Synthesis lectures on emerging engineering technologies, Journal Year: 2025, Volume and Issue: unknown, P. 35 - 49
Published: Jan. 1, 2025
Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(2), P. 695 - 695
Published: Feb. 18, 2023
Modern drug discovery methods led to evolving new agents with significant therapeutic potential. However, their properties, such as solubility and administration-related challenges, may hinder benefits. Moreover, advances in biotechnology resulted the development of a generation molecules short half-life that necessitates frequent administration. In this context, controlled release systems are required enhance treatment efficacy improve patient compliance. Innovative delivery promising tools protect proteins peptides against proteolytic degradation where is achievable. The present review provides an overview different approaches used for delivery.
Language: Английский
Citations
70
Biomaterials Science, Journal Year: 2024, Volume and Issue: 12(7), P. 1643 - 1661
Published: Jan. 1, 2024
Electrospun nanofibers with fascinating properties provide a versatile platform for postoperative tissue anti-adhesion.
Language: Английский
Citations
24
Cellulose, Journal Year: 2024, Volume and Issue: 31(4), P. 2221 - 2238
Published: Feb. 5, 2024
Abstract Membranes find applications across a wide spectrum of industries, including water treatment, energy production, and biomedicine. In this study, nonwoven membranes were fabricated using cellulose acetate (CA) as the primary component, with varying percentages nanofibers (CNFs) embedded reinforcement. These CNFs prepared through an oxalic acid pretreatment (Oxalic-CNFs). Their incorporation into electrospun represents innovative approach, enhancing their mechanical properties for subjected to high loads improving its functionalization capabilities. The impact Oxalic-CNFs on membrane was investigated at nanofiber loadings ranging from 0 18 wt%. produced 6 wt% Oxalic-CNF exhibited superior physical properties. This improvement can be attributed formation threads higher intrinsic strength, reduction in pore size, increase density. When added, not properly formed, because filaments continuous needle became clogged. substructure proved critical factor properties, remarkable increases tensile strength elastic modulus (around 300%) when comparing 4–6 Oxalic-CNF-loaded CA membranes.
Language: Английский
Citations
17
Small, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 5, 2025
Abstract Bacterial infections are a significant obstacle to the healing of acute and chronic wounds, such as diabetic ulcers burn injuries. Traditional antibiotics primary treatment for bacterial infections, but they present issues antibiotic resistance, limited efficacy, potential side effects. This challenge leads exploration nanozymes alternative therapeutic agents. Nanozymes nanomaterials with enzyme‐like activities. Owing their low production costs, high stability, scalability, multifunctionality, have emerged prominent focus in antimicrobial research. Among various types nanozymes, metal‐based offer several benefits, including broad‐spectrum activity robust catalytic properties. Specifically, copper‐based (CuNZs) shown considerable promoting wound healing. They exhibit strong effects, reduce inflammation, enhance tissue regeneration, making them highly advantageous use care. review describes dual functions CuNZs combating infection facilitating repair. Recent advancements design synthesis CuNZs, evaluating promotion, biosafety both vitro vivo on basis core components, critically important.
Language: Английский
Citations
2
ACS Materials Letters, Journal Year: 2023, Volume and Issue: 5(6), P. 1627 - 1648
Published: May 4, 2023
In the past decades, rapid development of Internet Things (IoT) technology and artificial intelligence (AI) has driven research boom physical sensors. Material selection, structure design, performance for sensors have attracted extensive attention from worldwide researchers in field advanced manufacturing. Significant technological progress been made area applications various fields such as electronic skin, biomedicine, tissue engineering. There are many methods (e.g., electrospinning, screen printing, or rotary coating) to prepare Among them, nanofibers nanofiber membranes prepared by electrospinning advantages a nanosize effect, high specific surface area, porosity over other reported materials used this review, working principles including pressure sensors, strain temperature humidity first introduced; recent electrospun nanofiber-based is then summarized. Finally, future trends associated challenges large-scale adoption proposed.
Language: Английский
Citations
32
Bioengineering, Journal Year: 2024, Volume and Issue: 11(3), P. 218 - 218
Published: Feb. 25, 2024
Cardiovascular disease (CVD) remains the leading cause of mortality worldwide. In particular, patients who suffer from ischemic heart (IHD) that is not amenable to surgical or percutaneous revascularization techniques have limited treatment options. Furthermore, after successfully implemented, there are a number pathophysiological changes myocardium, including but ischemia-reperfusion injury, necrosis, altered inflammation, tissue remodeling, and dyskinetic wall motion. Electrospinning, nanofiber scaffold fabrication technique, has recently emerged as an attractive option potential therapeutic platform for cardiovascular disease. Electrospun scaffolds made biocompatible materials ability mimic native extracellular matrix compatible with drug delivery. These inherent properties, combined ease customization low cost production, electrospun active area research this review, we aim discuss current state electrospinning fundamentals creation role both bioengineered matrices delivery vehicles in CVD, special emphasis on clinical applications myocardial ischemia.
Language: Английский
Citations
14
Materials Today Chemistry, Journal Year: 2024, Volume and Issue: 38, P. 102109 - 102109
Published: May 24, 2024
Language: Английский
Citations
12
ACS Applied Bio Materials, Journal Year: 2024, Volume and Issue: 7(7), P. 4231 - 4253
Published: June 10, 2024
Electrospun polymeric nanofibers are essential in various fields for applications because of their unique properties. Their features similar to extracellular matrices, which suggests them healthcare fields, such as antimicrobials, tissue engineering, drug delivery, wound healing, bone regeneration, and biosensors. This review focuses on the synthesis electrospun nanofibers, surface modification, biomedical applications. Nanofibers can be fabricated from both natural synthetic polymers composites. Even though they mimic (physicochemical characteristics) not always capable fulfilling purpose target application. Therefore, need improved via modification techniques. Both needle-based needleless electrospinning thoroughly discussed. Various techniques setups employed each method also reviewed. Furthermore, pre- postspinning approaches including instrument design targeted applications, extensively In this way, remarkable potential highlighted reveal future research directions dynamic field.
Language: Английский
Citations
12
Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 94, P. 105482 - 105482
Published: Feb. 15, 2024
Language: Английский
Citations
11
RSC Advances, Journal Year: 2024, Volume and Issue: 14(26), P. 18536 - 18552
Published: Jan. 1, 2024
Bacterial infections and antibiotic resistance have posed a severe threat to public health in recent years. One emerging promising approach this issue is the photocatalytic sterilization of nanohybrids. By utilizing ZnO sterilization, drawbacks conventional antibacterial treatments can be efficiently addressed. This study examines enhanced sterilizing effectiveness Fe-doped nanoparticles (Fe-ZnO nanohybrids) incorporated into polymer membranes that are active visible light. Using co-precipitation procedure, Fe-ZnO nanohybrids (Fe
Language: Английский
Citations
11