Microbial Biotechnology,
Journal Year:
2016,
Volume and Issue:
9(3), P. 330 - 354
Published: Feb. 16, 2016
Summary
There
is
a
pressing
need
to
understand
and
optimize
biological
control
so
as
avoid
over‐reliance
on
the
synthetic
chemical
pesticides
that
can
damage
environmental
human
health.
This
study
focused
interactions
between
novel
biocontrol‐strain,
Bacillus
sp.
JC12GB43,
potato‐pathogenic
Phytophthora
Fusarium
species.
In
assays
carried
out
in
vitro
potato
tuber,
bacterium
was
capable
of
near‐complete
inhibition
pathogens.
sufficiently
xerotolerant
(water
activity
limit
for
growth
=
0.928)
out‐perform
infestans
(~0.960)
challenge
coeruleum
(~0.847)
sambucinum
(~0.860)
towards
lower
limits
their
windows.
Under
some
conditions,
however,
strain
JC12GB43
stimulated
proliferation
pathogens:
instance,
growth‐rate
increased
under
chaotropic
conditions
(132
mM
urea)
by
>100%
tubers
(2‐M
glycerol)
up
570%.
Culture‐based
involving
macromolecule‐stabilizing
(kosmotropic)
compatible
solutes
provided
proof‐of‐principle
may
provide
kosmotropic
metabolites
plant
pathogen
destabilize
macromolecular
systems
fungal
cell.
Whilst
unprecedented,
this
finding
consistent
with
earlier
reports
fungi
utilize
derived
from
bacterial
cells.
Unless
antimicrobial
activities
candidate
biocontrol
strains
are
assayed
over
full
range
field‐relevant
parameters,
agents
promote
infections
thereby
reduce
crop
yields.
These
findings
indicate
activity,
therefore,
ought
be
regarded
mode‐of‐behaviour
(dependent
prevailing
conditions)
rather
than
an
inherent
property
strain.
Microbial Biotechnology,
Journal Year:
2016,
Volume and Issue:
10(2), P. 296 - 322
Published: June 7, 2016
Fungi
of
the
genus
Aspergillus
are
widespread
in
environment.
Some
species,
most
commonly
fumigatus,
may
lead
to
a
variety
allergic
reactions
and
life-threatening
systemic
infections
humans.
Invasive
aspergillosis
occurs
primarily
patients
with
severe
immunodeficiency,
has
dramatically
increased
recent
years.
There
several
factors
at
play
that
contribute
aspergillosis,
including
both
fungus
host-related
such
as
strain
virulence
host
pulmonary
structure/immune
status,
respectively.
The
environmental
tenacity
Aspergilllus,
its
dominance
diverse
microbial
communities/habitats,
ability
navigate
ecophysiological
biophysical
challenges
infection
attributable,
large
part,
robust
stress-tolerance
biology
exceptional
capacity
generate
cell-available
energy.
Aspects
stress
metabolism,
ecology,
interactions
animal
hosts,
clinical
presentations
treatment
regimens
have
been
well-studied
over
past
Here,
we
synthesize
these
findings
relation
way
which
some
species
become
successful
opportunistic
pathogens
human-
other
hosts.
We
focus
on
capabilities
pathogens,
key
aspects
their
ecophysiology
flexibility
undergo
sexual
cycle
or
form
cryptic
species.
Additionally,
advances
diagnosis
disease
discussed
well
implications
questions
yet
be
resolved.
Frontiers in Microbiology,
Journal Year:
2021,
Volume and Issue:
12
Published: Aug. 26, 2021
The
long-term
and
excessive
usage
of
pesticides
is
an
enormous
burden
on
the
environment,
which
also
increases
pest
resistance.
To
overcome
this
problem,
research
application
entomopathogenic
fungi,
are
both
environmentally
friendly
cause
lower
resistance,
have
gained
great
momentum.
Entomopathogenic
fungi
a
wide
range
prospects.
Apart
from
Bacillus
thuringiensis,
Beauveria
bassiana
most
studied
biopesticide.
After
invading
insect
hosts,
B.
produces
variety
toxins,
secondary
metabolites
such
as
beauvericin,
bassianin,
bassianolide,
beauverolides,
tenellin,
oosporein,
oxalic
acid.
These
toxins
help
to
parasitize
kill
hosts.
This
review
unequivocally
considers
beauveria
highly
promising
summarizes
their
attack
mechanism(s)
host
immune
system.
Genetic
engineering
strategies
improve
toxin
principles,
genes,
or
virulent
molecules
been
discussed.
Lastly,
we
discuss
future
perspective
research,
including
newly
discovered
toxins.
Fungal Diversity,
Journal Year:
2024,
Volume and Issue:
125(1), P. 1 - 71
Published: March 20, 2024
Abstract
The
field
of
mycology
has
grown
from
an
underappreciated
subset
botany,
to
a
valuable,
modern
scientific
discipline.
As
this
study
grown,
there
have
been
significant
contributions
science,
technology,
and
industry,
highlighting
the
value
fungi
in
era.
This
paper
looks
at
current
research,
along
with
existing
limitations,
suggests
future
areas
where
scientists
can
focus
their
efforts,
mycology.
We
show
how
become
important
emerging
diseases
medical
discuss
trends
potential
drug
novel
compound
discovery.
explore
phylogenomics,
its
potential,
outcomes
address
question
phylogenomics
be
applied
fungal
ecology.
In
addition,
functional
genomics
studies
are
discussed
importance
unravelling
intricate
mechanisms
underlying
behaviour,
interactions,
adaptations,
paving
way
for
comprehensive
understanding
biology.
look
research
building
materials,
they
used
as
carbon
sinks,
biocircular
economies.
numbers
always
great
interest
often
written
about
estimates
varied
greatly.
Thus,
we
needs
order
obtain
more
reliable
estimates.
aspects
machine
learning
(AI)
it
mycological
research.
Plant
pathogens
affecting
food
production
systems
on
global
scale,
such,
needed
area,
particularly
disease
detection.
latest
data
High
Throughput
Sequencing
if
still
gaining
new
knowledge
same
rate
before.
A
review
nanotechnology
is
provided
addressed.
Arbuscular
Mycorrhizal
Fungi
addressed
acknowledged.
Fungal
databases
becoming
important,
therefore
provide
major
databases.
Edible
medicinal
huge
medicines,
especially
Asia
prospects
discussed.
Lifestyle
changes
(e.g.,
endophytes,
pathogens,
and/or
saprobes)
also
extremely
trend
special
issue
Diversity.
Environmental Microbiology,
Journal Year:
2016,
Volume and Issue:
19(2), P. 687 - 697
Published: Nov. 21, 2016
Water
availability
acts
as
the
most
stringent
constraint
for
life
on
Earth.
Thus,
understanding
water
relations
of
microbial
extremophiles
is
imperative
to
our
ability
increase
agricultural
productivity
(e.g.,
by
enhancing
processing
and
turnover
dead
organic
matter
in
soils
arid
regions),
reduce
human
exposure
mycotoxins
buildings
food-supply
chain,
prevent
spoilage
foods/animal
feeds,
books,
museum
specimens
artworks
better
control
microbiology
industrial
fermentations.
Only
a
small
number
systems
can
retain
activity
at
<0.710
(ISME
J
2015
9:
1333-1351).
It
has
long-been
considered
that
resilient
these
Xeromyces
bisporus,
which
inhabits
sugar-rich
substrates
(Appl
Environ
Microbiol
1968
16:
1853-1858).
The
current
study
focused
germination
Aspergillus
penicillioides,
xerophile
also
able
grow
under
low
humidity
saline
conditions.
Investigations
differed
from
those
reported
earlier:
firstly,
aerially
borne
conidia
were
harvested,
then
used
inoculations,
their
dry
condition;
secondly,
cultures
incubated
24°C,
i.e.
below
optimum
temperature,
minimize
possibility
loss
substrate;
thirdly,
remained
sealed
throughout
73-day
period
(microscopic
examination
was
carried
out
directly
48
through
Petri
plate
lid);
fourthly,
parameters
determined
were:
rates
extent
conidial
swelling,
production
differentiated
germination-structures
septate
germlings,
subsequent
development
mycelium
and/or
sporulation;
fifthly,
assessments
over
range
water-activity
values
time
points
obtain
complete
profile
process.
Conidia
swelled,
formed
produced
germlings
just
0.585
(≡58.5%
relative
humidity),
outside
currently
understood
thermodynamic
window
life.
Furthermore,
analyses
data
suggest
theoretical
minimum
0.565
A.
penicilliodes.
In
relation
astrobiology,
findings
have
an
application
limits
extraterrestrial
environments.
light
plans
exploration
missions
Mars
other
places,
need
safeguard
martian
scientific
sites
potential
resources
(including
water)
future
habitation,
knowledge-based
effective
policy
planetary
protection
essential.
As
it
is,
Mars-bound
spacecraft
may
frequently
be
contaminated
with
aspergilli
penicillioides)
organisms
which,
when
transported
bodies,
pose
contamination
risk.
crafting
countermeasures
offset
this,
important
know
precisely
possible
capabilities
interplanetary
visitors.