factors
that
constrain
characteristics
identified
summarized.
Innovative
modification
routes
then
introduced,
with
focus
on
shortening
paths
increasing
diffusion
coefficients,
providing
detailed
insights
feasible
strategies.
Moreover,
discussion
extends
beyond
half
cells
full
cells,
addressing
opportunities
transitioning
polyanionic
from
laboratory
practical
aims
offer
valuable
development
cathodes,
acknowledging
pivotal
role
advancing
SIBs.
Angewandte Chemie International Edition,
Journal Year:
2020,
Volume and Issue:
59(50), P. 22570 - 22576
Published: Sept. 14, 2020
Abstract
The
application
of
piezoelectricity
for
the
generation
trifluoromethyl
(CF
3
)
radicals
is
reported
together
with
development
a
method
mechanochemical
C−H
trifluoromethylation
aromatic
compounds.
As
compared
to
conventional
solution‐based
approaches,
this
mechanoredox
enables
cleaner
and
more
sustainable
access
wide
range
trifluoromethylated
N‐heterocycles
peptides,
which
are
important
structural
motifs
in
modern
drug
discovery.
This
study
thus
represents
an
milestone
future
applications
systems
medicinal
pharmaceutical
science.
