Angewandte Chemie International Edition,
Journal Year:
2024,
Volume and Issue:
63(16)
Published: Feb. 23, 2024
Abstract
In
this
investigation,
we
explored
the
diversity
of
melleolide‐type
meroterpenoids
produced
by
Armillaria
ostoyae
,
one
largest
and
oldest
organisms
on
Earth,
using
extracts
from
liquid
solid
fermentation
media.
The
study
unveiled
three
unprecedented
dimeric
bismelleolides
novel
fatty‐acid‐substituted
congeners,
along
with
11
new
21
known
derivatives.
structures
were
elucidated
1D
2D
NMR
spectroscopy
HRESI‐MS,
ROESY
spectral
analysis
for
relative
configurations.
Absolute
configurations
determined
crystal
through
ECD
spectra
comparison.
A
compound
library
facilitated
metabolomics‐wide
associations,
revealing
production
patterns
under
different
culture
conditions.
enabled
assessments
antimicrobial
cytotoxic
activities,
that
Δ
2,4
double
bond
is
not
crucial
antifungal
activity.
Cytotoxicity
was
linked
to
presence
an
aldehyde
at
C1,
but
lost
hydroxylation
C13.
Chemoinformatic
analyses
demonstrated
intricate
interplay
chemical
modifications
biological
properties.
This
marks
first
systematic
exploration
spp.
meroterpenoid
MS‐based
untargeted
metabolomics,
offering
insight
into
structure–activity
relationships
innovative
chemoinformatics.
Fungal Diversity,
Journal Year:
2024,
Volume and Issue:
128(1), P. 1 - 165
Published: Oct. 15, 2024
Abstract
Fungi
are
one
of
the
most
diverse
groups
organisms
with
an
estimated
number
species
in
range
2–3
million.
The
higher-level
ranking
fungi
has
been
discussed
framework
molecular
phylogenetics
since
Hibbett
et
al.,
and
definition
higher
ranks
(e.g.,
phyla)
‘true
fungi’
have
revised
several
subsequent
publications.
Rapid
accumulation
novel
genomic
data
advancements
now
facilitate
a
robust
precise
foundation
for
classification
within
kingdom.
This
study
provides
updated
kingdom
,
drawing
upon
comprehensive
phylogenomic
analysis
Holomycota
which
we
outline
well-supported
nodes
fungal
tree
explore
more
contentious
groupings.
We
accept
19
phyla
Fungi,
viz
.
Aphelidiomycota
Ascomycota
Basidiobolomycota
Basidiomycota
Blastocladiomycota
Calcarisporiellomycota
Chytridiomycota
Entomophthoromycota
Entorrhizomycota
Glomeromycota
Kickxellomycota
Monoblepharomycota
Mortierellomycota
Mucoromycota
Neocallimastigomycota
Olpidiomycota
Rozellomycota
Sanchytriomycota,
Zoopagomycota
In
phylogenies,
Caulochytriomycota
resides
;
thus,
former
is
regarded
as
synonym
latter,
while
Caulochytriomycetes
viewed
class
provide
description
each
phylum
followed
by
its
classes.
A
new
subphylum,
Sanchytriomycotina
Karpov
introduced
only
subphylum
Sanchytriomycota
subclass
Pneumocystomycetidae
Kirk
al.
Pneumocystomycetes
invalid
thus
validated.
Placements
fossil
classes
also
discussed,
providing
examples.
Journal of Fungi,
Journal Year:
2024,
Volume and Issue:
10(1), P. 67 - 67
Published: Jan. 15, 2024
A
review
of
selected
studies
on
fungal
endophytes
confirms
the
paucity
Basidiomycota
and
basal
fungi,
with
almost
90%
attributed
to
Ascomycota.
Reasons
for
low
number
including
Chytridiomycota,
Mucoromycota,
Mortierellomycota,
are
advanced,
isolation
procedure
media,
incubation
period
slow
growth
basidiomycetes,
identification
non-sporulating
isolates,
endophyte
competition,
fungus–host
interactions.
We
compare
detection
through
culture-dependent
methods
culture-independent
methods,
role
fungi
senescence
host
plant,
next-generation
studies.
Journal of Fungi,
Journal Year:
2023,
Volume and Issue:
9(5), P. 523 - 523
Published: April 28, 2023
Transcriptional
regulation
is
vital
for
organismal
survival,
with
many
layers
and
mechanisms
collaborating
to
balance
gene
expression.
One
layer
of
this
genome
organization,
specifically
the
clustering
functionally
related,
co-expressed
genes
along
chromosomes.
Spatial
organization
allows
position
effects
stabilize
RNA
expression
transcription,
which
can
be
advantageous
a
number
reasons,
including
reductions
in
stochastic
influences
between
products.
The
co-regulated
families
into
functional
clusters
occurs
extensively
Ascomycota
fungi.
However,
less
characterized
within
related
Basidiomycota
fungi
despite
uses
applications
species
clade.
This
review
will
provide
insight
prevalence,
purpose,
significance
across
Dikarya,
foundational
studies
from
Ascomycetes
current
state
our
understanding
throughout
representative
Basidiomycete
species.
Frontiers in Veterinary Science,
Journal Year:
2023,
Volume and Issue:
10
Published: June 15, 2023
The
yaks
that
inhabit
the
Tibetan
plateau
are
a
rare
breed
is
closely
related
to
local
economic
development
and
human
civilization.
This
ancient
may
have
evolved
unique
gut
microbiota
due
hypoxic
high-altitude
environment.
susceptible
external
factors,
but
research
regarding
effects
of
different
feeding
models
on
fungal
community
in
remains
scarce.
In
this
study,
we
compared
analyzed
composition
variability
among
wild
(WYG),
house-feeding
domestic
(HFG),
grazing
(GYG).
results
revealed
Basidiomycota
Ascomycota
were
most
preponderant
phyla
community,
regardless
models.
Although
types
dominant
did
not
change,
their
abundances
did.
Intergroup
analysis
diversity
showed
Shannon
Simpson
indices
WYG
GYG
significantly
higher
than
those
HFG.
Fungal
taxonomic
there
20
genera
(Sclerostagonospora
Didymella)
between
GYG,
16
(Thelebolus
Cystobasidium)
Furthermore,
proportions
14
(Claussenomyces
Papiliotrema)
decreased,
whereas
eight
(Stropharia
Lichtheimia)
increased
HFG
as
GYG.
Taken
together,
study
indicated
structure
differ
raised
breeding
groups.
ABSTRACT
Long‐term
positioning
experiments
have
demonstrated
significant
benefits
in
agricultural
production
and
environmental
protection.
Faba
bean‐wheat
intercropping
with
nitrogen
fertiliser
can
effectively
mitigate
the
occurrence
of
faba
bean
wilt
disease.
Identifying
optimal
application
rate
is
essential
for
enhancing
disease
control
efficacy
intercropping.
This
study
aimed
to
investigate
long‐term
effects
varying
levels
on
physical,
chemical,
biological
changes
rhizosphere
soil
under
conditions
examine
their
relationship
incidence
In
a
9‐year
field
experiment,
two
treatments
1
year
(IF‐1)
9
years
(IF‐9)
were
established
four
(N0:
0
kg
ha
−1
;
N1:
45
N2:
90
N3:
135
).
Rhizosphere
from
plants
was
collected
assess
corresponding
indicators.
promoted
growth
controlled
by
improving
structure
fertility
quality
(SQI).
Under
different
levels,
certain
physical
properties
(moisture
content,
macroaggregate
proportion,
MWD,
GMD)
chemical
(SOM,
total
carbon,
SOC,
nutrients,
available
nutrients)
peaked
N2
(90
),
SQI
showing
similar
trend.
Additionally,
enhanced
enzyme
activity
rhizosphere,
reshaped
microbial
community
composition,
maximised
beneficial
microbes,
reduced
abundance
pathogenic
fungus
Fusarium,
achieved
N2.
at
significantly
improved,
enhanced,
plant
pathogens
modifying
composition.
alleviated
disease,
healthy
growth,
maintained
function.
