International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 248, P. 125888 - 125888
Published: July 19, 2023
Language: Английский
Applied Materials Today, Journal Year: 2022, Volume and Issue: 29, P. 101560 - 101560
Published: June 22, 2022
Language: Английский
Citations
86
Advanced Engineering Materials, Journal Year: 2023, Volume and Issue: 25(21)
Published: Aug. 29, 2023
Stimuli‐responsive polymers (SRPs) are special types of soft materials, which have been extensively used for developing flexible actuators, robots, wearable devices, sensors, self‐expanding structures, and biomedical thanks to their ability change shapes functional properties in response external stimuli including light, humidity, heat, pH, electric field, solvent, magnetic field or combinations two more these stimuli. In recent years, additive manufacturing (AM) aka 3D printing technology SRPs, also known as 4D printing, has gained phenomenal attention different engineering fields, its unique develop complex, personalized, innovative undergo twisting, elongating, swelling, rolling, shrinking, bending, spiraling, other complex morphological transformations. Herein, an effort made provide insightful information about the AM techniques, type applications including, but not limited tissue engineering, bionics, construction, smart textiles. This article incorporates current challenges prospects, hoping basis utilization this fields. It is expected that amalgamation with SRPs would unparalleled advantages arenas.
Language: Английский
Citations
84
Materials Research Express, Journal Year: 2023, Volume and Issue: 10(2), P. 024003 - 024003
Published: Feb. 1, 2023
Abstract Hydrogel is being broadly studied due to their tremendous properties, such as swelling behavior and biocompatibility. Numerous review articles have discussed hydrogel polymer types, synthesis methods, applications. can be synthesized by physical chemical cross-linking methods. One type of the method freeze-thaw (F–T), which works based on crystallization process precursor solution form a cross-link. To date, there has been no paper discusses F–T technique specifically comprehensively. Most previous that exposed usually mentioned small part method. This attempts discuss In more detail, this covers basic principles formation in an way, parameters influence formation, properties hydrogel, its application biomedical field.
Language: Английский
Citations
77
Chemical Engineering Journal, Journal Year: 2022, Volume and Issue: 451, P. 138494 - 138494
Published: Aug. 5, 2022
Language: Английский
Citations
76
Giant, Journal Year: 2023, Volume and Issue: 17, P. 100209 - 100209
Published: Nov. 15, 2023
Additive manufacturing (AM) aka three-dimensional (3D) printing has been a well-established and unparalleled technology, which is expanding the boundaries of materials science exhibiting an enormous potential to fabricate intricate geometries for healthcare, electronics, construction sectors. In contemporary era, combination AM technology stimuli-responsive hydrogels (SRHs) helps create dynamic functional structures with extreme accuracy, are capable changing their shape, functional, or mechanical properties in response environmental cues such as humidity, heat, light, pH, magnetic field, electric etc. 3D SRHs permits creation on-demand dynamically controllable shapes excellent control over various self-repair, self-assembly, multi-functionality, These accelerate researchers think unthinkable applications. Additively manufactured objects have shown applications like tissue engineering, drug delivery, soft robots, sensors, other biomedical devices. The current review provides recent progress SRHs, more focus on techniques, stimuli mechanisms, shape morphing behaviors, Finally, trends future roadmap additively smart different also presented, will be helpful research. This holds great promise providing fundamental knowledge about diverse
Language: Английский
Citations
71
Materials Horizons, Journal Year: 2023, Volume and Issue: 10(9), P. 3325 - 3350
Published: Jan. 1, 2023
This review provides a brief overview of the recent developments in hydrogel systems that respond dynamically to various stimuli, including some interesting fabrication strategies, and their application cardiac, bone, neural tissue regeneration.
Language: Английский
Citations
68
Bioactive Materials, Journal Year: 2023, Volume and Issue: 32, P. 242 - 259
Published: Oct. 12, 2023
Regulating macrophage activation precisely is crucial in treating chronic inflammation osteoarthritis (OA). However, the stable pro-inflammatory state and deep distribution of macrophages vivo pose a great challenge to treatment. In this study, inspired by innate immune, immune cell mobilized hydrogel microspheres were constructed microfluidic methods load chemokines, antibodies engineered membrane vesicles (sEVs) via covalent non-covalent junctions. The microspheres, based on mixture streptavidin grafted hyaluronic acid methacrylate (HAMA-SA) Chondroitin sulfate (ChSMA) (HCM), can recruit, capture reprogram proinflammatory joint cavity improve inflammatory microenvironment. vitro experiments demonstrated that had excellent recruitment, capture, reprogramming abilities. Pro-inflammatory be transformed into anti-inflammatory with an efficiency 88.5 %. Animal also revealed significant reduction synovial cartilage matrix degradation OA. Therefore, may effective treatment OA for future.
Language: Английский
Citations
50
Small, Journal Year: 2023, Volume and Issue: 20(9)
Published: Oct. 17, 2023
Bacteria-induced epidemics and infectious diseases are seriously threatening the health of people around world. In addition, antibiotic therapy has been inducing increasingly more serious bacterial resistance, which makes it urgent to develop new treatment strategies combat bacteria, including multidrug-resistant bacteria. Natural extracts displaying antibacterial activity good biocompatibility have attracted much attention due greater concerns about safety synthetic chemicals emerging drug resistance. These components can be isolated utilized as antimicrobials, well transformed, combined, or wrapped with other substances by using modern assistive technologies fight bacteria synergistically. This review summarizes recent advances in natural from three kinds sources-plants, animals, microorganisms-for applications. work discusses corresponding mechanisms future development fields.
Language: Английский
Citations
48
Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 13(22)
Published: May 9, 2024
Hydrogels have emerged as promising candidates for biomedical applications, especially in the field of antibacterial therapeutics, due to their unique structural properties, highly tunable physicochemical and excellent biocompatibility. The integration stimuli-responsive functions into hydrogels holds potential enhance properties therapeutic efficacy, dynamically responding different external or internal stimuli, such pH, temperature, enzymes, light. Therefore, this review describes applications hydrogel dressings responsive stimuli therapy. collaborative interaction between materials is discussed. This synergistic approach, contrast conventional materials, not only amplifies effect but also alleviates adverse side effects diminishes incidence multiple infections drug resistance. provides a comprehensive overview current challenges outlines future research directions hydrogels. It underscores imperative ongoing interdisciplinary aimed at unraveling mechanisms wound healing. understanding crucial optimizing design implementation Ultimately, aims offer scientific guidance development practical clinical application dressings.
Language: Английский
Citations
26
Materials, Journal Year: 2024, Volume and Issue: 17(2), P. 278 - 278
Published: Jan. 5, 2024
Effective wound treatment has become one of the most important challenges for healthcare as it continues to be leading causes death worldwide. Therefore, care technologies significantly evolved in order provide a holistic approach based on various designs functional dressings. Among them, hydrogels have been widely used due their biocompatibility and similarity extracellular matrix. The hydrogel formula offers control an optimal moisture level its ability absorb excess fluid from or release needed. Additionally, can successfully integrated with plethora biologically active components (e.g., nanoparticles, pharmaceuticals, natural extracts, peptides), thus enhancing performance resulting composite healing applications. In this review, the-state-of-the-art discoveries related stimuli-responsive hydrogel-based dressings summarized, taking into account antimicrobial, anti-inflammatory, antioxidant, hemostatic properties, well other effects re-epithelialization, vascularization, restoration tissue) use.
Language: Английский
Citations
22