Microplastics and Nano-plastics Contamination in Foods: Current Understanding of the Health Impact on Human and Potential Solutions DOI Open Access
Opeyemi Deji-Oloruntoba,

Taiwo Samuel Agidigbi,

Miran Jang

et al.

European Journal of Nutrition & Food Safety, Journal Year: 2024, Volume and Issue: 16(5), P. 11 - 31

Published: April 22, 2024

Plastics released into the environment can be degraded by physical erosion, biodegradation, photocatalytic activity, and oxidation, resulting in smaller plastics particles. Microplastics (MPs) are plastic particles relatively than 5 mm size. Furthermore, microplastics with particle sizes less 1000 or 100 nm known as nano-plastics (NPs). The presence effect of MPs NPs human body has not been adequately studies, thus we aim to explain origins adept, carefully explore pathways which enter system highlight impact on health. Major examples include Polyethylene (PE), polypropylene (PP), polyvinyl chloride (PVC), polyamide (PA), polystyrene (PS), polyethylene terephthalate (PET), Acrylonitrile-Butadiene-Styrene (ABS), polymethyl methacrylate (PMMA). were found have two sources (primary secondary). primary materials purposely produced suit household industrial uses, such exfoliants for skin care products, construction, packaging materials. Secondary originated from decomposition/degradation large products over time. plants (fruits vegetables), animals (fish, crab, shrimp, oysters, mussels), water (taps, sachet, bottled water), salt, sugar, honey. Plastics' ecosystem is getting increasingly severe, it imperative that proper attention paid this issue. vast number available influence lives populace each geographic area. In review article, identified three routes through gain entrance body: oral ingestion, cutaneous (skin contact), inhalation. investigated summarized impacts most impacted organs included lungs, blood, kidney, brain, ovary, testes, intestines. review, offered a viable solution includes use biodegradable polymers, increased usage eco-friendly biotechnology engineering solutions, implementation regulatory measures. future, intend investigate bioaccumulation MPs/NPs

Language: Английский

Microplastics and Oxidative Stress—Current Problems and Prospects DOI Creative Commons
Kornelia Kadac-Czapska, Justyna Ośko, Eliza Knez

et al.

Antioxidants, Journal Year: 2024, Volume and Issue: 13(5), P. 579 - 579

Published: May 8, 2024

Microplastics (MPs) are plastic particles between 0.1 and 5000 µm in size that have attracted considerable attention from the scientific community general public, as they threaten environment. contribute to various harmful effects, including lipid peroxidation, DNA damage, activation of mitogen-activated protein kinase pathways, cell membrane breakages, mitochondrial dysfunction, lysosomal defects, inflammation, apoptosis. They affect cells, tissues, organs, overall health, potentially contributing conditions like cancer cardiovascular disease. pose a significant danger due their widespread occurrence food. In recent years, information has emerged indicating MPs can cause oxidative stress (OS), known factor accelerating aging organisms. This comprehensive evaluation exposed notable variability reported connection OS. work aims provide critical review whether harmfulness constitute environmental contaminants may result OS through analysis research existing literature, well an assessment characteristics causing Additionally, article covers analytical methodology used this field. The conclusions point necessity for further into effects on

Language: Английский

Citations

56
The alarming link between environmental microplastics and health hazards with special emphasis on cancer DOI

Sohini Goswami,

Satadal Adhikary, Suchandra Bhattacharya

et al.

Life Sciences, Journal Year: 2024, Volume and Issue: 355, P. 122937 - 122937

Published: Aug. 3, 2024

Language: Английский

Citations

24
Comparing the effects and mechanisms of exposure to polystyrene nanoplastics with different functional groups on the male reproductive system DOI
Xiao Gao, Ke Xu, Wanting Du

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 922, P. 171299 - 171299

Published: Feb. 27, 2024

Language: Английский

Citations

18
The histopathological and functional consequences of microplastic exposure DOI Creative Commons

Yujeong Lee,

Min Kyung Sung, Soo‐Eun Sung

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: 7(1)

Published: Jan. 11, 2025

As the production, usage, and disposal of plastics increase, microplastics generated—plastic particles smaller than 5 mm—increases, exacerbating environmental pollution. In turn, various organisms become increasingly exposed to contaminated environments, potentially affecting humans through food chain. Crucial findings from in vivo experiments indicate histopathological changes caused by impact morphology physiological function organisms. This study describes induced across circulatory, nervous, digestive, respiratory, reproductive systems explains associated functional alterations. Except nervous system, main morphological involve degenerative throughout body, such as apoptosis, inflammation, fibrosis. Most were inflammatory responses microplastics, leading fibrosis subsequent impairments. Various studies confirm that stimulate cells, increased reactive oxygen species cell death. Consequently, these impair related systemic functions. review highlights fundamental organs cells due discusses limitations involving showing no changes.

Language: Английский

Citations

2
Detrimental consequences of micropolymers associated plasticizers on endocrinal disruption DOI Creative Commons

Utsa Saha,

Puja Kumari,

Aishee Ghosh

et al.

Materials Today Bio, Journal Year: 2024, Volume and Issue: 27, P. 101139 - 101139

Published: June 24, 2024

The prevalence of polymer usage in everyday activities has emerged as a detriment to both human life and the environment. A large number studies describe severe impacts micropolymers (MP) nanopolymers (NP) on various organ systems, including endocrine system. Additionally, plasticizers utilized additives have been identified endocrine-disrupting chemicals (EDCs). MP/NP, along with associated plasticizers, affect principal signalling pathways glands such pituitary, thyroid, adrenal, gonads, thereby disrupting hormone function metabolic processes crucial for maintaining homeostasis, fertility, neural development, fetal growth. This review delves into sources, distribution, effects micropolymers, nanopolymers, acting EDCs. Furthermore, it provides detailed mechanisms underlying disruption relation different types MP/NP.

Language: Английский

Citations

9
Exposure to polyethylene and polyvinylchloride microplastics caused advanced puberty onset in females through promoting hypothalamic GnRH expression DOI Creative Commons

Shaolian Zang,

Fei Wang, Yang Ouyang

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 291, P. 117906 - 117906

Published: Feb. 1, 2025

Precocious puberty (PP) is a common pediatric endocrine disorder that affects children's growth and sexual development. Environmental pollutants, especially microplastics (MPs), may be an important triggering factors in PP. MPs were widely found living environment, while the impact of on pubertal development remains unknown. In this study, 14 serum samples collected from central precocious (CPP) girls healthy controls. The concentration total CPP (68.19 ± 26.49 mg/kg) showed significant increase than controls (36.94 13.22 mg/kg). 5 11 types detected, among which PE (CPP, 28.22 %; Control, 31.62 %) PVC 62.67 58.14 being dominant ones. Correlation analysis between sex hormone revealed negatively correlated with progesterone positively dehydroepiandrosterone (DHEAS). order to investigate toxic effects onset, young female mice at 21 days orally administered various concentrations for two weeks. Female exposed (PE, 3 mg/day; PVC, 6 mg/day) had advanced vaginal opening, none changes body weight. Immunohistochemical staining demonstrated exposure during could activate microglia, astrocytes promote GnRH expression hypothalamus, leading earlier onset. These data suggested can absorbed accumulated brain gonad after gavage, accelerate initiation. This study provided valuable evidence threatened normal progression

Language: Английский

Citations

1
Subchronic co-exposure of polystyrene nanoplastics and 3-BHA significantly aggravated the reproductive toxicity of ovaries and uterus in female mice DOI
Guanghua Xiong, Haiyan Zhang, Yulin Peng

et al.

Environmental Pollution, Journal Year: 2024, Volume and Issue: 351, P. 124101 - 124101

Published: May 4, 2024

Language: Английский

Citations

8
Concerning influences of micro/nano plastics on female reproductive health: focusing on cellular and molecular pathways from animal models to human studies DOI Creative Commons

Hasti Balali,

Ali Morabbi,

Mohammad Karimian

et al.

Reproductive Biology and Endocrinology, Journal Year: 2024, Volume and Issue: 22(1)

Published: Nov. 11, 2024

The female reproductive system can face serious disorders and show abnormalities under the influence of environmental pollutants. Microplastics (MPs) nanoplastics (NPs) as emerging pollutants, by affecting different components this system, may make fertility a challenge. Animal studies have demonstrated that exposure to these substances weakens function ovaries causes decrease in ovarian reserve capacity. Also, continuous micro/nano plastics (MNPs) leads increased levels reactive oxygen species, induction oxidative stress, inflammatory responses, apoptosis granulosa cells, reduction number follicles. Furthermore, interfering with hypothalamic-pituitary-ovarian axis, particles disturb normal androgens endocrine balance delay growth gonads. Exposure MNPs accelerate carcinogenesis humans animal models. determined accumulate placenta, causing metabolic changes, disrupting development fetus, endangering health future generations. In humans, presence micro/nanoplastics placenta tissue, infant feces, breast milk has been reported. These directly affect mother increasing risk premature birth other pregnancy complications. This review aims outline hazardous effects on fetal discuss results experiments human research focusing cellular molecular pathways.

Language: Английский

Citations

6
Evaluation of the Spreading Dynamics and Interactions of Lead-Carrier Microplastics Affected by Biofilm: A Mini-Review DOI Creative Commons
Enes Özgenç

Water Air & Soil Pollution, Journal Year: 2024, Volume and Issue: 235(5)

Published: April 24, 2024

Abstract The toxic effect of microplastics (MPs) on living organisms is caused by the plastics and other pollutants attached to their surface. interaction MPs with hazardous such as lead (Pb) possible due large surface area high adsorption capacity heavy metals Pb. When combined metals, aquatic environments leads environmental biological problems. enter water, they form a biofilm under influence organic inorganic substances, significantly altering adsorption–desorption properties metal. current study aims understand Pb-MP investigating formation in MPs. By reviewing studies existing literature, analyses how affects behavior Pb metal Furthermore, future perspectives highlight potential research directions aiming fill knowledge gaps this field. Addressing challenges, it also highlights need for multidisciplinary approach understanding microplastic interactions ecosystems assess long-term effects these ecology health.

Language: Английский

Citations

5
Micro(nano)plastics: an Emerging Burden for Human Health DOI Creative Commons

Isabella Donisi,

Antonino Colloca,

Camilla Anastasio

et al.

International Journal of Biological Sciences, Journal Year: 2024, Volume and Issue: 20(14), P. 5779 - 5792

Published: Oct. 21, 2024

The escalation of plastic pollution represents a global environmental and health problem. Important toxic effects have been attributed to the increasing diffusion microplastics (MPs) nanoplastics (NPs) derived from degradation plastics. These particles ubiquitously observed in environment, with humans being continuously exposed via ingestion, inhalation skin contact. Nonetheless, cellular homeostasis imbalance induced by micro- nano- plastics (MNPs) human has only recently shown, while most evidence molecular mechanisms studies

Language: Английский

Citations

5