Micromachines,
Journal Year:
2024,
Volume and Issue:
15(10), P. 1226 - 1226
Published: Sept. 30, 2024
Non-invasive
medical
nanofiber
technology,
characterized
by
its
high
specific
surface
area,
biocompatibility,
and
porosity,
holds
significant
potential
in
various
domains,
including
tissue
repair
biosensing.
It
is
increasingly
becoming
central
to
healthcare
offering
safer
more
efficient
treatment
options
for
contemporary
medicine.
Numerous
studies
have
explored
non-invasive
nanofibers
recent
years,
yet
a
comprehensive
overview
of
the
field
remains
lacking.
In
this
paper,
we
provide
summary
applications
electrospun
fields,
considering
multiple
aspects
perspectives.
Initially,
introduce
electrospinning
nanofibers.
Subsequently,
detail
their
health,
health
monitoring,
personal
protection,
thermal
regulation,
wound
care,
highlighting
critical
role
improving
human
health.
Lastly,
paper
discusses
current
challenges
associated
with
offers
insights
into
future
development
trajectories.
International Journal of Molecular Sciences,
Journal Year:
2021,
Volume and Issue:
22(20), P. 11248 - 11248
Published: Oct. 18, 2021
Parkinson’s
disease
(PD)
is
a
slowly
progressive
multisystem
disorder
affecting
dopaminergic
neurons
of
the
substantia
nigra
pars
compacta
(SNpc),
which
characterized
by
decrease
dopamine
(DA)
in
their
striatal
terminals.
Treatment
PD
with
levodopa
or
DA
receptor
agonists
replaces
function
depleted
striatum.
Prolonged
treatment
these
agents
often
has
variable
therapeutic
effects
and
leads
to
development
undesirable
dyskinesia.
Consequently,
crucial
unmet
demand
management
discovery
new
approaches
that
could
slow
down,
stop,
reverse
process
neurodegeneration.
Novel
potential
treatments
involving
natural
substances
neuroprotective
activities
are
being
developed.
Curcumin
polyphenolic
compound
isolated
from
rhizomes
Curcuma
longa
(turmeric).
It
been
demonstrated
have
potent
anti-inflammatory,
antioxidant,
free
radical
scavenging,
mitochondrial
protecting,
iron-chelating
effects,
considered
promising
nutraceutical
agent
for
PD.
However,
molecular
cellular
mechanisms
mediate
pharmacological
actions
curcumin
remain
largely
unknown.
Stimulation
nicotinic
receptors
and,
more
precisely,
selective
α7
acetylcholine
(α7-nAChR),
found
play
major
modulatory
role
immune
system
via
“cholinergic
anti-inflammatory
pathway”.
Recently,
α7-nAChR
proposed
be
approach
In
this
review,
detailed
as
help
patients
discussed
elaborated
on
detail.
ACS Omega,
Journal Year:
2022,
Volume and Issue:
7(35), P. 30657 - 30672
Published: Aug. 24, 2022
Reactive
oxygen
species
(ROS)
is
considered
a
double-edged
sword.
The
slightly
elevated
level
of
ROS
helps
in
wound
healing
by
inhibiting
microbial
infection.
In
contrast,
excessive
levels
the
site
show
deleterious
effects
on
extending
inflammation
phase.
Understanding
ROS-mediated
molecular
and
biomolecular
mechanisms
their
effect
cellular
homeostasis
thus
substantially
improves
possibility
exogenously
augmenting
manipulating
with
emerging
antioxidant
therapeutics.
This
review
comprehensively
delves
into
relationship
between
critical
phases
processes
underpinning
therapies.
manuscript
also
discusses
cutting-edge
therapeutics
that
act
via
scavenging
to
enhance
chronic
healing.
ACS Applied Materials & Interfaces,
Journal Year:
2022,
Volume and Issue:
14(29), P. 32799 - 32812
Published: July 15, 2022
The
surface
structure
and
topography
of
biomaterials
play
a
crucial
role
in
directing
cell
behaviors
fates.
Meanwhile,
asymmetric
dressings
that
mimic
the
natural
skin
have
been
identified
as
an
effective
strategy
for
enhancing
wound
healing.
Inspired
by
superhydrophobic
lotus
leaf,
composite
dressing
was
obtained
constructing
wettability
modification
on
both
sides
sponge
based
electrospinning.
Among
them,
collagen
quaternized
chitosan
fabricated
freeze-drying,
followed
aligned
poly(ε-caprolactone)
(PCL)/gelatin
nanofiber
hydrophilic
inner
layer
hierarchical
micronanostructure
PCL/polystyrene
microsphere
highly
hydrophobic
outer
constructed
each
side
sponge.
proposed
combines
topological
morphology
with
material's
properties
to
effectively
prevent
bacterial
colonization/infection
promote
healing
cellular
behavior.
In
vitro
experimental
results
confirmed
promotes
adhesion,
proliferation,
directed
growth,
migration.
has
good
water
absorption
antibacterial
properties,
while
biomimetic
exhibits
strong
mechanical
resistance
adhesion.
vivo
showed
can
reduce
inflammatory
response,
infection,
accelerate
angiogenesis
epithelial
regeneration,
significantly
severe
burns.
Thus,
bionic
is
expected
be
promising
candidate
burn
Journal of Applied Polymer Science,
Journal Year:
2023,
Volume and Issue:
141(1)
Published: Oct. 3, 2023
Abstract
In
recent
years,
there
has
been
a
significant
focus
on
bioactive
dressings
suitable
for
treating
chronic
and
acute
wounds.
Electrospinning
nanofibers
are
considered
advanced
dressing
options
due
to
their
high
porosity
permeability
air
water,
effective
barrier
properties
against
external
pathogens,
excellent
resemblance
the
extracellular
matrix
wound
healing
skin
regeneration.
This
article
reviews
advancements
in
application
of
electrospinning
healing.
The
review
begins
with
an
overview
process
methods.
It
then
explores
advantages
disadvantages
different
synthetic
natural
polymers
used
preparation
dressings.
discussed
this
include
collagen,
gelatin,
silk
fibroin,
chitosan,
hyaluronic
acid,
sodium
alginate.
Additionally,
delves
into
commonly
like
polyvinyl
alcohol,
chloride,
polyethylene
lactone,
polylactide,
polyurethane
applications.
Furthermore,
examines
blending
create
high‐performance
also
incorporation
functional
additives,
such
as
antimicrobial
agents,
growth
factors,
extracts,
expedite
tissue
repair.
conclusion,
is
emerging
technology
that
provides
unique
opportunities
designing
more
care
products.
