Magnetic Nanoparticles: A Comprehensive Review from Synthesis to Biomedical Frontiers DOI

Shlok Mishra,

Manishkumar D. Yadav

Langmuir, Journal Year: 2024, Volume and Issue: 40(33), P. 17239 - 17269

Published: Aug. 12, 2024

Nanotechnology has opened new doors of exploration, particularly in materials science and healthcare. Magnetic nanoparticles (MNP), the tiny magnets, because their various properties, have potential to bring about radical changes field medicine. The distinctive surface chemistry, nontoxicity, biocompatibility, and, particular, inducible magnetic moment attracted a great deal interest morphological structures from variety scientific domains. This review presents concise overview MNPs crucial properties synthesis routes. It also aims highlight continuous methods available for MNP production. In recent years, use computational understanding behavior been on rise. Thus, we discuss numerical models developed understand how can be used hyperthermia targeting Circle Wilis. With increasing biomedical applications, it becomes necessary mechanisms toxicity, which are elucidated this review. focuses applications drug delivery, theranostics, MRI contrasting agents. We anticipate that article will broaden perspective help functionality applicability better.

Language: Английский

Emerging Nanoparticle-Based Diagnostics and Therapeutics for Cancer: Innovations and Challenges DOI Creative Commons

Rachitha Puttasiddaiah,

Nagaraj Basavegowda,

Nityashree Kyathegowdanadoddi Lakshmanagowda

et al.

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(1), P. 70 - 70

Published: Jan. 7, 2025

Malignant growth is expected to surpass other significant causes of death as one the top reasons for dismalness and mortality worldwide. According a World Health Organization (WHO) study, this illness approximately between 9 10 million instances deaths annually. Chemotherapy, radiation, surgery are three main methods treating cancer. These seek completely eradicate all cancer cells while having fewest possible unintended impacts on healthy cell types. Owing lack target selectivity, majority medications have substantial side effects. On hand, nanomaterials transformed identification, diagnosis, management Nanostructures with biomimetic properties been grown late, fully intent observing sickness. nanostructures be consumed by in areas profound disease. Furthermore, because their extraordinary physicochemical properties, which incorporate nanoscale aspects, more prominent surface region, explicit geometrical features, ability embody different substances within or outside surfaces, remarkable nano-vehicles conveying restorative specialists designated regions. This review discusses recent developments nanostructured materials such graphene, dendrimers, cell-penetrating peptide nanoparticles, nanoliposomes, lipid magnetic nano-omics diagnosis

Language: Английский

Citations

2

Conjugating magnetic nanoparticles anisotropy to their dipolar interactions: Effect on the hyperthermic losses index via micromagnetic simulations DOI
Νikolaos Μaniotis,

Maria Gitsou,

Michael Maragakis

et al.

Journal of Magnetism and Magnetic Materials, Journal Year: 2025, Volume and Issue: unknown, P. 172843 - 172843

Published: Feb. 1, 2025

Language: Английский

Citations

2

New Green Approaches in Nanoparticles Synthesis: An Overview DOI Creative Commons
Bogdan Andrei Miu,

Anca Dinischiotu

Molecules, Journal Year: 2022, Volume and Issue: 27(19), P. 6472 - 6472

Published: Oct. 1, 2022

Nanotechnology is constantly expanding, with nanomaterials being more and used in common commercial products that define our modern life. Among all types of nanomaterials, nanoparticles (NPs) occupy an important place, considering the great amount produced nowadays diversity their applications. Conventional techniques applied to synthesize NPs have some issues impede them from appreciated as safe for environment health. The alternative these might be use living organisms or biological extracts can involved green approach synthesis NPs, a process free harmful chemicals, cost-effective low energy consumer. Several factors, including reducing agent concentration, initial precursor salt agitation, reaction time, pH, temperature light, influence characteristics biologically synthesized NPs. interdependence between parameters was not explored, main impediment implementation method on industrial scale. Our aim present brief review focuses current knowledge regarding how aforementioned factors control size shape green-synthesized We also provide overview biomolecules were found suitable NP synthesis. This work meant support researchers who intend develop new approaches

Language: Английский

Citations

66

Magnetite Nanoparticles: Synthesis and Applications in Optics and Nanophotonics DOI Open Access
N.O. Dudchenko, Shweta Pawar, Ilana Perelshtein

et al.

Materials, Journal Year: 2022, Volume and Issue: 15(7), P. 2601 - 2601

Published: April 1, 2022

Magnetite nanoparticles with different surface coverages are of great interest for many applications due to their intrinsic magnetic properties, nanometer size, and definite morphology. widely used medical-biological while usage in optics is not as widespread. In recent years, nanomagnetite suspensions, so-called ferrofluids, applied magneto-optical properties. This review gives an overview synthesis its addition, the preparation application nanofluids optics, nanophotonics, imaging described.

Language: Английский

Citations

63

Room-Temperature Chemiresistive Gas Sensing of SnO2 Nanowires: A Review DOI

Vraj Shah,

Jaydip Bhaliya, Gautam M. Patel

et al.

Journal of Inorganic and Organometallic Polymers and Materials, Journal Year: 2022, Volume and Issue: 32(3), P. 741 - 772

Published: Jan. 22, 2022

Language: Английский

Citations

43

Recent advancement in electrode materials and fabrication, microfluidic designs, and self-powered systems for wearable non-invasive electrochemical glucose monitoring DOI
Alireza Sanati, Yasaman Esmaeili,

Elham Bidram

et al.

Applied Materials Today, Journal Year: 2022, Volume and Issue: 26, P. 101350 - 101350

Published: Jan. 2, 2022

Language: Английский

Citations

41

Composite Nanoarchitectonics of Magnetic Silicon Dioxide-Modified Chitosan for Doxorubicin Delivery and In Vitro Cytotoxicity Assay DOI Creative Commons
Mostafa Y. Nassar,

Hamed I. El-Salhy,

W. H. El-Shiwiny

et al.

Journal of Inorganic and Organometallic Polymers and Materials, Journal Year: 2022, Volume and Issue: 33(1), P. 237 - 253

Published: Oct. 1, 2022

Abstract Developing drug delivery carriers for highly selective, controlled, and sustained release of the anti-cancer drugs is one crucial issues in cancer strive. We herein report synthesis Fe 3 O 4 (M) SiO 2 (S) nanoparticles their nanocomposites with chitosan (CS) high loading efficiency subsequent potentiality Doxorubicin (DOX) anticancer drug. The as-synthesized nanostructures were characterized using Fourier transform infrared (FT-IR), X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), high-resolution transmission (HR-TEM), thermal analysis techniques. average crystallite sizes as-prepared M, S, CS/M, CS/S, CS/M/S found to be 5, 15, 70, 22, 29 nm, respectively. cumulative produced examined, results exhibited efficacy 71%, 95%, 96%, 79%, 17%, 42% CS, nanostructures, releasing revealed a promising percentages at pH 4.2 5 compared those 7.4. At 4.2, DOX-M, DOX-S, DOX-CS, DOX/M, DOX/CS/M/S 94%, 92%, 98%, While corresponding 97%, 90%, 46%, 43%, 70%. percentage DOX-CS/S was 60% though. in-vitro cytotoxicity M-DOX, CS-DOX, M/CS-DOX explored against two human cell lines (MCF-7 Hep-G2) SRB (Sulforhodamine B) assay. DOX-loaded M/CS highest its IC 50 values 2.65 2.25 μg/mL Hep-G2 MCF-7 lines, respectively, 5.1 4.5 free DOX. indicated that nanocomposite good candidate as nano-carrier

Language: Английский

Citations

40

A Review of Biomimetic and Biodegradable Magnetic Scaffolds for Bone Tissue Engineering and Oncology DOI Open Access
Gheorghe Păltânea, Veronica Mănescu, Iulian Antoniac

et al.

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(5), P. 4312 - 4312

Published: Feb. 21, 2023

Bone defects characterized by limited regenerative properties are considered a priority in surgical practice, as they associated with reduced quality of life and high costs. In bone tissue engineering, different types scaffolds used. These implants represent structures well-established that play an important role delivery vectors or cellular systems for cells, growth factors, bioactive molecules, chemical compounds, drugs. The scaffold must provide microenvironment increased potential at the damage site. Magnetic nanoparticles linked to intrinsic magnetic field, when incorporated into biomimetic structures, can sustain osteoconduction, osteoinduction, angiogenesis. Some studies have shown combining ferromagnetic superparamagnetic external stimuli such electromagnetic field laser light enhance osteogenesis angiogenesis even lead cancer cell death. therapies based on vitro vivo could be included clinical trials large defect regeneration treatments near future. We highlight scaffolds' main attributes focus natural synthetic polymeric biomaterials combined their production methods. Then, we underline structural morphological aspects mechanical, thermal, properties. Great attention is devoted effects biocompatibility, osteogenic impact reinforced nanoparticles. explain biological processes activated due particles' presence possible toxic effects. present some regarding animal tests applications scaffolds.

Language: Английский

Citations

36

Functional Nanomaterials for the Diagnosis of Alzheimer's Disease: Recent Progress and Future Perspectives DOI Creative Commons
Saqer Al Abdullah, Lubna Najm, Liane Ladouceur

et al.

Advanced Functional Materials, Journal Year: 2023, Volume and Issue: 33(37)

Published: May 24, 2023

Alzheimer's disease (AD) is one of the main causes dementia worldwide, whereby neuronal death or malfunction leads to cognitive impairment in elderly population. AD highly prevalent, with increased projections over next few decades. Yet current diagnostic methods for occur only after presentation clinical symptoms. Evidence literature points potential mechanisms induction beginning before symptoms start present, such as formation amyloid beta (A

Language: Английский

Citations

27

Surface functionalized nanoparticles: A boon to biomedical science DOI
Kanchan Upadhyay, Raunak Kumar Tamrakar, Sabu Thomas

et al.

Chemico-Biological Interactions, Journal Year: 2023, Volume and Issue: 380, P. 110537 - 110537

Published: May 12, 2023

Language: Английский

Citations

25