Recent Advancements on Photothermal Conversion and Antibacterial Applications over MXenes-Based Materials

Nano-Micro Letters, Journal Year: 2022, Volume and Issue: 14(1)

Published: Aug. 24, 2022

The pernicious bacterial proliferation and emergence of super-resistant bacteria have already posed a great threat to public health, which drives researchers develop antibiotic-free strategies eradicate these fierce microbes. Although enormous achievements been achieved, it remains an arduous challenge realize efficient sterilization cut off the drug resistance generation. Recently, photothermal therapy (PTT) has emerged as promising solution efficiently damage integrity pathogenic based on hyperthermia beyond their tolerance. Until now, numerous agents studied for antimicrobial PTT. Among them, MXenes (a type two-dimensional transition metal carbides or nitrides) are extensively investigated one most candidates due high aspect ratio, atomic-thin thickness, excellent performance, low cytotoxicity, ultrahigh dispersibility in aqueous systems. Besides, application scenarios using antibacterial properties can be tailored via elaborated designs MXenes-based materials. In this review, synthetic approaches textural systematically presented first, then mechanisms materials documented. Subsequently, recent progress diverse fields making use performances well summarized reveal potential applications various purposes, including vitro vivo sterilization, solar water evaporation purification, flexible fabrics. Last but not least, current challenges future perspectives discussed provide theoretical guidance fabrication systems MXenes.

Language: Английский

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Nanomaterials and nanomaterials-based drug delivery to promote cutaneous wound healing

Advanced Drug Delivery Reviews, Journal Year: 2022, Volume and Issue: 193, P. 114670 - 114670

Published: Dec. 17, 2022

Language: Английский

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Functional nano-systems for transdermal drug delivery and skin therapy

Nanoscale Advances, Journal Year: 2023, Volume and Issue: 5(6), P. 1527 - 1558

Published: Jan. 1, 2023

Functional nano-systems have been applied as a promising strategy for transdermal drug delivery and skin therapy.

Language: Английский

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Advances in preparation and application of antibacterial hydrogels

Journal of Nanobiotechnology, Journal Year: 2023, Volume and Issue: 21(1)

Published: Aug. 26, 2023

Bacterial infections, especially those caused by drug-resistant bacteria, have seriously threatened human life and health. There is urgent to develop new antibacterial agents reduce the problem of antibiotics. Biomedical materials with good antimicrobial properties been widely used in applications. Among them, hydrogels become focus research field biomedical due their unique three-dimensional network structure, high hydrophilicity, biocompatibility. In this review, latest progresses about recent years were summarized, mainly including preparation methods According different mechanisms, several representative introduced, such as antibiotics loaded hydrogels, antibiotic-free metal-based peptide polymers, stimuli-responsive smart light-mediated hydrogels. addition, we also discussed applications challenges biomedicine, which are expected provide directions ideas for application clinical therapy.

Language: Английский

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Recent design strategies for boosting chemodynamic therapy of bacterial infections

Exploration, Journal Year: 2023, Volume and Issue: 4(2)

Published: Oct. 17, 2023

Abstract The emergence of drug‐resistant bacteria poses a significant threat to people's lives and health as bacterial infections continue persist. Currently, antibiotic therapy remains the primary approach for tackling infections. However, escalating rates drug resistance coupled with lag in development novel drugs have led diminishing effectiveness conventional treatments. Therefore, nonantibiotic‐dependent therapeutic strategies has become imperative impede rise resistance. chemodynamic (CDT) opened up new possibility due CDT can convert H 2 O into •OH via Fenton/Fenton‐like reaction treatment. efficacy is limited by variety practical factors. To overcome this limitation, sterilization efficiency be enhanced introducing therapeutics inherent antimicrobial capability. In addition, researchers explored CDT‐based combined therapies augment its effects mitigate potential toxic side toward normal tissues. This review examines research progress field, explores various enhance presents synergistic combination other modalities. And last, current challenges faced future directions are discussed.

Language: Английский

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Microneedles for Enhanced Topical Treatment of Skin Disorders: Applications, Challenges, and Prospects

Engineering, Journal Year: 2023, Volume and Issue: unknown

Published: June 1, 2023

Microneedles (MNs) can be used for the topical treatment of skin disorders as they directly deliver therapeutics to site lesions, resulting in increased therapeutic efficacy while having minimum side effects. MNs are different kinds (e.g., small molecules, macromolecules, nanomedicines, living cells, bacteria, and exosomes) treating various disorders, including superficial tumors, wounds, infections, inflammatory diseases, abnormal appearance. The improved by integrating advantages multiple perform combination therapy. Through careful designing, further modified with biomimetic structures responsive drug release from internal external stimuli enhance transdermal delivery efficiency robust outcomes. Some studies have proposed use drug-free a promising mechanotherapeutic strategy promote wound healing, scar removal, hair regeneration via mechanical communication pathway. Although several advantages, practical application suffers problems related industrial manufacture clinical evaluation, making it difficult translation. In this study, we summarized applications, emerging challenges, developmental prospects provide information on ways advance

Language: Английский

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MXene: A wonderful nanomaterial in antibacterial

Frontiers in Bioengineering and Biotechnology, Journal Year: 2024, Volume and Issue: 12

Published: Feb. 1, 2024

Increasing bacterial infections and growing resistance to available drugs pose a serious threat human health the environment. Although antibiotics are crucial in fighting infections, their excessive use not only weakens our immune system but also contributes resistance. These negative effects have caused doctors be troubled by clinical application of antibiotics. Facing this challenge, it is urgent explore new antibacterial strategy. MXene has been extensively reported tumor therapy biosensors due its wonderful performance. Due large specific surface area, remarkable chemical stability, hydrophilicity, wide interlayer spacing, excellent adsorption reduction ability, shown potential for biopharmaceutical applications. However, there few antimicrobial evaluations on MXene. The current mechanisms mainly include physical damage, induced oxidative stress, photothermal photodynamic therapy. In paper, we reviewed MXene-based composites discussed guide further research field.

Language: Английский

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Progress, Prospects and Challenges of MXene Integrated Optoelectronics Devices

ChemElectroChem, Journal Year: 2024, Volume and Issue: 11(8)

Published: March 7, 2024

Abstract Recently, the emerging 2D materials MXene have gained a surge of attention to production optoelectronics devices such as solar cells, plasmonic, phototransistors, photodetectors, light‐emitting diodes, photothermal therapy, and so on. Its outstanding optical electrical characteristics, unique structure, large specific surface area make it suitable for future use in modern including ultrafast lasers, light emitters, modulators, plasmonic generators. There is lack critical analysis on prospects, challenges, overview synthesis methods, mechanisms, research directions despite having some reviews been published applications MXene. Therefore, this study critically analyzed existing challenges MXene, poor stability an oxygen environment, inadequate mechanical properties, ease stacking, temperature barrier, In addition, fundamentals, preparation techniques, summarized. The mechanism, limitations, benefits different methods mentioned. A comprehensive guidelines provided improve methods. ways overcome these markets MXene‐based optoelectronic described.

Language: Английский

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Phototherapy-based multifunctional nanoplatform for synergistic therapy against drug resistance bacteria: Progress, advances and challenges

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 487, P. 150705 - 150705

Published: March 25, 2024

Language: Английский

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Multifunctional flexible MXene/TA@CNC electronic hydrogel patch with robust adhesion and self-healing properties for wearable electronics

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: 507, P. 160329 - 160329

Published: Feb. 7, 2025

Language: Английский

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