Hemodynamics of short-duration light-intensity physical exercise in the prefrontal cortex of children: a functional near-infrared spectroscopy study DOI Creative Commons
Takashi Naito, Koichiro Oka, Kaori Ishii

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: July 6, 2024

Abstract Identifying the types of exercise that enhance cerebral blood flow is crucial for developing programs cognitive function. Nevertheless, few studies have explored amount light-intensity, short-duration exercises individuals can easily perform on flow, particularly in children. We examined effects these hemodynamics prefrontal cortex (PFC) using functional near-infrared spectroscopy. Participants comprised 41 children (aged 12.1 ± 1.5 years, 37% female) who engaged seven light-intensity exercises, with each movement performed two patterns lasting 10 or 20 s. Changes oxygenated hemoglobin (oxy-Hb) levels at rest and during were compared analysis covariance, sex age as covariates. Significant increases oxy-Hb observed multiple regions PFC all forms (including dynamic twist stretching [66.6%, 8/12 regions, η 2 = 0.07–0.27], hand finger movements [75.0%, 9/12 0.07–0.16], balance (100.0%, 6/6 0.13–0.25]), except static monotonic movements. This study implies short-duration, provided they entail a certain degree and/or physical demands, activate increase flow.

Language: Английский

The Chain Mediating Effect of Anxiety and Inhibitory Control and the Moderating Effect of Physical Activity Between Bullying Victimization and Internet Addiction in Chinese Adolescents DOI
Yang Liu, J. Yin, Lei Xu

et al.

The Journal of Genetic Psychology, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 16

Published: Feb. 8, 2025

This study aimed to investigate the chain mediating roles of anxiety and inhibitory control in relationship between bullying victimization internet addiction among Chinese adolescents, as well moderating effect physical activity. A cross-sectional design was employed, sampling 1,585 adolescents from 5 provinces China during February–March 2024. Data on victimization, addiction, anxiety, control, activity were collected analyzed using a moderated mediation model. The data suggest that is associated with this association also mediated by control. Furthermore, found significantly moderate contributes understanding how are interrelated context development, influencing interplay. It highlights potential factor mitigating impact its addiction.

Language: Английский

Citations

5
Improving brain health via the central executive network DOI Open Access
Marcelo Bigliassi, Danylo F. Cabral, Amanda C. Evans

et al.

The Journal of Physiology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 24, 2025

Abstract Cognitive and physical stress have significant effects on brain health, particularly through their influence the central executive network (CEN). The CEN, which includes regions such as dorsolateral prefrontal cortex, anterior cingulate cortex inferior parietal lobe, is to managing demands of cognitively challenging motor tasks. Acute can temporarily reduce connectivity within leading impaired cognitive function emotional states. However a rebound in these states often follows, driven by motivational signals mesocortical mesolimbic pathways, help sustain inhibitory control task execution. Chronic exposure challenges leads long‐term improvements CEN functionality. These changes are supported neurochemical, structural systemic adaptations, including mechanisms tissue crosstalk. Myokines, adipokines, anti‐inflammatory cytokines gut‐derived metabolites contribute biochemical environment that enhances neuroplasticity, reduces neuroinflammation supports neurotransmitters serotonin dopamine. processes strengthen connectivity, improve self‐regulation enable individuals adopt health‐optimizing behaviours. Long‐term activity not only but also risk age‐related decline neurodegenerative diseases. This review highlights role progressive exercise practical approach strengthening promoting offering strategy resilience well‐being across lifespan. image

Language: Английский

Citations

1
Physical Exercise Counteracts Aging-Associated White Matter Demyelination Causing Cognitive Decline DOI Creative Commons

Tanya Butt,

Makoto Tobiume,

Diane B. Ré

et al.

Aging and Disease, Journal Year: 2024, Volume and Issue: 15(5), P. 2136 - 2136

Published: Jan. 1, 2024

In the central nervous system, oligodendrocytes wrap around neuronal axons to form myelin, an insulating layer or sheath that allows for efficient conductance of action potentials. addition structural insulation, myelin provides encased with nutrient, metabolic and defensive support. Demyelination, loss, can therefore cause axonal dysfunction, leading neurological impairment disease. Alzheimer's disease (AD), progressive white matter demyelination is acknowledged as one earliest pathologies preceding symptom onset. Unfortunately, current pharmacotherapy slowing promoting remyelination in AD nonexistent. Exercise recognized its wide-ranging benefits human health, including improved mental health prevention lifestyle-related diseases. Mounting evidence suggests contribution physical activity delaying progression dementia elderly populations. Recent mechanistic studies have shown exercise facilitates myelination brain through vitalization intrinsic pro-myelination cues, such increased neurotrophic factors electrical activity. this review, we summarize discuss potential on counteracting aging-associated demyelination, which causes cognitive decline AD. We highlight need further basic clinical research investigations topic establish novel approaches healthy aging.

Language: Английский

Citations

8
Physical exercise for brain plasticity promotion an overview of the underlying oscillatory mechanism DOI Creative Commons
Xueyang Li,

Xuehong Qu,

Kaixuan Shi

et al.

Frontiers in Neuroscience, Journal Year: 2024, Volume and Issue: 18

Published: Aug. 8, 2024

The global recognition of the importance physical exercise (PE) for human health has resulted in increased research on its effects cortical activity. Neural oscillations, which are prominent features brain activity, serve as crucial indicators studying PE function. Existing studies support idea that modifies various types neural oscillations. While EEG-related literature science exists, a comprehensive review specifically healthy populations not yet been conducted. Given demonstrated influence plasticity, particularly oscillatory it is imperative to consolidate this phenomenon. Therefore, aims summarize numerous neuromodulatory mechanisms over past decade, covering (1) resistance and aerobic training via oscillations; (2) how mind-body affects activity cognitive functioning; (3) age-Related neurodegenerative disease rehabilitation oscillation mechanisms; (4) conclusion future direction. In conclusion, effect multifaceted process, seeks comprehensively examine existing studies' understanding regulates brain, providing more scientific theoretical foundation development personalized programs further research.

Language: Английский

Citations

6
Peripheral to brain and hippocampus crosstalk induced by exercise mediates cognitive and structural hippocampal adaptations DOI

Gabriel Reichert Blume,

Luiz Fernando Freire Royes

Life Sciences, Journal Year: 2024, Volume and Issue: 352, P. 122799 - 122799

Published: June 7, 2024

Language: Английский

Citations

5
Longitudinal relationship between grip strength and cognitive function in a European population older than 50 years: A cross-lagged panel model DOI

Man Cui,

Juan Wang,

Miao Deng

et al.

Archives of Gerontology and Geriatrics, Journal Year: 2024, Volume and Issue: 122, P. 105396 - 105396

Published: March 5, 2024

Language: Английский

Citations

4
Physical activity patterns and cognitive function in elderly women: a cross-sectional study from NHANES 2011–2014 DOI Creative Commons
Junyu Wu, Peng Qiu,

Meihan Liu

et al.

Frontiers in Aging Neuroscience, Journal Year: 2024, Volume and Issue: 16

Published: June 12, 2024

Amid the backdrop of global aging, increasing prevalence cognitive decline among elderly, particularly within female demographic, represents a considerable public health concern. Physical activity (PA) is recognized as an effective non-pharmacological intervention for mitigating in older adults. However, relationship between different PA patterns and function (CF) elderly women remains unclear.

Language: Английский

Citations

4
Multi-omics uncovers immune-modulatory molecules in plasma contributing to resistance exercise-ameliorated locomotor disability after incomplete spinal cord injury DOI Creative Commons

Ren Zhou,

Jibao Chen,

Yunhan Tang

et al.

Genome Medicine, Journal Year: 2025, Volume and Issue: 17(1)

Published: Feb. 5, 2025

Exercise rehabilitation therapy has garnered widespread recognition for its beneficial effects on the restoration of locomotor function in individuals with spinal cord injury (SCI). Notably, resistance exercise demonstrated significant improvements muscle strength, coordination, and overall functional recovery. However, to optimize clinical management mimic exercise-like effects, it is imperative obtain a comprehensive understanding molecular alterations that underlie these positive effects. We conducted randomized controlled trial investigating incomplete SCI. integrated analysis plasma proteomics peripheral blood mononuclear cells (PBMC) transcriptomics explore cellular changes induced by exercise. Subsequently, we established weight-loaded ladder-climbing mouse model physiological exercise, analyzed proteome metabolome, as well transcriptomes PBMC tissue. Lastly, confirm transmissibility neuroprotective intravenously injected obtained from exercised male mice into SCI female during non-acute phase. Plasma proteomic transcriptomic profiling underscored notable involvement complement pathways humoral immune response process restoring following human trial. Moreover, was emphasized interventions could effectively modulate pathways. Through employing tissues mice, our study revealed immunomodulatory responses parallel those observed trials. In addition, metabolomics an enhancement lipid metabolism exhibited ameliorating disability after via reducing demyelination inhibiting neuronal apoptosis. Our investigation elucidates associated promoting recovery demonstrate direct delivered injection, which facilitates repair. Mechanistically, multi-omics involving both reveals principal constituents responsible within are predominantly immunoregulatory factors, warranting further experimental validation. The retrospectively registered 17 July, 2024, Chinese Clinical Trial Registry (No.: ChiCTR2400087038) at https://www.chictr.org.cn/ .

Language: Английский

Citations

0
Associations of oxidative balance score and cognition in US older adults: A cross-sectional study of National Health and Nutrition Examination Survey (NHANES) 2011 to 2014 DOI Creative Commons

Yue Jin,

Huajian Lin, Zegen Ye

et al.

Journal of Alzheimer s Disease Reports, Journal Year: 2025, Volume and Issue: 9

Published: Jan. 1, 2025

Background Oxidative stress is linked to cognitive decline in the elderly. Diet, as a key energy source, affects brain function and serves modifiable risk factor for decline. Objective This study investigates relationship between Balance Score (OBS), which reflects diet lifestyle impact on oxidative stress, older adults. Methods utilized data from National Health Nutrition Examination Survey (NHANES) 2011–2014, including 2716 participants aged 60 older. Cognitive outcomes measured were Consortium Establish Registry Alzheimer's Disease (CERAD) Word Learning test, Animal Fluency Digit Symbol Substitution test. Linear regression models used assess OBS performance, with stratification sensitivity analyses conducted explore these associations further. Results Among participants, higher dietary scores better test performance after adjusting confounders. For example, highest quartile had 4.35-point increase CERAD immediate recall compared lowest (OR: 4.35, 95% CI: 2.14–8.84, p = 0.001). Subgroup showed this positive association across age groups genders, though it was stronger among non-Hispanic white other racial groups. Conclusions Our findings indicate correlation adults, suggesting that an antioxidant-rich may help prevent population. However, since cross-sectional, further prospective research needed confirm results.

Language: Английский

Citations

0
THE ROLE OF MYOKINES IN IMPROVING COGNITIVE FUNCTION DOI Creative Commons
A.I. Petrova, Александр Викторович Марковский, Н. Л. Потапова

et al.

Zabajkalʹskij medicinskij vestnik, Journal Year: 2025, Volume and Issue: 4, P. 126 - 132

Published: Feb. 25, 2025

Over the past couple of decades, it has become apparent that skeletal muscles work as an endocrine organ can produce and secrete myokines exert their effects in endocrine, paracrine, or autocrine manner. Modern research shows physical exertion induces synthesis molecules involved transmission signals between muscle cells other organs, particular brain, adipose tissue, organs gastrointestinal tract, well skin vascular cells. This review examines cause communication with neuroprotection response to activity related processes. Unlike exercise-induced protective signaling pathways, inactivity wasting disrupt expression secretion and, turn, function central nervous system. It is assumed adapting from brain by modulating will help combat age-related neurodegeneration diseases affected systemic signals.

Language: Английский

Citations

0