Social jetlag and obesity: A systematic review and meta‐analysis DOI
Arman Arab, Elham Karimi, Marta Garaulet

et al.

Obesity Reviews, Journal Year: 2023, Volume and Issue: 25(3)

Published: Dec. 10, 2023

Summary Social jetlag, the weekly variation in sleep timing, is proposed to contribute increased obesity risk, potentially because of misalignment behavioral cycles relative endogenous circadian timing system. This systematic review and meta‐analysis aim determine association between social jetlag adiposity‐related measures using observational studies. We reviewed 477 references, which 43 studies met inclusion criteria with a total sample size 231,648. There was positive body mass index (correlation coefficient [ r ]: 0.12; 95%CI, 0.07, 0.17; P < 0.001; I 2 = 94.99%), fat ( : 0.10; 0.05, 0.15; 0.00%), (fat divided by height meter squared, β 0.14 kg/m ; 0.23; 56.50%), percent 0.37; 0.33, 0.41; 96.17%), waist circumference 0.06, 0.24; 90.83%), risk having overweight/obesity (odds ratio: 1.20; 1.02, 1.140; 0.039; 98.25%). positively consistently associated multiple obesity‐related anthropometric measures. Further are needed test causality, underlying mechanisms, whether interventions based on increasing regularity sleep/wake cycle can aid battle against pandemic.

Language: Английский

Autophagy in ovary and polycystic ovary syndrome: role, dispute and future perspective DOI Open Access

Sanjana Kumariya,

Vaibhave Ubba,

Rajesh Kumar Jha

et al.

Autophagy, Journal Year: 2021, Volume and Issue: 17(10), P. 2706 - 2733

Published: June 23, 2021

Polycystic ovary syndrome (PCOS) is a unification of endocrine and metabolic disorders has become immensely prevalent among women fertile age. The prime organ affected in PCOS the its distressed functioning elicits disturbed reproductive outcomes. In ovary, macroautophagy/autophagy performs pivotal role directing chain events starting from oocytes origin until fertilization. Recent discoveries demonstrate significant autophagy pathogenesis PCOS. Defective follicular cells during different stages follicles observed ovary. Exploring pathways provides platform for predicting possible cause altered ovarian physiology this review, we have emphasized autophagy’s governing development under normal circumstances PCOS, including abnormalities associated with such as anovulation, hyperandrogenemia, disturbances, related abnormality. So far, few studies linked propose essential progression. However, detailed knowledge area lacking. Here summarized latest to This review’s main objective provide background connection suggested novel proposal future aid better understanding pathogenesis.Abbreviations: AE: androgen excess; AF: antral follicle; AKT/PKB: AKT serine/threonine kinase; AMH: anti-Mullerian hormone; AMPK: AMP-activated protein ATG: autophagy-related; BCL2: BCL2 apoptosis regulator; BECN1: beclin 1; BMP: bone morphogenetic protein; CASP3: caspase 3; CL: corpus luteum; CYP17A1/P450C17: cytochrome P450 family 17 subfamily A member CYP19A1: 19 DHEA: dehydroepiandrosterone; EH: endometrial hyperplasia; FF: fluid; FOXO: forkhead box O; FSH: follicle stimulating GC: granulosa cell; GDF: growth differentiation factor; HA: hyperandrogenemia; HMGB1: high mobility group IGF1: insulin like factor INS: insulin; IR: resistance; LHCGR/LHR: luteinizing hormone/choriogonadotropin receptor; MAP1LC3B/LC3B: microtubule 1 light 3 beta; MAPK/ERK: mitogen-activated MAPK8/JNK: kinase 8; MTOR: mechanistic target rapamycin MTORC: complex; NAFLD: nonalcoholic fatty liver disease; NFKB: nuclear kappa B; OLR1/LOX-1: oxidized low density lipoprotein receptor oxLDL: low-density lipoproteins; PA: palmitic acid; PCOS: polycystic syndrome; PF: primary PGC: primordial germ PI3K: phosphoinositide 3-kinase; PMF: ROS: reactive oxygen species; RP: resting pool; SIRT1: sirtuin SQSTM1/p62: sequestosome T2DM: type 2 diabetes mellitus; TC: theca TUG1: taurine up-regulated

Language: Английский

Citations

192

Melatonin Effects on Glucose Metabolism: Time To Unlock the Controversy DOI
Marta Garaulet, Jingyi Qian, José C. Florez

et al.

Trends in Endocrinology and Metabolism, Journal Year: 2020, Volume and Issue: 31(3), P. 192 - 204

Published: Jan. 1, 2020

Language: Английский

Citations

146

Melatonin and Health: Insights of Melatonin Action, Biological Functions, and Associated Disorders DOI Open Access
Sheikh Bilal Ahmad, Aarif Ali, Midhat Bilal

et al.

Cellular and Molecular Neurobiology, Journal Year: 2023, Volume and Issue: 43(6), P. 2437 - 2458

Published: Feb. 8, 2023

Language: Английский

Citations

139

Late isocaloric eating increases hunger, decreases energy expenditure, and modifies metabolic pathways in adults with overweight and obesity DOI Creative Commons

Nina Vujović,

Matthew J. Piron,

Jingyi Qian

et al.

Cell Metabolism, Journal Year: 2022, Volume and Issue: 34(10), P. 1486 - 1498.e7

Published: Oct. 1, 2022

Language: Английский

Citations

92

Light modulates glucose metabolism by a retina-hypothalamus-brown adipose tissue axis DOI Creative Commons
Jianjun Meng, Jiawei Shen, Guang Li

et al.

Cell, Journal Year: 2023, Volume and Issue: 186(2), P. 398 - 412.e17

Published: Jan. 1, 2023

Language: Английский

Citations

58

Timing of Moderate to Vigorous Physical Activity, Mortality, Cardiovascular Disease, and Microvascular Disease in Adults With Obesity DOI Open Access
Angelo Sabag, Matthew Ahmadi, Monique E. François

et al.

Diabetes Care, Journal Year: 2024, Volume and Issue: 47(5), P. 890 - 897

Published: April 9, 2024

To assess the association between timing of aerobic moderate to vigorous physical activity (MVPA) and risk cardiovascular disease (CVD), microvascular (MVD), all-cause mortality in adults with obesity a subset type 2 diabetes (T2D).

Language: Английский

Citations

21

Chrono-nutrition for the prevention and treatment of obesity and type 2 diabetes: from mice to men DOI Open Access
John A. Hawley, Paolo Sassone–Corsi, Juleen R. Zierath

et al.

Diabetologia, Journal Year: 2020, Volume and Issue: 63(11), P. 2253 - 2259

Published: Aug. 6, 2020

Language: Английский

Citations

123

Late eating is associated with cardiometabolic risk traits, obesogenic behaviors, and impaired weight loss DOI Creative Commons
Hassan S. Dashti,

Puri Gómez-Abellán,

Jingyi Qian

et al.

American Journal of Clinical Nutrition, Journal Year: 2020, Volume and Issue: 113(1), P. 154 - 161

Published: Aug. 26, 2020

Language: Английский

Citations

110

Time-Restricted Eating as a Nutrition Strategy for Individuals with Type 2 Diabetes: A Feasibility Study DOI Open Access
Evelyn B. Parr, Brooke L. Devlin, Karen Lim

et al.

Nutrients, Journal Year: 2020, Volume and Issue: 12(11), P. 3228 - 3228

Published: Oct. 22, 2020

Individuals with type 2 diabetes (T2D) require a long-term dietary strategy for blood glucose management and may benefit from time-restricted eating (TRE, where the duration between first last energy intake is restricted to 8–10 h/day). We aimed determine feasibility of TRE individuals T2D. Participants T2D (HbA1c >6.5 <9%, window >12 h/day) were recruited pre-post, non-randomised intervention consisting 2-week Habitual period establish baseline intake, followed by 4-weeks during which they instructed limit all occasions 10:00 19:00 h on as many days each week possible. Recruitment, retention, acceptability, safety recorded throughout study indicators feasibility. Dietary glycaemic control, psychological well-being, cognitive outcomes, physiological measures explored secondary outcomes. From 594 interested persons, 27 eligible individuals, 24 participants enrolled 19 (mean ± SD; age: 50 9 years, BMI: 34 5 kg/m2, HbA1c: 7.6 1.1%) completed 6-week study. Overall daily did not change (~8400 kJ/d; 35% carbohydrate, 20% protein, 41% fat, 1% alcohol) periods (~8500 19% 42% alcohol). Compliance was 72 24% 28 (i.e., ~5 days/week), varied adherence (range: 4–100%). Comparisons adherent vs. non-adherent showed that 9-h reduced through lower absolute carbohydrate alcohol intakes. Overall, significantly improve control −0.2 0.4%; p = 0.053) or reduce body mass. impair variable effects function. described hunger, stressors, emotions main barriers adherence. demonstrate feasible achievable these adhere at least days/week. The degree strongly influenced intake. Future trials supporting incorporate in regular life overcome

Language: Английский

Citations

110

Timing of Food Intake: Identifying Contributing Factors to Design Effective Interventions DOI Creative Commons
Hassan S. Dashti, Frank A. J. L. Scheer, Richa Saxena

et al.

Advances in Nutrition, Journal Year: 2018, Volume and Issue: 10(4), P. 606 - 620

Published: Dec. 27, 2018

Language: Английский

Citations

95