Biosensors,
Journal Year:
2023,
Volume and Issue:
13(2), P. 175 - 175
Published: Jan. 22, 2023
Electrochemical
biosensors,
in
which
enzymatic
biofuel
cells
simultaneously
work
as
energy
power
and
signal
generators,
have
become
a
research
hotspot.
They
display
the
merits
of
self-support,
simplified
structure,
vivo
operational
feasibility,
online
timely
monitoring,
etc.
Since
concept
cell-powered
biosensors
(EBFC-SPBs)
was
first
proposed,
its
applications
health
monitoring
scored
tremendous
achievements.
However,
creation
practical
application
portable
EBFC-SPBs
are
still
impeded
by
difficulty
their
miniaturization.
In
recent
years,
booming
microfluidic
technology
has
powerfully
pushed
forward
progress
made
miniaturized
EBFC-SPBs.
This
brief
review
recalls
summarizes
achievements
addition,
we
also
discuss
advantages
challenges
that
screen-printing
technologies
provide
to
wearable
disposable
ACS Sustainable Chemistry & Engineering,
Journal Year:
2023,
Volume and Issue:
11(6), P. 2209 - 2218
Published: Feb. 3, 2023
We
report
on
a
flexible,
bifunctional
platform
made
with
solution-blow
spinning
fiber
mats
of
polylactic
acid
(PLA)
and
polyethylene
glycol
(PEG).
The
PLA/PEG
were
designated
because
they
used
as
substrate
for
screen-printed
carbon
electrodes
(SPCEs)
matrix
to
attach
glucose
oxidase
(GOx)
covalently.
By
attaching
GOx
only
the
mats,
not
SPCE,
detection
hydrogen
peroxide
generated
from
oxidation
by
enzyme
was
efficient,
especially
Prussian
blue
(PB)
nanoparticles
electrodeposited
SPCE
surface.
device
detected
(H2O2)
in
synthetic
human
urine
at
low
applied
potential
(0
V
vs
Ag/AgCl)
range
1.0
6.0
mM,
limit
0.197
being
also
interference-free.
biosensor
whose
cost
is
Materials Chemistry Frontiers,
Journal Year:
2023,
Volume and Issue:
7(16), P. 3278 - 3297
Published: Jan. 1, 2023
A
flexible
sensor
is
a
key
part
of
intelligent
wearable
devices.
The
design
micro–nano
structured
materials
in
sensors
crucial.
Therefore,
the
recent
application
devices
summarized.
Polymers,
Journal Year:
2023,
Volume and Issue:
15(6), P. 1389 - 1389
Published: March 10, 2023
To
treat
and
manage
chronic
diseases,
it
is
necessary
to
continuously
monitor
relevant
biomarkers
modify
treatment
as
the
disease
state
changes.
Compared
other
bodily
fluids,
interstitial
skin
fluid
(ISF)
a
good
choice
for
identifying
because
has
molecular
composition
most
similar
blood
plasma.
Herein,
microneedle
array
(MNA)
presented
extract
ISF
painlessly
bloodlessly.
The
MNA
made
of
crosslinked
poly(ethylene
glycol)
diacrylate
(PEGDA),
an
optimal
balance
mechanical
properties
absorption
capability
suggested.
Besides,
effect
needles'
cross-section
shape
on
penetration
studied.
integrated
with
multiplexed
sensor
that
provides
color
change
in
biomarker
concentration-dependent
manner
based
reactions
colorimetric
detection
pH
glucose
biomarkers.
developed
device
enables
diagnosis
by
visual
inspection
or
quantitative
red,
green,
blue
(RGB)
analysis.
outcomes
this
study
show
can
successfully
identify
matter
minutes.
home-based
long-term
monitoring
management
metabolic
diseases
will
benefit
from
such
practical
self-administrable
detection.
Advanced Materials,
Journal Year:
2024,
Volume and Issue:
36(30)
Published: May 11, 2024
Wearable
bioelectronics
represents
a
significant
breakthrough
in
healthcare
settings,
particularly
(bio)sensing
which
offers
an
alternative
way
to
track
individual
health
for
diagnostics
and
therapy.
However,
there
has
been
no
notable
improvement
the
field
of
cancer,
skin
cancer.
Here,
wearable
bioelectronic
patch
is
established
transdermal
sensing
melanoma
biomarker,
tyrosinase
(Tyr),
using
microneedle
array
integrated
with
surface-bound
chemo-responsive
smart
probe
enable
target-specific
electrochemical
detection
Tyr
directly
from
human
tissue.
The
results
presented
herein
demonstrate
feasibility
sensor
direct
quantification
enzyme
biomarkers
ex
vivo
model.
Initial
performance
analysis
proves
that
designed
methodology
can
be
fast
reliable
diagnosis
evaluation
moles.
innovative
approach
here
may
revolutionize
landscape
monitoring
by
offering
nondisruptive
means
continuous
surveillance
timely
intervention
anomalies,
such
as
inflammatory
diseases
or
allergies
extended
screening
multiple
responses
complementary
simple
modification
device
design.
Advanced Healthcare Materials,
Journal Year:
2022,
Volume and Issue:
12(1)
Published: Oct. 27, 2022
Novel
biomaterials
for
bio-
and
chemical
sensing
applications
have
gained
considerable
traction
in
the
diagnostic
community
with
rising
trends
of
using
biocompatible
lowly
cytotoxic
material.
Hydrogel-based
electrochemical
sensors
become
a
promising
candidate
their
swellable,
nano-/microporous,
aqueous
3D
structures
capable
immobilizing
catalytic
enzymes,
electroactive
species,
whole
cells,
complex
tissue
models,
while
maintaining
tunable
mechanical
properties
wearable
implantable
applications.
With
advances
highly
controllable
fabrication
processability
these
novel
biomaterials,
possibility
bio-nanocomposite
hydrogel-based
presents
paradigm
shift
development
biocompatible,
"smart,"
sensitive
health
monitoring
point-of-care
devices.
Here,
recent
hydrogels
detection
biomarkers
vitro,
situ,
vivo
are
briefly
reviewed
to
demonstrate
applicability
ideal
conditions,
cellular
environments,
live
animal
respectively,
provide
comprehensive
assessment
whether
ready
translation
biointegration.
Sensors
based
on
conductive
nonconductive
polymers
presented,
highlights
nano-/microstructured
electrodes
that
enhanced
sensitivity
selectivity
matrices.
An
outlook
current
challenges
shall
be
addressed
realization
truly
continuous
real-time
platforms
is
also
presented.
