Nanomaterials,
Journal Year:
2024,
Volume and Issue:
14(3), P. 244 - 244
Published: Jan. 23, 2024
A
nanozyme
is
a
nanoscale
material
having
enzyme-like
properties.
It
exhibits
several
superior
properties,
including
low
preparation
cost,
robust
catalytic
activity,
and
long-term
storage
at
ambient
temperatures.
Moreover,
high
stability
enables
repetitive
use
in
multiple
reactions.
Hence,
it
considered
potential
replacement
for
natural
enzymes.
Enormous
research
interest
nanozymes
the
past
two
decades
has
made
imperative
to
look
better
enzyme-mimicking
materials
biomedical
applications.
Given
this,
on
metal–organic
frameworks
(MOFs)
as
gained
momentum.
MOFs
are
advanced
hybrid
of
inorganic
metal
ions
organic
ligands.
Their
distinct
composition,
adaptable
pore
size,
structural
diversity,
ease
tunability
physicochemical
properties
enable
mimic
activities
act
promising
candidates.
This
review
aims
discuss
recent
advances
development
MOF-based
(MOF-NZs)
highlight
their
applications
field
biomedicine.
Firstly,
different
enzyme-mimetic
exhibited
by
discussed,
insights
given
into
various
strategies
achieve
them.
Modification
functionalization
deliberated
obtain
MOF-NZs
with
enhanced
activity.
Subsequently,
biosensing
therapeutics
domain
discussed.
Finally,
concluded
giving
challenges
encountered
possible
directions
overcome
them
future.
With
this
review,
we
aim
encourage
consolidated
efforts
across
enzyme
engineering,
nanotechnology,
science,
biomedicine
disciplines
inspire
exciting
innovations
emerging
yet
field.