Journal of College of Physicians And Surgeons Pakistan,
Journal Year:
2023,
Volume and Issue:
unknown, P. 625 - 632
Published: June 1, 2023
Objective:
To
compile
a
comprehensive
national
cancer
registry
report
of
Pakistan
by
merging
and
analysing
registration
data
received
from
major
functional
registries
in
various
parts
Pakistan.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(13), P. 2007 - 2007
Published: June 25, 2024
Bovine
colostrum
provides
newborn
calves
with
strong
passive
immunity,
which
will
further
affect
the
immunity
of
their
offspring.
Compared
other
commercial
dairy
products,
bovine
emphasizes
limit
aflatoxin
M1,
pathogenic
bacteria,
microorganisms,
antibiotics,
stimulants,
and
items,
so
it
is
safe
to
use.
There
are
many
reports
that
use
as
a
breast
milk
fortifier
for
preterm
infants
necessary
immune
support
premature
infants,
but
selection
products
chosen
must
be
free
Bacillus
cereus
because
they
very
dangerous
infants.
This
also
used
in
more
clinical
research
needed.
At
same
time,
should
emphasized
composition
BC
different
from
human
colostrum,
particular,
main
protein
casein,
while
whey
protein,
especially
α-lactalbumin,
together
ovalbumin
still
reference
best
biological
value,
muscles.
Therefore,
currently
not
complete
substitute
milk.
In
recent
years,
addition
studies
have
found
has
immunomodulatory
promoting
effects
adolescents,
adults,
elderly.
suggests
potential
provide
appropriate
people
all
ages.
this
study
aimed
evaluate
quality
nutritional
characteristics
on
three
dimensions.
The
ages
narrative
review
identified
several
classes
immunoactive
substances
including
immunoglobulins,
cytokines,
enzymes,
compared
mature
milk,
full-term
demonstrate
rich
range
components.
addition,
influencing
factors
affecting
(immunoglobulin)
were
reviewed,
was
individual
differences,
environmental
factors,
processing
methods
had
great
impact
BC.
More
importantly,
reviewed
detail
(with
an
emphasis
immunocompromised
children
neonates)
evidence
hopes
above
make
understand
health
role
having
effect,
at
when
seeing
value
future,
limitations
its
application
deeply
re-explored,
such
lactose
intolerance,
allergies,
etc.,
effective
solutions
wide
colostrum.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(1), P. 160 - 160
Published: Jan. 3, 2024
In
the
context
of
nutrient-driven
epigenetic
alterations,
food-derived
miRNAs
can
be
absorbed
into
circulatory
system
and
organs
recipients,
especially
humans,
potentially
contribute
to
modulating
health
diseases.
Evidence
suggests
that
food
uptake,
by
carrying
exogenous
(xenomiRNAs),
regulates
individual
miRNA
profile,
modifying
redox
homeostasis
inflammatory
conditions
underlying
pathological
processes,
such
as
type
2
diabetes
mellitus,
insulin
resistance,
metabolic
syndrome,
cancer.
The
capacity
diet
control
levels
comprehension
unique
characteristics
dietary
in
terms
gene
expression
regulation
show
important
perspectives
a
strategy
disease
susceptibility
via
modifications
refine
clinical
outcomes.
However,
absorption,
stability,
availability,
roles
are
intriguing
currently
subject
intense
debate;
additionally,
there
is
restricted
knowledge
their
physiological
potential
side
effects.
Within
this
framework,
we
provided
up-to-date
comprehensive
on
miRNAs’
potential,
discussing
latest
advances
controversial
issues
related
role
human
modulators
chronic
syndromes.
Biological Procedures Online,
Journal Year:
2024,
Volume and Issue:
26(1)
Published: May 27, 2024
Abstract
Exosomes
are
increasingly
recognized
as
important
mediators
of
intercellular
communication
in
cancer
biology.
can
be
derived
from
cells
well
cellular
components
tumor
microenvironment.
After
secretion,
the
exosomes
carrying
a
wide
range
bioactive
cargos
ingested
by
local
or
distant
recipient
cells.
The
released
act
through
variety
mechanisms
to
elicit
multiple
biological
effects
and
impact
most
if
not
all
hallmarks
cancer.
Moreover,
owing
their
excellent
biocompatibility
capability
being
easily
engineered
modified,
currently
exploited
promising
platform
for
targeted
therapy.
In
this
review,
we
first
summarize
current
knowledge
roles
risk
etiology,
initiation
progression
cancer,
underlying
molecular
mechanisms.
aptamer-modified
exosome
therapy
is
then
briefly
introduced.
We
also
discuss
future
directions
emerging
biology
perspective
Journal of Cancer Research and Practice,
Journal Year:
2024,
Volume and Issue:
11(1), P. 7 - 17
Published: Jan. 1, 2024
Abstract
Objective:
Nutrition,
lifestyle
and
environment
are
the
main
factors
affecting
risk
of
cancer
global
burden
this
disease.
Although
these
generally
recognized
among
general
public
medical
professionals,
exact
root
causes
mechanisms
involved
not
clearly
defined
with
aim
control,
as
a
result,
incidence
rates
increasing
globally.
The
purpose
study
is
to
provide
an
overview
factors,
protective
measures
statistical
data
related
cancer,
considering
causes.
Data
Sources:
This
article
reviews
literature
address
most
important
control
associated
prevention
for
some
common
types
in
lung,
breast,
colon,
stomach,
prostate,
cervix,
skin.
Study
Selection:
To
have
reliable
interpretation,
latest
statistics
on
age-standardized
published
by
International
Agency
Research
Cancer
analyzed
according
specific
Results:
Understanding
provides
basis
more
effective
approaches
potential
strategies.
Conclusion:
Many
cases
controlled
nutritional,
environmental
identifying
effectively
controlling
can
be
significantly
reduced.
Journal of the American Nutrition Association,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 17
Published: Jan. 9, 2025
Breast
cancer
(BC)
is
one
of
the
leading
causes
death
and
morbidity
among
women
worldwide.
Epidemiologic
evidence
shows
that
risk
BC
other
chronic
diseases
decreases
as
proportion
whole
plant
foods
increases,
while
animal
(fish,
meat,
poultry,
eggs,
seafood,
dairy
products)
non–whole
(e.g.,
refined
grains,
added
sugars,
French
fries)
in
diet
decreases.
Whole
include
fruits,
vegetables,
roots,
tubers,
legumes,
nuts,
seeds
from
which
no
edible
part
has
been
removed
to
food
added.
A
lowers
insulin
resistance,
inflammation,
excess
body
fat,
cholesterol,
insulin-like
growth
factor
1
sex
hormone
bioavailability;
it
also
increases
estrogen
excretion,
induces
favorable
changes
gut
microbiota,
may
favorably
affect
mammary
microbiota
composition
decrease
early
menarche,
all
contributing
reduced
incidence,
recurrence,
mortality.
This
review
explores
connection
between
a
mortality
well
potential
mechanisms
involved.
Additionally,
this
compared
with
dietary
approaches
recommended
for
BC.
seems
optimal
pattern
overall
disease
prevention
exclusively
consists
which,
based
on
existing
evidence,
lead
best
health
outcomes.
Nutrients,
Journal Year:
2025,
Volume and Issue:
17(3), P. 394 - 394
Published: Jan. 22, 2025
Background:
The
Middle
East
and
North
Africa
(MENA)
region
is
witnessing
a
continuous
rise
in
the
incidence
of
breast
cancer
(BC).
This
characterized
by
distinct
cultural
lifestyle
habits.
Despite
importance
diet
as
modifiable
risk
factor
for
BC,
its
role
development
BC
within
MENA
context
has
not
been
extensively
studied.
systematic
review
aims
to
identify
synthesize
existing
evidence
regarding
effect
different
dietary
factors
on
among
women
from
this
region.
Methods:
We
systematically
reviewed
scientific
literature
observational
studies
that
examined
association
between
specific
MENA,
accordance
with
Preferred
Reporting
Items
Systematic
Reviews
Meta-Analyses
(PRISMA)
statement.
Our
comprehensive
search
included
databases
such
PubMed,
Web
Science,
ScienceDirect,
Scopus,
identified
total
18,085
records,
which
65
met
our
inclusion
criteria
were
assessed
quality
using
National
Institute
Health
Quality
Assessment
Tool.
Results:
findings
categorized
into
food
groups,
nutrients,
patterns.
Studies
have
consistently
shown
consumption
fruit
vegetables,
fish
seafood,
black
tea
are
associated
reduced
risk.
In
contrast,
intake
milk
white
bread
linked
an
increased
Specific
patterns
Mediterranean
diet,
healthy
plant-based
antioxidant
index,
overall
negative
Conversely,
insulin
index
load,
glycemic
inflammatory
unhealthy
BC.
For
remaining
factors,
research
was
too
limited
or
inconsistent
draw
conclusions.
Conclusions:
highlight
significant
modulating
region,
area
faces
notable
gap
topic.
Further
essential
deepen
understanding
develop
targeted
recommendations
prevention
population.
