Bioprinting of self-healing materials and nanostructures for biomedical applications: Recent advances and progresses on fabrication and characterization techniques
Bioprinting,
Journal Year:
2024,
Volume and Issue:
38, P. e00335 - e00335
Published: Feb. 1, 2024
Language: Английский
Biomaterials-based hydrogels for therapeutic applications
IntechOpen eBooks,
Journal Year:
2024,
Volume and Issue:
unknown
Published: May 23, 2024
Conventional
therapeutic
models
based
on
the
premise
of
a
universal
solution
are
facing
decrease
in
efficiency,
emphasized
by
large
number
patients
who
show
resistance
or
do
not
respond
positively
to
classic
treatments.
This
perspective
highlights
urgency
for
more
precise
approaches
personalized
treatments
that
adaptable
specific
complexities
and
unique
challenges
faced
each
patient.
Hydrogels
biocompatible
biodegradable
systems
well-controlled
targeted
administration
agents,
being
formed
3D
reticulated
networks
water-soluble
polymeric
biomaterials,
natural,
synthetic,
hybrid
origin,
with
intrinsic
extrinsic
properties.
Due
easily
adjustable
porous
structure,
hydrogels
allow
encapsulation
macromolecular
drugs,
proteins,
small
molecules,
cells,
hormones,
growth
factors
gel
matrix
their
subsequent
controlled
release.
The
biomaterials
used,
crosslinking
methods,
design,
functionalization
strategies
obtaining
improved
properties
presented.
different
possibilities
application
described
transdermally,
as
dressing
materials,
oral,
ocular,
spray-able,
injectable,
up
intracellular
level.
chapter
extensively
investigates
advances
advantages
enable
effective,
noninvasive,
provide
greater
patient
comfort
wide
range
applications.
Language: Английский
On the design of lignin reinforced acrylic acid/hyaluronic acid adhesive hydrogels with conductive PEDOT:HA nanoparticles
International Journal of Biological Macromolecules,
Journal Year:
2024,
Volume and Issue:
273, P. 133093 - 133093
Published: June 12, 2024
Hydrogels
are
of
great
importance
in
biomedical
engineering.
They
possess
the
ability
to
mimic
bodily
soft
tissues,
and
this
allows
exciting
possibilities
for
applications
such
as
tissue
engineering,
drug
delivery
wound
healing,
however
much
work
remains
on
stability
mechanical
robustness
allow
translation
clinical
applications.
The
herein
describes
synthesis
analysis
a
biocompatible,
versatile
hydrogel
that
has
tailorable
swelling,
high
when
swollen
thermal
stability.
methods
used
produce
with
elasticity,
good
properties
rapid
crosslinking
whilst
displaying
biocompatibility,
adhesion,
conductivity.
It
been
shown
cell
viability
samples
is
above
80
%
all
cases,
Young's
Modulus
up
85
kPa
swelling
degrees
were
achieved.
These
materials
show
potential
use
numerous
adhesive
sensors,
skin
grafts
systems.
Language: Английский
Biomaterials Mimicking Mechanobiology: A Specific Design for a Specific Biological Application
Leonardo Donati,
No information about this author
Maria Luisa Valicenti,
No information about this author
Samuele Giannoni
No information about this author
et al.
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(19), P. 10386 - 10386
Published: Sept. 26, 2024
Mechanosensing
and
mechanotransduction
pathways
between
the
Extracellular
Matrix
(ECM)
cells
form
essential
crosstalk
that
regulates
cell
homeostasis,
tissue
development,
morphology,
maintenance,
function.
Understanding
these
mechanisms
involves
creating
an
appropriate
support
elicits
signals
to
guide
cellular
functions.
In
this
context,
polymers
can
serve
as
ideal
molecules
for
producing
biomaterials
designed
mimic
characteristics
of
ECM,
thereby
triggering
responsive
closely
resemble
those
induced
by
a
natural
physiological
system.
The
generated
specific
stimuli
depend
on
different
or
synthetic
origins
polymers,
chemical
composition,
assembly
structure,
physical
surface
properties
biomaterials.
This
review
discusses
most
widely
used
their
customization
develop
with
tailored
properties.
It
examines
how
biomaterials-based
be
harnessed
replicate
functions
biological
cells,
making
them
suitable
biomedical
biotechnological
applications.
Language: Английский
Electrically Conductive Lignin Reinforced Polyacrylic Acid/Hyaluronic Acid Scaffolds With PEDOT:HA Nanoparticles
Polymers for Advanced Technologies,
Journal Year:
2024,
Volume and Issue:
35(10)
Published: Oct. 1, 2024
ABSTRACT
Hydrogel
materials
are
continually
developing
in
biomedical
engineering
and
recently
a
lot
of
effort
has
gone
into
their
engineered
performance
physiological
applications.
Porosity
is
an
important
characteristic
for
tissue
scaffolds
to
allow
enhanced
biocompatibility
the
pore
size
needed
dependent
on
application
type
which
hydrogel
being
used
regenerate.
Regarding
applications,
use
conducting
polymers
gaining
popularity
due
promising
potential
stimulate
cell
growth
proliferation
through
electrical
stimulation.
Building
previous
development
by
authors,
this
study
focuses
biocompatible
scaffold
with
adjustable
porosity
swelling
capabilities,
robust
mechanical
properties,
conductivity,
high
thermal
stability.
The
objective
work
examine
effect
freezing
temperature,
cross‐linker
final
characteristics
then
determine
possible
porosity,
degree,
compression
strength,
biocompatibility,
material
were
analyzed
found
be
affected
varied
synthesis
methods
used.
Overall,
synthesized
exhibit
good
increased
fluorescence
over
3
days
70%
viability,
stability
up
200°C
range
1725%
8472%.
They
also
portray
properties
Young's
Moduli
11
kPa
4.54
MPa
0.78–71.98
μm
depending
Through
variations
methods,
highly
porous,
absorbent,
stable
have
been
synthesized.
Notably,
single
recipe
tailorable
applications
from
drug
delivery
wound
repair.
Language: Английский