Antimicrobial Activity of Probiotic Bacteria Isolated from Plants: A Review

Foods, Journal Year: 2025, Volume and Issue: 14(3), P. 495 - 495

Published: Feb. 4, 2025

Lactic acid bacteria (LAB) constitute a heterogeneous group of isolated from fermented foods, animals, plants, and mammalian guts, with many health-promoting properties. Probiotics antagonistic properties against human pathogens foodborne have garnered significant attention the scientific fraternity. A dedicated review focusing on plant-derived probiotic their has not been comprehensively reviewed. Thus, this aimed at providing an overview LAB isolates derived several unconventional sources such as fruits, seeds, fruit pulp, leaves, roots, vegetables, grasses, flowers antibacterial, antifungal, antiviral This paper reviewed antimicrobial different genera, Lactobacillus, Leuconostoc, Weissella, Enterococcus, Pediococcus, Bacillus, Fructobacillus, postbiotics, paraprobiotics. Several important mechanisms, including secretion bacteriocins, bacteriocin-like substances, reuterin, organic acids (lactic acetic), peptides, exopolysaccharides, hydrogen peroxide, attributed to actions pathogens. However, precise mode action is poorly understood; hence, further research should be conducted reveal detailed mechanisms. Finally, discusses summary future implications. Given significance, compounds can potentially exploited in food preservation safety or for medicinal applications after evaluating safety.

Language: Английский

---

Probiotics and Paraprobiotics: Effects on Microbiota-Gut-Brain Axis and Their Consequent Potential in Neuropsychiatric Therapy

Probiotics and Antimicrobial Proteins, Journal Year: 2024, Volume and Issue: 16(4), P. 1440 - 1464

Published: Jan. 31, 2024

Abstract Neuropsychiatric disorders are clinical conditions that affect cognitive function and emotional stability, often resulting from damage or disease in the central nervous system (CNS). These a worldwide concern, impacting approximately 12.5% of global population. The gut microbiota has been linked to neurological development function, implicating its involvement neuropsychiatric conditions. Due their interaction with microbial communities, probiotics offer natural alternative traditional treatments such as therapeutic drugs interventions for alleviating symptoms. Introduced by Metchnikoff early 1900s, live microorganisms provide various health benefits, including improved digestion, enhanced sleep quality, reduced mental problems. However, concerns about safety, particularly immunocompromised patients, warrant further investigation; this led concept “paraprobiotics”, inactivated forms beneficial safer alternative. This review begins exploring different methods inactivation, each targeting specific cellular components like DNA proteins. choice inactivation method is crucial, benefits may vary depending on employed inactivation. subsequent sections focus potential mechanisms action applications paraprobiotics therapy. Probiotics interact microbes, modulating composition dysbiosis. primarily stem gut-brain axis, bidirectional communication channel involving pathways discussed review. While research needed, promising agents management disorders.

Language: Английский

---

Bacteriocins or microbial peptides produced by probiotics

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 241 - 263

Published: Jan. 1, 2025

Language: Английский

---

Heat-killed Lactiplantibacillus plantarum WB3813 and Lactiplantibacillus plantarum WB3814 Alleviate LPS-Induced Inflammatory Damage and Apoptosis in A549 Cells

Probiotics and Antimicrobial Proteins, Journal Year: 2025, Volume and Issue: unknown

Published: March 3, 2025

Language: Английский

---

From nature to nutrition: exploring the synergistic benefits of functional foods and herbal medicines for holistic health

Applied Biological Chemistry, Journal Year: 2025, Volume and Issue: 68(1)

Published: April 21, 2025

Language: Английский

---

Heat-Killed Lactilactobacillus sakei WB2305 and Lactiplantibacillus plantarum WB2324 Inhibited LPS-Induced Inflammation in Human Airway Epithelial Cells

Probiotics and Antimicrobial Proteins, Journal Year: 2024, Volume and Issue: unknown

Published: April 9, 2024

Language: Английский

---

Immunomodulatory effects of Lactiplantibacillus plantarum CCFM8661 + stachyose on cyclophosphamide-induced immunosuppression mice

Frontiers in Immunology, Journal Year: 2025, Volume and Issue: 16

Published: Jan. 27, 2025

Introduction The increasing stress of modern life has led to a decline in immunity, sparking widespread interest new strategies boost immune function. Lactiplantibacillus plantarum and stachyose have gained attention for their immune-regulating effects, but the mechanisms combined application remain unclear. This study aims investigate immunoregulatory effects CCFM8661 with cyclophosphamide-induced immunocompromised mice. Methods Mice were divided into normal control group, model group (normal saline), positive drug (levamisole hydrochloride, 10 mg/kg), low, medium, high-dose groups (1.5×10 5 , 1.5×10 6 7 CFU + 1.5 mg stachyose). Each treatment received continuous oral gavage administration 28 days. On days 23 24, except all other intraperitoneally injected cyclophosphamide (40 mg/kg) establish an immunosuppressed model. day 28, 30 minutes after final administration, mice euthanized collect thymus, spleen, serum, ileum, feces subsequent analysis indicators, intestinal barrier function, serum cytokines, microbiota. Results combination significantly improved organ atrophy, restored morphology, normalized cytokine levels mice, indicating enhanced Additionally, it microbiota diversity by abundance Muribaculaceae while reducing Lachnospiraceae potentially promoting homeostasis. Discussion immune-enhancing achieved regulating inflammation maintaining

Language: Английский

---

Gut Microbes: Therapeutic Target for Neuropsychiatric Disorders

Journal of Psychiatric Research, Journal Year: 2025, Volume and Issue: 184, P. 27 - 38

Published: Feb. 21, 2025

Language: Английский

---

Probiotic Lactiplantibacillus plantarum Lb41 alleviates high-fat diet-induced nonalcoholic fatty liver disease in mice

Nutrition, Journal Year: 2025, Volume and Issue: unknown, P. 112735 - 112735

Published: Feb. 1, 2025

Language: Английский

---

Antibacterial, Antioxidant, and Anti-inflammatory Activities of Lacticaseibacillus paracasei Lysates Isolated from Fermented Palm Sap

Probiotics and Antimicrobial Proteins, Journal Year: 2025, Volume and Issue: unknown

Published: March 22, 2025

Paraprobiotics are inactivated microbial cells or cell fractions that confer health benefits to the consumer, and possess ability regulate both adaptive innate immune systems. They exhibit anti-inflammatory, antiproliferative, antioxidant properties, antimicrobial activities. The aim of this study is evaluate these activities Lacticaseibacillus paracasei lysates isolated from fermented palm sap. bacterial were prepared via sonication, their antibacterial activity was assessed against three pathogens using agar well diffusion assay. Antioxidant evaluated DPPH ABTS radical scavenging assays. Cytotoxicity anti-inflammatory determined in LPS-stimulated RAW 264.7 by measuring nitric oxide production, secretion, mRNA level cytokines (IL-1β, IL-6, IL-10). Among lysates, L. T1901 demonstrated strongest Escherichia coli, Bacillus cereus, Acinetobacter baumannii. Most exhibited potent activity, especially T0601 showed highest In cells, effectively reduced levels suppressed production pro-inflammatory (IL-1β IL-6); simultaneously, enhanced immunosuppressive cytokine IL-10 secretion. Furthermore, no cytotoxic effect observed lysate-treated cells. highlights potential as multifunctional agents with antibacterial, antioxidant, properties. These findings support application developing functional foods therapeutic for managing oxidative stress inflammatory diseases.

Language: Английский

---