Chronobiology International,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 10
Published: May 8, 2025
We
performed
a
systematic
review
evaluating
evidence
regarding
whether/which
24-h
sleep-wake
characteristics
(e.g.
sleep,
activity
levels,
and
rhythms)
related
to
worse
BPSDs.
searched
PubMed
for
cross-sectional
observational
studies
of
people
with
dementia
examining
relationships
between
actigraphy-measured
sleep/wake
factors
BPSDs
(search
completed
June
2024).
used
the
JBI
checklists
assess
risk
bias
summarize
results
within
subcategories
(sleep,
level,
rhythm)
BPSD
(composite,
agitation,
apathy,
mood/affect)
dimensions.
Thirteen
articles
met
inclusion
criteria.
Measures
inactivity
were
most
frequently
examined
correlated
with:
(a)
greater
apathy
(6/6
studies);
(b)
depression
(only
in
bivariate
analyses
1
study);
(c)
more
agitation
(2/3
(d)
higher
composite
scores
(1/2
studies).
All
six
measuring
sleep
duration
failed
identify
associations
Studies
continuity
measures
generally
found
associations,
i.e.
(1
study),
studies),
mood
study).
rhythm
variables
mixed
no
association
Actigraphy
are
associated
dementia.
Due
relatively
low
numbers
articles,
future
needed
confirm
if
inactivity,
issues,
disruption,
timing
independently
relate
BPSDs,
changes
objective
measures,
e.g.
increase
following
intervention,
signal/mediate
improvements
Medicina,
Journal Year:
2024,
Volume and Issue:
60(2), P. 216 - 216
Published: Jan. 26, 2024
Neuroscience
applied
to
motor
activity
is
a
growing
area
that
aims
understand
the
effects
of
on
structures
and
functions
Central
Nervous
System.
Attention
has
been
paid
this
multidisciplinary
field
investigation
by
scientific
community
both
because
it
great
importance
in
treatment
many
chronic
diseases
its
potential
applications
Movement
Sciences.
Motor
during
developmental
age
is,
fact,
an
indispensable
tool
for
physical
mental
growth
children,
able-bodied
disabled.
Through
movement,
individuals
can
improve
their
efficiency
promote
own
better
health,
establish
relationships
with
environment
others,
express
themselves
emotions,
form
identity
develop
cognitive
processes.
This
literature
review
aims,
therefore,
highlight
how
adequate
practice
offers
extraordinary
possibilities
everyone
relation
learning,
from
perspective
integral
development
person,
and,
consequently,
raise
awareness
those
involved
training
growth,
especially
youngest,
towards
educational
value
sports
activities.
According
review,
line
modern
neuroscientific
approach
toward
between
activities
functions,
possible
claim
hypokinesia
tends
inhibit
learning.
Therefore,
now
seems
more
topical
than
ever
draw
attention
need
introduce
working
proposals
integrate
brain-based
programs
into
school
curriculum.
European Journal of Cancer Prevention,
Journal Year:
2024,
Volume and Issue:
34(1), P. 24 - 39
Published: May 29, 2024
Physical
activity
(PA)
has
an
established
role
in
the
promotion
of
health
and
fitness
prevention
disease.
Expected
overall
benefits
include
reduction
all-cause
morbidity
death,
weight
control,
improved
quality
life,
bone
decreased
falls
elderly
subjects,
,
deeper
cognition,
reduced
risk
depression,
anxiety,
sleeplessness.
Currently,
PA
is
a
mainstay
management
cardiovascular
diseases,
metabolic
syndrome,
diabetes,
health.
Recently,
perception
its
primary
secondary
prevention,
interception,
treatment
cancer,
however,
also
gaining
importance.
Regular
walking,
simplest
type
PA,
associated
with
disease
mortality,
cancer
increasing
interest.
Furthermore,
improves
life
patients,
attenuating
side
effects
chemotherapy,
decreasing
sarcopenia,
fitness,
inhibiting
recurrence
progression
some
types.
It
promotes
emotional
psychological
inducing
positive
changes.
While
mechanisms,
effective
levels
useful
amount
practice
are
well
cardiology,
they
yet
to
be
fully
determined
oncology.
Nevertheless,
recommended
reduce
general
population,
it
been
introduced
programs
for
second
cancers.
In
perspective,
will
help
as
integrative
therapy
patients
survivors.
The
number
beneficial
continuum
highlighted
this
review.
Annals of Neurology,
Journal Year:
2024,
Volume and Issue:
96(4), P. 633 - 649
Published: Aug. 17, 2024
Alzheimer's
disease
(AD)
is
a
devastating,
age‐associated
neurodegenerative
disorder
and
the
most
common
cause
of
dementia.
The
clinical
continuum
AD
spans
from
preclinical
to
subjective
cognitive
decline,
mild
impairment,
dementia
stages
(mild,
moderate,
severe).
Neuropathologically,
defined
by
accumulation
amyloid
β
(Aβ)
into
extracellular
plaques
in
brain
parenchyma
cerebral
vasculature,
abnormally
phosphorylated
tau
that
accumulates
intraneuronally
forming
neurofibrillary
tangles
(NFTs).
Development
treatment
approaches
prevent
or
even
reduce
decline
because
has
been
slow
compared
other
major
causes
death.
Recently,
United
States
Food
Drug
Administration
gave
full
approval
2
different
Aβ‐targeting
monoclonal
antibodies.
However,
this
breakthrough
modifying
approach
only
applies
limited
subset
patients
there
are
stringent
eligibility
criteria.
Furthermore,
these
do
not
progression
disease,
AD‐related
pathologies,
such
as
NFTs,
directly
targeted.
A
non‐mutually
exclusive
alternative
address
lifestyle
interventions
can
help
risk
dementias
(ADRD).
It
estimated
addressing
modifiable
factors
could
potentially
delay
up
40%
AD/ADRD
cases.
In
review,
we
discuss
some
many
may
be
associated
with
prevention
and/or
increasing
resilience,
well
interact
influence
progression.
[Color
figure
viewed
at
www.annalsofneurology.org
]
ANN
NEUROL
2024;96:633–649
Alzheimer s & Dementia,
Journal Year:
2024,
Volume and Issue:
20(7), P. 4747 - 4764
Published: May 29, 2024
The
combination
of
exergame-based
motor-cognitive
training
with
resonance
breathing
guided
by
heart-rate
variability
biofeedback
(HRV-BF)
targets
various
relevant
mechanisms
action
to
alleviate
the
pathological
state
in
mild
neurocognitive
disorders
(mNCD).
Psychology Research and Behavior Management,
Journal Year:
2024,
Volume and Issue:
Volume 17, P. 101 - 116
Published: Jan. 1, 2024
Background:
Studies
in
old
adults
showed
bidirectional
interconnections
between
amnestic
mild
cognitive
impairment
(aMCI)
and
affective
symptoms
that
adverse
childhood
experiences
(ACE)
may
affect
both
factors.
Nevertheless,
these
associations
be
confined
to
older
with
clinical
depression.
Aim:
To
delineate
the
relationship
of
aMCI
without
major
depression
(MDD)
or
dysfunctions
activities
daily
living
(ADL).
Methods:
This
case-control
study
recruited
61
participants
(diagnosed
using
Petersen's
criteria)
59
excluded
subjects
MDD
ADL
dysfunctions.
Results:
We
uncovered
2
distinct
dimensions,
namely
distress
age
(DSOA),
comprising
symptoms,
perceived
stress
neuroticism,
dysfunctions,
episodic
memory
test
scores,
total
Mini-Mental
State
Examination
(MMSE)
Montreal
Cognitive
Assessment
(MoCA)
scores.
A
large
part
variance
(37.9%)
DSOA
scores
was
explained
by
ACE,
negative
life
events
(health
financial
problems),
a
subjective
feeling
decline,
education
(all
positively).
ACE
NLE
have
highly
significant
impact
on
score
are
not
associated
its
severity.
Cluster
analysis
diagnosis
is
overinclusive
because
some
incorrectly
classified
as
aMCI.
Conclusion:
The
clinicians
should
carefully
screen
for
after
excluding
MDD.
might
misinterpreted
Keywords:
depression,
experiences,
impairments,
disorders,
events,
neurocognitive
deficits
Aging Clinical and Experimental Research,
Journal Year:
2024,
Volume and Issue:
36(1)
Published: April 23, 2024
Physical
inactivity
is
an
important,
but
potentially
reversible
risk
factor
for
dementia
and
mild
cognitive
impairment
(MCI).
There
literature
about
physical
activity
exercise
the
prevention
management
of
MCI,
this
had
not
been
previously
synthesized
into
specific
guidelines
topic.
A
recent
guideline
on
in
MCI
was
published,
authored
by
several
international
societies,
including
lay
representatives.
In
commentary,
we
discuss
implications
guidance
healthcare
professionals,
caregivers,
representatives
involved
care
people
with
dementia.The
highlight
importance
cognitively
healthy
persons
at
different
stages
these
conditions.
For
primary
dementia,
may
be
suggested
persons.
mind-body
interventions,
such
as
yoga,
have
greatest
evidence,
whilst
role
requires
more
evidence
from
high-quality
randomized
controlled
trials.
living
moderately
severe
useful
maintaining
function.
are
benefits
separate
their
impact
outcomes.
The
also
proposed
some
questions
future
research.
conclusion,
there
limited
beneficial
preserving
functions
subjects
normal
cognition,
or
dementia.
support
promotion
based
effects
almost
all
facets
health.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(19), P. 3421 - 3421
Published: Oct. 9, 2024
Due
to
the
continuous
aging
of
population
and
consequent
increase
in
dementia,
focus
on
its
prevention
is
growing
importance
for
public
health.
Since
effective
pharmacological
treatments
are
not
yet
available,
other
determinants
cognitive
decline
have
become
fundamental.
Several
studies
indicated
that
Mediterranean
diet
(MedDiet)
associated
with
reduced
incident
but
few
been
conducted
persons
already
diagnosed
Alzheimer’s
disease
(AD).
We
age-matched
73
patients
mild–moderate
AD
controls
(mean
age
whole
group
=
76.5
±
6.5;
67.5%
women).
The
cases
had
a
significantly
lower
adherence
MedDiet
physical
activity
vs.
controls,
where
only
one
participant
(1.4%)
high
among
compared
5.5%
while
52.5%
moderate
82.2%
controls.
In
multivariate
analysis,
presence
was
Other
factors
examined
(gender,
age,
level,
multimorbidity,
polypharmacy)
were
MedDiet.
Thus,
low
very
activity.
Public
health
strategies
aimed
at
promoting
older
people
should
be
priority.
International Journal of Hygiene and Environmental Health,
Journal Year:
2025,
Volume and Issue:
264, P. 114521 - 114521
Published: Jan. 13, 2025
Evidence
on
the
impact
of
complex
neighborhood
environment,
including
air
pollution,
greenness,
and
socioeconomic
deprivation
(nSED)
cognitive
health
in
older
adults
remains
scarce.
Both
cognition
environment
are
associated
with
physical
activity,
but
little
is
known
about
potential
mediating
role
activity
this
association.
Cross-sectional
data
Czech
arm
HAPIEE
cohort
study
examined
4,178
participants
(55.6%
women)
aged
45-69
years.
Global
score
was
constructed
from
memory,
verbal
fluency,
concentration
domains.
The
exposures,
assigned
to
participant's
addresses,
include
4-year
(2000-2003)
average
concentrations
PM2.5,
greenness
index
calculated
tree
crown
canopy
cover
estimation
(2000),
census-based
nSED
characteristics.
Physical
other
covariates
were
assessed
by
a
questionnaire.
Structural
equation
modelling
used
estimate
standardized
β
coefficients
for
relationships
between
performance.
After
controlling
range
covariates,
global
function
inversely
PM2.5
(β
=
-0.087;
95%CI:
0.122
-0.052)
-0.147;
0.182
-0.115),
positively
0.036;
0.001
0.069).
We
identified
weak
statistically
significant
associations
exposures
score.
Total
mediation
proportions
ranged
3.9%
6.5%
respectively.
individuals;
partially
mediated
activity.
World Psychiatry,
Journal Year:
2025,
Volume and Issue:
24(1), P. 150 - 151
Published: Jan. 15, 2025
Preventive
psychiatry
is
a
comprehensive
field
within
that
encompasses
the
prevention
of
mental
disorders
and
promotion
health.
Clinically,
it
applies
across
lifespan,
at
any
stage
illness,
bio-psycho-social
framework.
It
transcends
psychiatric
subspecialties
equally
relevant
to
fields
such
as
public
health
policy.
The
significance
preventive
profound:
estimates
based
on
2019
Global
Burden
Disease
study
suggest
account
for
up
16%
global
disability-adjusted
life
years
(DALYs),
with
associated
costs
ranging
from
4
8%
national
gross
domestic
product,
depending
region.
A
considerable
portion
this
burden
potentially
preventable,
secondary
tertiary
interventions
capable
reducing
clinical
progression
disability,
thereby
also
alleviating
economic
impact.
Mental
promotion,
arguably
even
more
critical
than
disorders,
addresses
entire
population,
focusing
enhancing
quality
rather
being
nosocentric.
These
considerations
explain
why
central
focus
current
WPA
Action
Plan1,
has
been
in
all
Plans
2014
2024.
Section
Psychiatry
seeks
increase
visibility
promote
its
adoption
practice,
research,
education
Between
2024,
made
significant
progress
toward
these
aims.
First,
organized
symposia
World
Congresses
since
2014,
contributed
over
50
presentations
co-sponsored
other
international
meetings.
themes
addressed
included
"International
issues
psychiatry"
(World
Congress,
Madrid
2014),
"Preventive
psychiatry,
substance
misuse,
early
intervention"
(WPA
meeting,
Athens
2015),
"Disasters
–
context
responses"
Belgrade
2016),
community"
Berlin
2017),
primary
care"
Lisbon
2019),
"Mental
emerging
adulthood:
facets
prevention"
Bangkok
2021),
"Diagnostics,
treatment
eating
disorders"
Moscow
2022),
"Prevention
detection
psychosis"
thematic
conference,
Alzheimer's
disease",
"Non-pharmacological
strategies
maintaining
older
adults",
"Psychosis
prevention:
latest
updates
real-life
practice"
Vienna
2023).
conducted
research
projects,
Education
Prevention
Intersectional
Project
(EPIC),
collaboration
Education,
which
reviewed
teaching
curricula
medical
schools
worldwide.
This
project
surveyed
530
schools,
revealing
vast
majority
did
not
include
their
curricula,
less
3%
mentioning
subject
all.
findings,
though
entirely
surprising,
underscored
urgent
need
psychiatry.
We
then
explored
potential
using
conceptual
foundation
school
curricula.
perspective
was
elaborated
book
chapter
WPA's
Advances
Psychiatry,
Vol.
(2019)2,
where
argued
offers
distinct
educational
advantages
due
relevance
medicine,
alignment
key
outcomes
(especially
attitudes),
inclusion
essential
skills
communication,
reflective
capacity,
empathy.
integrative
anti-stigma
further
reinforces
value.
Guideline
development
Section.
European
Psychiatric
Association
(EPA)
guidance
crises
Europe
(2016)3,
provided
evidence-based
recommendations
effects
financial
crises;
guidelines
role
exercise
dementia
(2023)4,
large
consortium
initiative
emphasized
necessity
effective
prevention.
Guidelines
preventing
psychosis
individuals
high
risk
are
currently
under
review.
published
20
journal
papers
chapters
past
decade,
covering
interface
areas
including
consultation-liaison
psychiatry5,
schizophrenia6,
misuse7,
crises8,
person-centered
medicine9,
child
adolescent
psychiatry10,
among
others.
Finally,
participated
two
consortia
Union
Horizon
2020
projects.
Overall,
productive
decade
Psychiatry.
Its
active
members
dedicated
leadership
well
equipped
continue
advancing
application
supporting
integration
into
training,
promoting
by
policy
makers.