Climate friendly MOFs synthesis for drug delivery systems by integrating AI, intelligent manufacturing, and quantum solutions in industry 6.0 sustainable approach DOI
M. Akhtar, Hammad Majeed, Tehreema Iftikhar

et al.

Toxicology Research, Journal Year: 2024, Volume and Issue: 14(1)

Published: Dec. 31, 2024

Abstract Since the Industrial Revolution, ecological damage, ecosystem disruption, and climate change acceleration have frequently resulted from human advancement at price of environment. Due to rise in illnesses, Industry 6.0 calls for a renewed dedication sustainability with latest technologies. Focused research creative solutions are needed achieve UN Sustainable Development Goals (SDGs), especially 3, 9, 13, 14, 15, 17. A promising sustainable technology enhancing healthcare while reducing environmental effect is Metal Organic Frameworks (MOFs). MOFs perfect drug administration because their high surface areas, adjustable pore sizes, remarkable drug-loading capacities. They created by combining advanced artificial intelligence, intelligent manufacturing, quantum computing. Researchers can create functional groups or ligands that bind selectively target cells tissues, minimizing off-target effects, thanks distinct benefits families like MIL, HKUST, UiO, ZIF etc. offer targeted delivery. Combining other nanomaterials results multipurpose systems handle challenging biomedical issues. Despite its promise, there still issues MOFs’ possible toxicity long-term stability physiological settings. To advance medicinal applications, these problems must be resolved. increase usefulness medicine critically analysing limitations putting up alternatives. The creation technologies (additive manufacturing etc.) delivery prime example how scientific stewardship may coexist provide advantageous both people

Language: Английский

Precision-Engineered Construction of Proton-Conducting Metal–Organic Frameworks DOI Creative Commons
Liyu Zhu,

Hongbin Yang,

Ting Xu

et al.

Nano-Micro Letters, Journal Year: 2024, Volume and Issue: 17(1)

Published: Dec. 11, 2024

Proton-conducting materials have attracted considerable interest because of their extensive application in energy storage and conversion devices. Among them, metal-organic frameworks (MOFs) present tremendous development potential possibilities for constructing novel advanced proton conductors due to special advantages crystallinity, designability, porosity. In particular, several design strategies the structure MOFs opened new doors advancement MOF conductors, such as charged network construction, ligand functionalization, metal-center manipulation, defective engineering, guest molecule incorporation, pore-space manipulation. With implementation these strategies, proton-conducting developed significantly profoundly within last decade. Therefore, this review, we critically discuss analyze fundamental principles, methods targeted at improving conductivity through representative examples. Besides, structural features, conduction mechanism behavior are discussed thoroughly meticulously. Future endeavors also proposed address challenges practical research. We sincerely expect that review will bring guidance inspiration further motivate research enthusiasm materials.

Language: Английский

Citations

18
Recent advances in COF-based framework: Synthesis, Potential application, Current challenges and Future direction DOI
Zeeshan Ajmal, Simon Kizito,

Basem Alalwan

et al.

Materials Today Chemistry, Journal Year: 2024, Volume and Issue: 39, P. 102140 - 102140

Published: June 13, 2024

Language: Английский

Citations

17
3D-Printed MOF Monoliths: Fabrication Strategies and Environmental Applications DOI Creative Commons
Hossein Molavi, Kamyar Mirzaei, Mahdi Barjasteh

et al.

Nano-Micro Letters, Journal Year: 2024, Volume and Issue: 16(1)

Published: Aug. 15, 2024

Metal-organic frameworks (MOFs) have been extensively considered as one of the most promising types porous and crystalline organic-inorganic materials, thanks to their large specific surface area, high porosity, tailorable structures compositions, diverse functionalities, well-controlled pore/size distribution. However, developed MOFs are in powder forms, which still some technical challenges, including abrasion, dustiness, low packing densities, clogging, mass/heat transfer limitation, environmental pollution, mechanical instability during process, that restrict applicability industrial applications. Therefore, recent years, attention has focused on techniques convert MOF powders into macroscopic materials like beads, membranes, monoliths, gel/sponges, nanofibers overcome these challenges.Three-dimensional (3D) printing technology achieved much interest because it can produce many high-resolution with complex shapes geometries from digital models. this review summarizes combination different 3D strategies MOF-based for fabricating 3D-printed monoliths applications, emphasizing water treatment gas adsorption/separation Herein, various fabrication such direct ink writing, seed-assisted in-situ growth, coordination replication solid precursors, matrix incorporation, selective laser sintering, light processing, described relevant examples. Finally, future directions challenges also presented better plan trajectories shaping improved control over structure, composition, textural properties monoliths.

Language: Английский

Citations

14
Continuous and selective recovery of fluorobenzene from complex water emulsion by superhydrophobic wood mimetic cryogel DOI
Xinqi Wang, Jiani Xu, Xiaoli Huang

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 159710 - 159710

Published: Jan. 1, 2025

Language: Английский

Citations

0
Industrialization of Covalent Organic Frameworks DOI
Kaiyuan Wang,

Xueling Qiao,

Hongxia Ren

et al.

Journal of the American Chemical Society, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 27, 2025

Covalent organic frameworks (COFs) have attracted broad interest because of their well-defined, customizable, highly stable, and porous structures. COFs shown significant potential for various practical applications, such as gas storage/purification, drug purification, water treatment, catalysis, battery applications. Scaling up is desirable to meet industrial application demands but hindered by the limitations synthesis methods high cost reactants. Recently, emerging green methods, mechanochemical flux synthesis, offered promising solutions these challenges (e.g., ton-scale production has been achieved companies recently). This Perspective provides an overview state art with respect discusses factors influencing large-scale COFs. Directions opportunities improving performance sustainability toward applications are also emphasized.

Language: Английский

Citations

0
Application of 3D Printing Technology in Dentistry: A Review DOI Open Access

Yangqing Chen,

Junchao Wei

Polymers, Journal Year: 2025, Volume and Issue: 17(7), P. 886 - 886

Published: March 26, 2025

Three-dimensional (3D) printing is a cutting-edge technology that widely used in biomedical fields to construct various commercial products or scaffolds for theoretical research. In this review, 3D technologies with different principles are briefly introduced, including selective laser melting (SLM), sintering (SLS), fused deposition modeling (FDM), stereolithography (SLA), and digital light processing (DLP). addition, the applications of dentistry, such as dental implantology, prosthodontics, orthodontics, maxillofacial surgery, tissue regeneration, were summarized. Furthermore, perspective challenges also addressed help readers obtain clear map development dentistry.

Language: Английский

Citations

0
3D‐Printed In Situ Growth of Bilayer MOF Hydrogels for Accelerated Osteochondral Defect Repair DOI

Kaiqi Qin,

Xinyue Huang, Shengfeng Wang

et al.

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 17, 2024

Abstract Repairing osteochondral (OC) defect presents a significant challenge due to the intricate structural requirements and unpredictable differentiation pathways of bone marrow mesenchymal stem cells (BMSCs). To address this challenge, novel biomimetic OC hydrogel scaffold is developed that features structure soft hard components. This incorporates bilayer metal–organic frameworks (MOFs), specifically ZIF‐67 in upper layer ZIF‐8 lower layer, achieved through an situ printing process. configuration enables spatial temporal modulation BMSC by controlling release Co 2 ⁺ Zn ⁺. The results demonstrate MOF hydrogels significantly outperform either lack MOFs or contain single type enhancing repair outcomes rabbit models knee defects. improved regenerative efficacy attributed distinct chondrogenic osteogenic cues provided MOFs, effectively guiding BMSCs toward enhanced tissue regeneration. customizable not only opens new avenues for innovative therapeutic strategies but also holds great promise widespread clinical applications.

Language: Английский

Citations

2
Macrophage membrane-encapsulated miRNA nanodelivery system for the treatment of hemophilic arthritis DOI

Yufan Qian,

Yan Ma, Atanas Banchev

et al.

Journal of Controlled Release, Journal Year: 2024, Volume and Issue: 377, P. 632 - 647

Published: Nov. 29, 2024

Language: Английский

Citations

2
Application of 3D Printing Technology in Microreactor Fabrication DOI
Jinhao Zheng, Yifan Niu,

Ziyu Song

et al.

JOM, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 4, 2024

Language: Английский

Citations

1
Climate friendly MOFs synthesis for drug delivery systems by integrating AI, intelligent manufacturing, and quantum solutions in industry 6.0 sustainable approach DOI
M. Akhtar, Hammad Majeed, Tehreema Iftikhar

et al.

Toxicology Research, Journal Year: 2024, Volume and Issue: 14(1)

Published: Dec. 31, 2024

Abstract Since the Industrial Revolution, ecological damage, ecosystem disruption, and climate change acceleration have frequently resulted from human advancement at price of environment. Due to rise in illnesses, Industry 6.0 calls for a renewed dedication sustainability with latest technologies. Focused research creative solutions are needed achieve UN Sustainable Development Goals (SDGs), especially 3, 9, 13, 14, 15, 17. A promising sustainable technology enhancing healthcare while reducing environmental effect is Metal Organic Frameworks (MOFs). MOFs perfect drug administration because their high surface areas, adjustable pore sizes, remarkable drug-loading capacities. They created by combining advanced artificial intelligence, intelligent manufacturing, quantum computing. Researchers can create functional groups or ligands that bind selectively target cells tissues, minimizing off-target effects, thanks distinct benefits families like MIL, HKUST, UiO, ZIF etc. offer targeted delivery. Combining other nanomaterials results multipurpose systems handle challenging biomedical issues. Despite its promise, there still issues MOFs’ possible toxicity long-term stability physiological settings. To advance medicinal applications, these problems must be resolved. increase usefulness medicine critically analysing limitations putting up alternatives. The creation technologies (additive manufacturing etc.) delivery prime example how scientific stewardship may coexist provide advantageous both people

Language: Английский

Citations

0