Alginate composites for bone tissue engineering: A review

International Journal of Biological Macromolecules, Journal Year: 2014, Volume and Issue: 72, P. 269 - 281

Published: July 11, 2014

Language: Английский

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A review of bioactive plant polysaccharides: Biological activities, functionalization, and biomedical applications

Bioactive Carbohydrates and Dietary Fibre, Journal Year: 2014, Volume and Issue: 5(1), P. 31 - 61

Published: Dec. 16, 2014

Language: Английский

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A review of the chemical modification techniques of starch

Carbohydrate Polymers, Journal Year: 2016, Volume and Issue: 157, P. 1226 - 1236

Published: Nov. 3, 2016

Language: Английский

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Fabrication and Characteristics of Chitosan Sponge as a Tissue Engineering Scaffold

BioMed Research International, Journal Year: 2014, Volume and Issue: 2014, P. 1 - 8

Published: Jan. 1, 2014

Cells, growth factors, and scaffolds are the three main factors required to create a tissue-engineered construct. After appearance of bovine spongiform encephalopathy (BSE), considerable attention has therefore been focused on nonbovine materials. In this study, we examined properties chitosan porous scaffold. A sponge was prepared by controlled freezing lyophilization different concentrations solutions. The materials were scanning electron microscopy, porosity, tensile strength, basic fibroblast factor (bFGF) release profiles from in vitro. morphology presented typical microporous structure, with pore size ranging 50 200 μm. porosity approximately 75-85%. decreasing tendency for observed as concentration increased. relationship between indicated that ultimate strength increased higher concentration. vitro bFGF study showed solution became, longer releasing time was.

Language: Английский

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Advances on Bioactive Polysaccharides from Medicinal Plants

Critical Reviews in Food Science and Nutrition, Journal Year: 2015, Volume and Issue: 56(sup1), P. S60 - S84

Published: Oct. 13, 2015

In recent decades, the polysaccharides from medicinal plants have attracted a lot of attention due to their significant bioactivities, such as anti-tumor activity, antioxidant anticoagulant antidiabetic radioprotection effect, anti-viral hypolipidemic and immunomodulatory activities, which make them suitable for applications. Previous studies also shown that plant are non-toxic show no side effects. Based on these encouraging observations, most researches been focusing isolation identification polysaccharides, well bioactivities. A large number bioactive with different structural features biological effects purified characterized. This review provides comprehensive summary developments in physiochemical, activities important plants, Astragalus membranaceus, Dendrobium Bupleurum, Cactus fruits, Acanthopanax senticosus, Angelica sinensis (Oliv.) Diels, Aloe barbadensis Miller, Dimocarpus longan Lour. Moreover, paper has focused applications Recent provided evidence can play vital role The contents data will serve useful reference material further investigation, production, application functional foods therapeutic agents.

Language: Английский

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25th Anniversary Article: Designer Hydrogels for Cell Cultures: A Materials Selection Guide

Advanced Materials, Journal Year: 2013, Volume and Issue: 26(1), P. 125 - 148

Published: Nov. 13, 2013

Cell culturing, whether for tissue engineering or cell biology studies, always involves placing cells in a non‐natural environment and no material currently exist that can mimic the entire complexity of natural tissues variety cell‐matrix interactions is found vivo. Here, we review vast range hydrogels, composed synthetic polymers provide route to tailored microenvironments.

Language: Английский

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Natural Polymeric Scaffolds in Bone Regeneration

Frontiers in Bioengineering and Biotechnology, Journal Year: 2020, Volume and Issue: 8

Published: May 21, 2020

Despite considerable advances in microsurgical techniques over the past decades, bone tissue remains a challenging arena to obtain satisfying functional and structural restoration after damage. Through production of substituting materials mimicking physical biological properties healthy tissue, engineering strategies address an urgent clinical need for therapeutic alternatives autografts. By virtue their versatility, polymers have predominant role generating biodegradable matrices that hold cells situ sustain growth new until integration into transplantation area (i.e., scaffolds). As compared synthetic ones, natural origin generally present superior biocompatibility bioactivity. Their assembly further give rise wide plethora advanced supporting materials, accounting systems based on hydrogels or scaffolds with either fibrous porous architecture. The review offers overview various types currently adopted engineering, describing manufacturing procedures functionalization active biomolecules, listing advantages disadvantages respective use order critically compare actual applicability potential. combination other classes (such as micro nanomaterials) innovative reproduce physiological microenvironments more faithful way are also illustrated. regeneration outcomes achieved vitro vivo when enriched different cell types, well preliminary applications presented, before prospects this research field finally discussed. collection studies herein considered confirms polymer will be determinant designing translatable efficient forthcoming impact expected treatment defects.

Language: Английский

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Decellularized matrices in regenerative medicine

Acta Biomaterialia, Journal Year: 2018, Volume and Issue: 74, P. 74 - 89

Published: April 24, 2018

Language: Английский

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A review on latest innovations in natural gums based hydrogels: Preparations & applications

International Journal of Biological Macromolecules, Journal Year: 2019, Volume and Issue: 136, P. 870 - 890

Published: June 19, 2019

Language: Английский

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Designing Smart Biomaterials for Tissue Engineering

International Journal of Molecular Sciences, Journal Year: 2017, Volume and Issue: 19(1), P. 17 - 17

Published: Dec. 21, 2017

The engineering of human tissues to cure diseases is an interdisciplinary and a very attractive field research both in academia the biotechnology industrial sector. Three-dimensional (3D) biomaterial scaffolds can play critical role development new tissue morphogenesis via interacting with cells. Although simple polymeric biomaterials provide mechanical physical properties required for development, insufficient biomimetic property lack interactions progenitor cells remain problematic promotion functional formation. Therefore, developments advanced that respond stimulus could be next choice generate smart 3D scaffolds, actively stem progenitors along structural integrity form within short period. To date, are designed interact biological systems wide range biomedical applications, from delivery bioactive molecules cell adhesion mediators cellular functioning treat diseases.

Language: Английский

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