Gels,
Journal Year:
2024,
Volume and Issue:
10(11), P. 689 - 689
Published: Oct. 24, 2024
Stimuli-responsive
nanocomposite
gels
combine
the
unique
properties
of
hydrogels
with
those
nanoparticles,
thus
avoiding
suboptimal
results
single
components
and
creating
versatile,
multi-functional
platforms
for
therapeutic
diagnostic
applications.
These
hybrid
materials
are
engineered
to
respond
various
internal
external
stimuli,
such
as
temperature,
pH,
light,
magnetic
fields,
enzymatic
activity,
allowing
precise
control
over
drug
release,
tissue
regeneration,
biosensing.
Their
responsiveness
environmental
cues
permits
personalized
medicine
approaches,
providing
dynamic
interventions
real-time
capabilities.
This
review
explores
recent
advances
in
stimuli-responsive
gels'
synthesis
application,
including
delivery,
engineering,
diagnostics.
Overall,
these
have
significant
clinical
potential,
future
research
is
expected
lead
solutions
address
unmet
medical
needs.
Materials Today Bio,
Journal Year:
2022,
Volume and Issue:
18, P. 100508 - 100508
Published: Nov. 30, 2022
Poor
wound
healing
after
diabetes
mellitus
remains
a
challenging
problem,
and
its
pathophysiological
mechanisms
have
not
yet
been
fully
elucidated.
Persistent
bleeding,
disturbed
regulation
of
inflammation,
blocked
cell
proliferation,
susceptible
infection
impaired
tissue
remodeling
are
the
main
features
diabetic
healing.
Conventional
dressings,
including
gauze,
films
bandages,
limited
function.
They
generally
act
as
physical
barriers
absorbers
exudates,
which
fail
to
meet
requirements
whol
process.
Wounds
in
patients
typically
heal
slowly
due
hyperglycemia
within
bed.
Once
bacterial
cells
develop
into
biofilms,
wounds
will
exhibit
robust
drug
resistance.
Recently,
application
stimuli-responsive
hydrogels,
also
known
"smart
hydrogels",
for
has
attracted
particular
attention.
The
basic
feature
this
system
is
capacities
change
mechanical
properties,
swelling
ability,
hydrophilicity,
permeability
biologically
active
molecules,
etc.,
response
various
stimuli,
temperature,
potential
hydrogen
(pH),
protease
other
biological
factors.
Smart
hydrogels
can
improve
therapeutic
efficacy
limit
total
toxicity
according
characteristics
wounds.
In
review,
we
summarized
mechanism
It
hoped
that
work
provide
some
inspiration
suggestions
research
field.
BMEMat,
Journal Year:
2023,
Volume and Issue:
1(2)
Published: April 15, 2023
Abstract
Due
to
global
aging
problems,
the
rising
number
of
patients
suffering
from
chronic
or
hard‐to‐heal
acute
wounds
imposes
a
significant
burden
on
healthcare
systems.
Wound
healing
is
complicated
and
dynamic
physiological
process
with
distinct
molecular
cellular
levels
at
each
phase.
Despite
numerous
strategies
advanced
wound
dressings
being
developed,
successful
management
through
smart
dressing
materials
that
can
adapt
changing
microenvironments
address
needs
different
stages
remains
big
challenge.
Over
last
decade,
hydrogel‐based
have
emerged
as
one
most
potent
biomaterials
for
treatment
favorable
biological
characteristics
high
potential
active
intervention
during
wound‐curing
process.
In
current
contribution,
we
present
recent
progress
in
hydrogel
regulate
release
therapeutics
response
external
stimuli
(such
light)
well
endogenous
changes
environments
(e.g.,
temperature,
pH,
glucose,
reactive
oxygen
species)
facilitate
healing.
We
also
introduce
cutting‐edge
technologies
intelligent
“sense‐and‐treat”
combination
built‐in
sensors
sensing
molecules
responsive
hydrogels,
which
enable
real‐time
monitoring
conditions
prompt
on‐demand
therapy.
ACS Nano,
Journal Year:
2023,
Volume and Issue:
17(9), P. 7953 - 7978
Published: April 18, 2023
Hydrogels,
as
one
of
the
most
feasible
soft
biomaterials,
have
gained
considerable
attention
in
therapeutic
applications
by
virtue
their
tunable
properties
including
superior
patient
compliance,
good
biocompatibility
and
biodegradation,
high
cargo-loading
efficiency.
However,
hydrogel
application
is
still
limited
some
challenges
like
inefficient
encapsulation,
easy
leakage
loaded
cargoes,
lack
controllability.
Recently,
nanoarchitecture-integrated
systems
were
found
to
be
therapeutics
with
optimized
properties,
extending
bioapplication.
In
this
review,
we
briefly
presented
category
hydrogels
according
synthetic
materials
further
discussed
advantages
Additionally,
various
nanoarchitecture
hybrid
biomedical
engineering
are
systematically
summarized,
cancer
therapy,
wound
healing,
cardiac
repair,
bone
regeneration,
diabetes
obesity
therapy.
Last,
current
challenges,
limitations,
future
perspectives
development
flexible
addressed.
Nano Materials Science,
Journal Year:
2023,
Volume and Issue:
6(2), P. 115 - 138
Published: Sept. 11, 2023
Energy
storage
and
conservation
are
receiving
increased
attention
due
to
rising
global
energy
demands.
Therefore,
the
development
of
materials
is
crucial.
Thermal
(TES)
systems
based
on
phase
change
(PCMs)
have
in
prominence
over
past
two
decades,
not
only
because
their
outstanding
heat
capacities
but
also
superior
thermal
regulation
capability.
However,
issues
such
as
leakage
low
conductivity
limit
applicability
a
variety
settings.
Carbon-based
graphene
its
derivatives
can
be
utilized
surmount
these
obstacles.
This
study
examines
recent
advancements
graphene-based
composites
(PCCs),
where
nanostructures
graphene,
oxide
(GO),
functionalized
graphene/GO,
aerogel
(GA)
incorporated
into
PCMs
substantially
enhance
shape
stability
that
could
translated
better
capacity,
durability,
temperature
response,
thus
boosting
attractiveness
for
TES
systems.
In
addition,
applications
PCCs
various
disciplines,
buildings,
solar
utilization,
battery
management,
discussed
summarized.
Molecular Systems Design & Engineering,
Journal Year:
2023,
Volume and Issue:
8(9), P. 1097 - 1129
Published: Jan. 1, 2023
Typical
examples
of
structural
switchable
functional
groups
triggered
by
photo-,
pH-,
thermal-,
force-,
CO
2
-
or
redox-stimuli
for
constructing
stimuli-responsive
polymers.
Chemistry - An Asian Journal,
Journal Year:
2022,
Volume and Issue:
17(18)
Published: July 22, 2022
The
recognition-directed
host-guest
interaction
is
recognized
as
a
valuable
tool
for
creating
supramolecular
polymers.
Functional
hydrogels
constructed
through
the
dynamic
and
reversible
complexation
are
endowed
with
great
many
appealing
features,
such
superior
self-healing,
injectability,
flexibility,
stimuli-responsiveness
biocompatibility,
which
crucial
biological
medicinal
applications.
With
numerous
topological
structures
combinations
established
previously,
recent
breakthroughs
in
this
area
mostly
focus
on
further
improvement
fine-tuning
of
various
properties
practical
utilizations.
current
contribution
provides
comprehensive
overview
latest
developments
hydrogels,
particular
emphasis
innovative
molecular-level
design
strategies
hydrogel
formation
methodologies
targeting
at
wide
range
active
biomedical
domains,
including
drug
delivery,
3D
printing,
wound
healing,
tissue
engineering,
artificial
actuators,
biosensors,
etc.
Furthermore,
brief
conclusion
discussion
steps
forward
to
bring
these
smart
clinical
practice
also
presented.
Chemistry - An Asian Journal,
Journal Year:
2022,
Volume and Issue:
18(2)
Published: Nov. 22, 2022
Polypropylene
(PP)
is
among
the
most
widely
used
commodity
plastics
in
our
everyday
life
due
to
its
low
cost,
lightweight,
easy
processability,
and
exceptional
chemical,
thermo-mechanical
characteristics.
The
growing
awareness
on
energy
environmental
crisis
has
driven
global
efforts
for
creating
a
circular
economy
via
developing
sustainable
eco-friendly
alternatives
traditional
produced
from
fossil
fuels
variety
of
end-use
applications.
This
review
paper
presents
brief
outline
emerging
bio-based
PP
derived
renewable
natural
resources,
covering
production
routes,
market
analysis
potential
utilizations.
contribution
also
provides
comprehensive
PP-based
biocomposites
with
diverse
green
fillers
generated
agro-industrial
wastes,
particular
emphasis
structural
modification,
processing
techniques,
mechanical
properties,
practical
Furthermore,
given
that
majority
products
are
currently
destined
landfills,
research
progress
enhancing
degradation
presented
light
concerns.
Finally,
conclusion
discussions
challenges
future
perspectives
provided.
