UV-Curable Polymer Nanocomposites: Material Selection, Formulations, and Recent Advances DOI Open Access
Mohammad‐Reza Azani, Azin Hassanpour

Journal of Composites Science, Journal Year: 2024, Volume and Issue: 8(11), P. 441 - 441

Published: Oct. 25, 2024

This study addresses the development of UV-curable polymer nanocomposites (PNCs), mainly based on acrylate, emphasizing material selection and formulation strategies that achieve efficient dispersion nanofillers (NFs). We begin by exploring various types UV-curing coatings delve deeper into their key components: monomers, oligomers, photoinitiators, fillers, additives. Different components examples are presented. Furthermore, this delves critical importance modifying NFs to tune physical properties composite. It provides an overview commonly used underscores surface modification (chemical physical) as a pivotal technique for producing high-performance PNCs. Additionally, additives such adhesion promoters, anti-foaming agents, wetting dispersing agents discussed, functions within process. blending methods also discussed. The paper concludes summarizing presenting recent advancements in offers valuable insights researchers engineers working advanced materials.

Language: Английский

Machine Learning‐Assisted High‐Throughput Screening of Nanozymes for Ulcerative Colitis DOI Creative Commons

Xianguang Zhao,

Yixin Yu, Xudong Xu

et al.

Advanced Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 12, 2025

Ulcerative colitis (UC) is a chronic gastrointestinal inflammatory disorder with rising prevalence. Due to the recurrent and difficult-to-treat nature of UC symptoms, current pharmacological treatments fail meet patients' expectations. This study presents machine learning-assisted high-throughput screening strategy expedite discovery efficient nanozymes for treatment. Therapeutic requirements, including antioxidant property, acid stability, zeta potential, are quantified predicted by using learning model. Non-quantifiable attributes, intestinal barrier repair efficacy biosafety, assessed via screening. Feature significance analysis, sure independence screening, sparsifying operator symbolic regression reveal high-dimensional structure-activity relationships between material features therapeutic needs. SrDy

Language: Английский

Citations

2

A review of chitosan-based multifunctional nanocomposites for drug/gene/protein delivery and gene therapy in cancer treatments: Promises, challenges and outlooks DOI
Ali Khorasani, Seyed Morteza Naghib

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141394 - 141394

Published: Feb. 1, 2025

Language: Английский

Citations

2

Smart biomaterial gels for periodontal therapy: A novel approach DOI Open Access

Rabia Ashfaq,

Anita Kovács, Szilvia Berkó

et al.

Biomedicine & Pharmacotherapy, Journal Year: 2025, Volume and Issue: 183, P. 117836 - 117836

Published: Jan. 19, 2025

Language: Английский

Citations

1

Carbon Dots: New Rising Stars in the Carbon Family for Diagnosis and Biomedical Applications DOI Creative Commons
Muneeb Ullah, Uzma Azeem Awan, Haider Ali

et al.

Journal of Nanotheranostics, Journal Year: 2024, Volume and Issue: 6(1), P. 1 - 1

Published: Dec. 28, 2024

Carbon dots (CDs) are a class of carbon-based nanomaterials undergoing rapid development with broad potential applications across diverse biomedical fields. These materials highly attractive for diagnostics, therapeutics, and nanomedicine due to their remarkable optical physicochemical properties, including photoluminescence, biocompatibility, aqueous dispersibility. CDs can be synthesized using various techniques, ranging from top-down bottom-up approaches. Among these, biogenic synthesis, utilizing natural sources waste materials, presents an eco-friendly sustainable alternative. have exhibited considerable promise in especially bioimaging biosensing, providing both high sensitivity precise identification. presently being investigated the pharmaceutical sector cancer infection treatment, as well photodynamic thermal therapies. The advancement CD composites, through enhanced functionality broader application, facilitates novel research nanomedicine. This article highlights advantages CDs, focusing on structural classification, versatility synthesis methods. Furthermore, safety toxicity profiles critically analyzed. In conclusion, innocuity, adaptability, multifunctionality position them cornerstone nanotechnology applications. With applicability promising potential, stand poised drive significant innovation other domains, heralding new era material development.

Language: Английский

Citations

4

Synthesis and Application of Zr MOF UiO-66 Decorated with Folic Acid-Conjugated Poly Ethylene Glycol as a Strong Nanocarrier for the Targeted Drug Delivery of Epirubicin DOI
Atieh Hashemi,

Danial Aliasgari,

Hamid Abbasi

et al.

Journal of Cluster Science, Journal Year: 2025, Volume and Issue: 36(2)

Published: Feb. 4, 2025

Language: Английский

Citations

0

Nanoengineered Copper: Revolutionizing Breast Cancer Care DOI Open Access
Sudip Mandal

International Journal of Scientific Research in Science Engineering and Technology, Journal Year: 2025, Volume and Issue: 12(1), P. 164 - 180

Published: Feb. 3, 2025

Breast cancer continues to rank as a predominant cause of illness and death among women globally, emphasizing the critical need for innovative effective treatment approaches. Traditional methods such chemotherapy, surgery, radiation therapy often face limitations, including toxicity, resistance, non-specific targeting. In recent years, advancements in nanotechnology have brought about transformative solutions, with nanoengineered copper emerging frontrunner. Nanoengineered copper’s unique properties- its catalytic capabilities, biocompatibility, potential surface modification- offer unprecedented opportunities revolutionize breast care. These nanoparticles not only enable precise targeting cells but also improve diagnostic accuracy through advanced imaging techniques. Furthermore, their application photothermal photodynamic therapies provides dual approach destroying while minimizing harm healthy tissues. With ability modulate tumor microenvironment act platform combination therapies, holds immense promise both early detection treatment. This article explores wide-ranging applications copper, from innovations therapeutic breakthroughs, underscoring redefine management patient outcomes.

Language: Английский

Citations

0

Advances in sensing technologies using functional carbon nanotube-hydrogel nanocomposites DOI
Mansour A.S. Salem,

Aadil Shafi Bhat,

Rabiya Mehandi

et al.

Inorganic Chemistry Communications, Journal Year: 2025, Volume and Issue: unknown, P. 114139 - 114139

Published: Feb. 1, 2025

Language: Английский

Citations

0

Advanced Disease Therapeutics Using Engineered Living Drug Delivery Systems DOI
Narsimha Mamidi,

Fátima Franco De Silva,

Amin Orash Mahmoud Salehi

et al.

Nanoscale, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Biological barriers significantly impede the delivery of nanotherapeutics to diseased tissues, diminishing therapeutic efficacy across pathologies such as cancer and inflammatory disorders. Although conventional strategies integrate multifunctional designs molecular components into nanomaterials (NMs), many approaches remain insufficient overcome these barriers. Key challenges, including inadequate drug accumulation at target sites nonspecific biodistribution, persist in nanotherapeutic development. NMs, which harness ability precisely modulate spatiotemporally control release kinetics, represent a transformative platform for targeted therapy. In this review, we highlight biological obstacles limiting effective treatment evaluate how stimuli-responsive NMs address constraints. By leveraging exogenous endogenous stimuli, improve specificity, reduce off-target effects, amplify activity within pathological microenvironments. We systematically analyze rational design synthesis driven by advances oncology, biomaterials science, nanoscale engineering. Furthermore, NM classes-including polymeric, lipid-based, inorganic, hybrid systems explore functionalization using targeting ligands, antibodies, biomimetic coatings. Diverse are evaluated, small-molecule prodrug activation, peptide- protein-based targeting, nucleic acid payloads, engineered cell-mediated transport. Despite promise challenges biocompatibility, scalable fabrication, clinical translation must be addressed. elucidating structure-function relationships refining stimulus-triggered mechanisms, pave way precision oncology strategies, enabling patient-specific therapies with enhanced safety. This interdisciplinary insights aims catalyze innovation next-generation nanomedicine treatment.

Language: Английский

Citations

0

Advanced 3D Materials for Corneal Stroma Regeneration: A Preclinical Progress DOI
Amin Orash Mahmoud Salehi, Maryam Soleimani, Kevin Catzim-Ríos

et al.

Journal of Materials Chemistry B, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Corneal stromal defects cause global blindness and entail unmet solutions beyond transplants. This review highlights scaffolds, biomaterials, signaling cues in corneal stroma engineering to advance next-generation vision therapies.

Language: Английский

Citations

0

Nanocomposites for Bone Tissue Engineering Application DOI
Monalisha Mallick,

Ramakrishna Prasad Are,

Anju R. Babu

et al.

Next research., Journal Year: 2025, Volume and Issue: unknown, P. 100261 - 100261

Published: March 1, 2025

Language: Английский

Citations

0