The Science of The Total Environment, Journal Year: 2021, Volume and Issue: 778, P. 145196 - 145196
Published: Feb. 10, 2021
Language: Английский
Natural Product Reports, Journal Year: 2021, Volume and Issue: 38(2), P. 362 - 413
Published: Jan. 1, 2021
This review covers the literature published in 2019 for marine natural products (MNPs), with 719 citations (701 period January to December 2019) referring compounds isolated from microorganisms and phytoplankton, green, brown red algae, sponges, cnidarians, bryozoans, molluscs, tunicates, echinoderms, mangroves other intertidal plants microorganisms. The emphasis is on new (1490 440 papers 2019), together relevant biological activities, source organisms country of origin. Pertinent reviews, biosynthetic studies, first syntheses, syntheses that led revision structures or stereochemistries, have been included. Methods used study fungi their chemical diversity also discussed.
Language: Английский
Citations
296
The Innovation, Journal Year: 2021, Volume and Issue: 2(2), P. 100092 - 100092
Published: Feb. 11, 2021
The recent mass mortality event of more than 330 African elephants in Botswana has been attributed to biotoxins produced by cyanobacteria; however, scientific evidence for this is lacking. Here, synthesizing multiple sources data, we show that, during the past decades, widespread hypertrophic waters Southern Africa have entailed an extremely high risk and frequent exposure cyanotoxins wildlife within area, which functions as a hotspot mammal species richness. hot dry climatic extremes most likely acted primary trigger perhaps also prehistoric events. As such climate are projected become near future, there that similar tragedies may take place, rendering megafauna species, especially those already endangered, extinction. Moreover, cyanotoxin poisoning amplified change unexpected cascading effects on human societies. Seen perspective, tragic death world's largest terrestrial serves alarming early warning signal future environmental catastrophes Africa. We suggest systematic, quantitative assessments made precautionary actions mitigate risks taken without hesitation ensure health sustainability societies region.
Language: Английский
Citations
149
Water Air & Soil Pollution, Journal Year: 2024, Volume and Issue: 235(1)
Published: Jan. 1, 2024
Abstract Cyanobacteria harmful algal blooms (cHABs) are increasingly becoming an emerging threat to aquatic life, ecotourism, and certain real estate investments. Their spontaneous yet sporadic occurrence has made mitigation measures a cumbersome task; moreover, current trends regarding anthropogenic activities, especially in agriculture industry portend further undesirable events. Apart from the aesthetic degeneration they create their respective habitats, equally capable of secreting toxins, which altogether present grave environmental medical consequences. In this paper, we gave update on factors that influence cHABs, cyanotoxin exposure routes, public health implications, impacts fish, pets, livestock. We discussed social economic impacts, risk assessment, management problems for cHABs and, thereafter, assessed extant approaches including prevention, control, proliferation cyanobacterial blooms. light this, suggest more intensified research should be directed standardization procedures analysis. Also, provision standardized reference material quantification cyanotoxins is vital routine monitoring as well development strong situ sensors quantifying detecting HABs cells toxins waterbodies prevent adverse cHABs. investigations into natural environmentally friendly approach cyanobacteria necessary appropriate deployment artificial intelligence required. Finally, wish redirect focus authorities protecting drinking water supply sources, products, food sources contamination implement proper treatment protect citizens potential threat.
Language: Английский
Citations
50
The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 917, P. 170078 - 170078
Published: Jan. 17, 2024
Cyanobacteria are highly prevalent blue-green algae that grow in stagnant and nutrient-rich water bodies. Environmental conditions, such as eutrophication human activities, increased the cyanobacterial blooms freshwater resources worldwide. The excessive bloom formation has also resulted an alarming surge of toxins. Prolonged exposure to cyanotoxins is a potential threat natural ecosystems, animal health by spoilage quality bathing drinking water. Various molecular analytical methods have been proposed monitor their occurrence understand global distribution. Moreover, different physical, chemical, biological approaches employed control toxins mitigate occurrence. Numerous strategies engaged treatment plants (DWTPs). However, degree varies greatly primarily determined source, properties, operating parameters temperature, pH, cyanotoxin variants levels. A comprehensive compilation methods, from traditional more advanced oxidation processes (AOPs), presented for removal intracellular extracellular cyanotoxins. This review discusses effectiveness various physicochemical operations limitations DWTP, These span simple levels with varying degrees differing costs implementation. Furthermore, mitigation measures applied other toxin systems considered alternative strategies.
Language: Английский
Citations
21
Toxins, Journal Year: 2020, Volume and Issue: 12(4), P. 268 - 268
Published: April 21, 2020
Microcystins (MCs) classified as hepatotoxic and carcinogenic are the most commonly reported cyanobacterial toxins found in environment. Microcystis sp. possessing a series of MC synthesis genes (mcyA-mcyJ) well documented for their excessive abundance, numerous bloom occurrences producing capacity. About 246 variants which exert severe animal human health hazards through inhibition protein phosphatases (PP1 PP2A) have been characterized. To minimize prevent consequences, World Health Organization proposed 1 µg/L guidelines safe drinking water quality. Further utilization bacteria that represent promising biological treatment approach to degrade remove from bodies without harming environment has gained global attention. Thus present review described toxic effects bacterial degradation MCs.
Language: Английский
Citations
127
The Science of The Total Environment, Journal Year: 2020, Volume and Issue: 764, P. 142319 - 142319
Published: Sept. 13, 2020
Language: Английский
Citations
124
Environmental Research, Journal Year: 2020, Volume and Issue: 192, P. 110254 - 110254
Published: Sept. 28, 2020
Language: Английский
Citations
120
Toxins, Journal Year: 2020, Volume and Issue: 12(10), P. 641 - 641
Published: Oct. 4, 2020
Cyanobacterial harmful algal blooms (CyanoHABs) produce microcystins (MCs) which are associated with animal and human hepatotoxicity. Over 270 variants of MC exist. MCs have been continually studied due their toxic consequences. Monitoring water quality to assess the presence is utmost importance although it often difficult because CyanoHABs may generate multiple variants, low concentration in water. To effectively manage control these toxins prevent health risks, sensitive, fast, reliable methods capable detecting required. This paper aims review three main analytical used detect ranging from biological (mouse bioassay), biochemical (protein phosphatase inhibition assay enzyme linked immunosorbent assay), chemical (high performance liquid chromatography, chromatography-mass spectrometry, high capillary electrophoresis, gas chromatography), as well newly emerging biosensor methods. In addition, current state regarding novel development usage, merits limitations presented. Finally, this also provides recommendations future research directions towards method application improvement.
Language: Английский
Citations
101
Harmful Algae, Journal Year: 2020, Volume and Issue: 96, P. 101829 - 101829
Published: May 27, 2020
Language: Английский
Citations
76
Toxins, Journal Year: 2020, Volume and Issue: 12(10), P. 629 - 629
Published: Oct. 1, 2020
Toxin-producing cyanobacteria in aquatic, terrestrial, and aerial environments can occur alongside a wide range of additional health hazards including biological agents synthetic materials. Cases intoxications involving cyanotoxins, with exposure to hazards, are discussed. Examples the co-occurrence such combinations reviewed, cyanotoxins plus algal toxins, microbial pathogens fecal indicator bacteria, metals, pesticides, microplastics. Toxicity assessments cyanobacteria, these agents, where investigated bioassays defined combinations, discussed further research needs identified.
Language: Английский
Citations
74