Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2024, Volume and Issue: 327, P. 125347 - 125347
Published: Oct. 28, 2024
Language: Английский
Chemical Reviews, Journal Year: 2024, Volume and Issue: 124(5), P. 2699 - 2804
Published: Feb. 29, 2024
The ability to gain spatiotemporal information, and in some cases achieve control, the context of drug delivery makes theranostic fluorescent probes an attractive intensely investigated research topic. This interest is reflected steep rise publications on topic that have appeared over past decade. Theranostic probes, their various incarnations, generally comprise a fluorophore linked masked drug, which released as result certain stimuli, with both intrinsic extrinsic stimuli being reported. release then signaled by emergence signal. Importantly, use appropriate fluorophores has enabled not only this emerging fluorescence marker for but also provided modalities useful photodynamic, photothermal, sonodynamic therapeutic applications. In review we highlight recent work particular focus are activated tumor microenvironments. We summarize efforts develop other applications, such neurodegenerative diseases antibacterials. celebrates diversity designs reported date, from discrete small-molecule systems nanomaterials. Our aim provide insights into potential clinical impact still-emerging direction.
Language: Английский
Citations
138
Advanced Materials, Journal Year: 2023, Volume and Issue: unknown
Published: Aug. 10, 2023
Rapid advancements in materials science and nanotechnology, intertwined with oncology, have positioned photothermal therapy (PTT) as a promising noninvasive treatment strategy for cancer. The breast's superficial anatomical location aesthetic significance render breast cancer particularly pertinent candidate the clinical application of PTT following melanoma. This review comprehensively explores research conducted on various types nanoparticles employed elaborates their specific roles mechanisms action. integration existing therapies is scrutinized, underscoring its potential synergistic outcomes. Additionally, underlying consequential modifications to tumor microenvironment after are elaborated from medical perspective. Future directions suggested, an emphasis development integrative platforms that combine multiple therapeutic approaches optimization nanoparticle synthesis enhanced efficacy. goal push boundaries toward comprehensive, clinically applicable
Language: Английский
Citations
85
ACS Nano, Journal Year: 2024, Volume and Issue: 18(18), P. 11560 - 11572
Published: April 29, 2024
Second near-infrared (NIR-II) carbon dots, with absorption or emission between 1000 and 1700 nm, are gaining increasing attention in the biomaterial field due to their distinctive properties, which include straightforward preparation processes, stable photophysical characteristics, excellent biocompatibility, low cost. As a result, there is growing focus on controlled synthesis modulation of photochemical properties NIR-II aim further expand biomedical applications, current research hotspot. This account aims provide comprehensive overview recent advancements dots within field. The review will cover following topics: (i) design, synthesis, purification (ii) surface modification strategies, (iii) particularly domain cancer theranostics. Additionally, this addresses challenges encountered by outline future directions realm By exploring carbon-based biomaterials, we can anticipate that contribution garner increased contribute development next-generation advanced functional thereby offering enhanced tools strategies
Language: Английский
Citations
17
International Journal of Thermal Sciences, Journal Year: 2024, Volume and Issue: 200, P. 108998 - 108998
Published: March 2, 2024
Language: Английский
Citations
7
Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 517, P. 216006 - 216006
Published: June 18, 2024
Language: Английский
Citations
7
Journal of Nanobiotechnology, Journal Year: 2023, Volume and Issue: 21(1)
Published: May 9, 2023
Photothermal therapy (PTT) in the second near-infrared (NIR-II) window has attracted extensive attention due to benefits high maximum permissible exposure and penetration depth. Current photothermal agents generally show a broadband absorption accompanied by gradual attenuation of NIR-II window, leading poor effect PTT. It remains great challenge gain with strong characteristic regions. To overcome this problem, based on carbon dots (CDs)-mediated growth strategy, we proposed simple feasible approach prepare plasmonic gold nanodendrites (AuNDs) enhance therapeutic
Language: Английский
Citations
14
Sensors and Actuators B Chemical, Journal Year: 2023, Volume and Issue: 385, P. 133705 - 133705
Published: March 21, 2023
Language: Английский
Citations
13
Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 408, P. 135522 - 135522
Published: Feb. 23, 2024
Language: Английский
Citations
6
Materials Chemistry and Physics, Journal Year: 2023, Volume and Issue: 297, P. 127345 - 127345
Published: Jan. 5, 2023
Language: Английский
Citations
12
Analytical Chemistry, Journal Year: 2024, Volume and Issue: 96(21), P. 8689 - 8695
Published: May 15, 2024
Tumor microenvironment-responsive phototheranostic agents are highly sought after for their ability to improve diagnostic accuracy and treatment specificity. Here, we introduce a novel single-molecule probe, POZ-NO, which is activated by nitric oxide (NO) weak acidity, enabling dual-mode imaging photothermal therapy (PTT) of tumors. In acidic environments with elevated NO levels, POZ-NO exhibits distinctive ratiometric fluorescence signal shift from the red near-infrared, accompanied 700 nm photoacoustic signal. Additionally, demonstrated potent effects upon acidity activation, achieving an impressive conversion efficiency 74.3% under 735 laser irradiation. vivo studies confirm POZ-NO's accurately image tumors through modes while selectively treating PTT.
Language: Английский
Citations
4