Journal of Applied Physics,
Journal Year:
2025,
Volume and Issue:
137(5)
Published: Feb. 6, 2025
Superparamagnetic
nanoparticles
(SMNPs)
with
nonlinear
magnetic
behavior
under
alternating
fields
hold
great
potential
in
biomedical
applications,
including
hyperthermia,
biosensing,
separation,
particle
imaging,
etc.
Magnetic
hyperthermia
therapy,
based
on
the
relaxation
movement
of
SMNPs
subjected
to
an
field,
is
a
promising
modality
for
tumor
treatment.
Herein,
we
applied
stochastic
Langevin
equation
study
performance
by
taking
coupled
Brownian–Néel
rotations
into
account.
The
specific
absorption
rate
(SAR)
fluids
used
as
parameter
optimizing
amplitude
and
frequency
guiding
design
SMNPs.
Specifically,
accounting
dipole–dipole
interactions
between
SMNPs,
it
revealed
that
these
significantly
suppress
particles,
thereby
reducing
SAR.
Furthermore,
this
systematically
examines
effects
key
factors
such
concentration,
size,
anisotropy
constant
accurate
prediction
rotational
dynamics
oscillating
field
provides
valuable
theoretical
insights
technical
support
optimized
external
systems
precise
fabrication
Chemical Society Reviews,
Journal Year:
2021,
Volume and Issue:
50(20), P. 11614 - 11667
Published: Jan. 1, 2021
Magnetic
hyperthermia
(MHT)
is
a
therapeutic
modality
for
the
treatment
of
solid
tumors
that
has
now
accumulated
more
than
30
years
experience.
In
ongoing
MHT
clinical
trials
brain
and
prostate
tumors,
iron
oxide
nanoparticles
are
employed
as
intra-tumoral
agents
under
patient-safe
100
kHz
alternating
magnetic
field
(AMF)
applicator.
Although
currently
approved
by
FDA
imaging
purposes
anemia,
(MNPs)
designed
efficient
must
respond
to
specific
physical-chemical
properties
in
terms
magneto-energy
conversion,
heat
dose
production,
surface
chemistry
aggregation
state.
Accordingly,
past
few
decades,
these
requirements
have
boosted
development
new
generation
MNPs
specifically
aimed
MHT.
this
review,
we
present
an
overview
on
their
assemblies
produced
via
different
synthetic
routes,
focusing
which
MNP
features
allowed
unprecedented
heating
efficiency
levels
be
achieved
highlighting
nanoplatforms
prevent
loss
intracellular
environment.
Moreover,
review
advances
MNP-based
embrace
concept
multimodal
therapy,
aims
combine
with
chemotherapy,
radiotherapy,
immunotherapy,
photodynamic
or
phototherapy.
Next,
better
control
temperature
at
tumor,
focus
studies
optimized
maintain
gold-standard
performance
also
tackling
aim
quantitatively
assess
amount
tumor
site
regulate
conditions.
To
conclude,
future
perspectives
guidance
how
advance
therapy
will
provided.
Materials,
Journal Year:
2022,
Volume and Issue:
15(7), P. 2601 - 2601
Published: April 1, 2022
Magnetite
nanoparticles
with
different
surface
coverages
are
of
great
interest
for
many
applications
due
to
their
intrinsic
magnetic
properties,
nanometer
size,
and
definite
morphology.
widely
used
medical-biological
while
usage
in
optics
is
not
as
widespread.
In
recent
years,
nanomagnetite
suspensions,
so-called
ferrofluids,
applied
magneto-optical
properties.
This
review
gives
an
overview
synthesis
its
addition,
the
preparation
application
nanofluids
optics,
nanophotonics,
imaging
described.
Chemistry,
Journal Year:
2022,
Volume and Issue:
4(3), P. 872 - 930
Published: Aug. 27, 2022
Magnetic
nanoparticles
(MNPs)
have
evolved
tremendously
during
recent
years,
in
part
due
to
the
rapid
expansion
of
nanotechnology
and
their
active
magnetic
core
with
a
high
surface-to-volume
ratio,
while
surface
functionalization
opened
door
plethora
drug,
gene
bioactive
molecule
immobilization.
Taming
reactivity
was
achieved
by
various
techniques,
producing
MNPs
tailored
for
diagnosis
treatment
cardiovascular
or
neurological
disease,
tumors
cancer.
Superparamagnetic
iron
oxide
(SPIONs)
are
established
at
drug-delivery
systems
could
act
as
efficient
agents
MFH
(magnetic
fluid
hyperthermia).
Depending
on
intrinsic
morphological
features,
now
cover
broad
scope
which
current
review
aims
overview.
Considering
exponential
field,
will
be
limited
roughly
past
three
years.
International Journal of Molecular Sciences,
Journal Year:
2022,
Volume and Issue:
23(3), P. 1339 - 1339
Published: Jan. 25, 2022
Humans
are
exposed
to
a
complex
mix
of
man-made
electric
and
magnetic
fields
(MFs)
at
many
different
frequencies,
home
work.
Epidemiological
studies
indicate
that
there
is
positive
relationship
between
residential/domestic
occupational
exposure
extremely
low
frequency
electromagnetic
some
types
cancer,
although
other
no
relationship.
In
this
review,
after
an
introduction
on
the
MF
definition
description
natural/anthropogenic
sources,
epidemiology
MFs
cancer
reviewed,
with
reference
leukemia,
brain,
breast
cancer.
The
in
vivo
vitro
effects
reviewed
considering
both
human
animal
cells,
particular
involvement
reactive
oxygen
species
(ROS).
application
diagnostic
therapy
(theranostic)
also
by
describing
use
resonance
imaging
(MRI)
applications
for
detection
several
cancers.
Finally,
nanoparticles
described
terms
treatment
nanomedical
precise
delivery
anticancer
drugs,
nanosurgery
magnetomechanic
methods,
selective
killing
cells
hyperthermia.
supplementary
tables
provide
quantitative
data
methodologies
epidemiological
cell
biology
studies.
Although
scientists
do
not
generally
agree
cause-effect
might
be
direct
cause
but
may
contribute
produce
ROS
generate
oxidative
stress,
which
could
trigger
or
enhance
expression
oncogenes.
Pharmaceutics,
Journal Year:
2022,
Volume and Issue:
14(11), P. 2388 - 2388
Published: Nov. 5, 2022
Cancer
immunotherapy
has
tremendous
promise,
but
it
yet
to
be
clinically
applied
in
a
wider
variety
of
tumor
situations.
Many
therapeutic
combinations
are
envisaged
improve
their
effectiveness.
In
this
way,
strategies
capable
inducing
immunogenic
cell
death
(e.g.,
doxorubicin,
radiotherapy,
hyperthermia)
and
the
reprogramming
immunosuppressive
microenvironment
(TME)
M2-to-M1-like
macrophages
repolarization
tumor-associated
(TAMs))
particularly
appealing
enhance
efficacy
approved
immunotherapies
immune
checkpoint
inhibitors,
ICIs).
Due
modular
construction
versatility,
iron
oxide-based
nanomedicines
such
as
superparamagnetic
oxide
nanoparticles
(SPIONs)
can
combine
these
different
approaches
single
agent.
SPIONs
have
already
shown
safety
biocompatibility
possess
both
drug-delivery
chemotherapy,
ICIs)
magnetic
capabilities
hyperthermia
(MHT),
resonance
imaging).
review,
we
will
discuss
multiple
applications
cancer
immunotherapy,
focusing
on
theranostic
properties
target
TAMs
generate
MHT.
The
first
section
review
briefly
describe
targets
for
NPs.
following
sections
deal
with
overall
(including
MHT).
last
is
dedicated
SPION-induced
response
through
its
effects
Advanced Healthcare Materials,
Journal Year:
2024,
Volume and Issue:
13(22)
Published: April 29, 2024
Catalytic
nanoparticles
(CNPs)
as
heterogeneous
catalyst
reveals
superior
activity
due
to
their
physio-chemical
features,
such
high
surface-to-volume
ratio
and
unique
optical,
electric,
magnetic
properties.
The
CNPs,
based
on
nature,
can
either
increase
the
reactive
oxygen
species
(ROS)
level
for
tumor
antibacterial
therapy
or
eliminate
ROS
cytoprotection,
anti-inflammation,
anti-aging.
In
addition,
catalytic
of
nanozymes
specifically
trigger
a
specific
reaction
accompanied
by
optical
feature
change,
presenting
feasibility
biosensor
bioimaging
applications.
Undoubtedly,
CNPs
play
pivotal
role
in
pushing
evolution
technologies
medical
clinical
fields,
advanced
strategies
nanomaterials
rely
input
chemical
experts
develop.
Herein,
systematic
comprehensive
review
challenges
recent
development
biomedical
applications
is
presented
from
viewpoint
nanomaterial
with
additional
functions.
Furthermore,
biosafety
issue
applying
biodegradable
non-biodegradable
future
perspectives
are
critically
discussed
guide
promising
direction
developing
span-new
more
intelligent
overcoming
current
limitations.
