Nanotechnology Reviews,
Journal Year:
2024,
Volume and Issue:
13(1)
Published: Jan. 1, 2024
Abstract
Silver
nanoparticles
(AgNPs)
can
provide
excellent,
reliable,
and
effective
solutions
for
anti-microbial,
drug-loading,
other
purposes
due
to
their
extraordinary
physical,
chemical,
biological
characteristics.
Different
methods
have
been
used
in
the
synthesis
characterization
of
AgNPs,
AgNPs
applied
various
fields
biomedicine,
including
dentistry,
oncology,
diabetology,
neurodegenerative
disorders,
so
on.
However,
cytotoxicity
has
not
solved
during
application,
making
them
controversial.
The
aim
this
review
is
summarize
capabilities,
synthesis,
methods,
application
biomedicine
fields.
In
addition,
toxicity
explicated,
enhancing
benefit
properties
reducing
are
demonstrated.
end,
perspective
AgNPs’
research
proposed
great
potential
contributing
human
health.
Materials Today Bio,
Journal Year:
2023,
Volume and Issue:
19, P. 100586 - 100586
Published: Feb. 15, 2023
With
the
aging
of
population
and
rapid
improvement
public
health
medical
level
in
recent
years,
people
have
had
an
increasing
demand
for
orthopedic
implants.
However,
premature
implant
failure
postoperative
complications
frequently
occur
due
to
implant-related
infections,
which
not
only
increase
social
economic
burden,
but
also
greatly
affect
patient's
quality
life,
finally
restraining
clinical
use
Antibacterial
coatings,
as
effective
strategy
solve
above
problems,
been
extensively
studied
motivated
development
novel
strategies
optimize
implant.
In
this
paper,
a
variety
antibacterial
coatings
recently
developed
implants
were
briefly
reviewed,
with
focus
on
synergistic
multi-mechanism
multi-functional
smart
that
are
more
potential
use,
thereby
providing
theoretical
references
further
fabrication
high-performance
satisfying
complex
needs.
International Journal of Molecular Sciences,
Journal Year:
2022,
Volume and Issue:
23(23), P. 14987 - 14987
Published: Nov. 29, 2022
Guided
bone
regeneration
(GBR)
has
become
a
clinically
standard
modality
for
the
treatment
of
localized
jawbone
defects.
Barrier
membranes
play
an
important
role
in
this
process
by
preventing
soft
tissue
invasion
outgoing
from
mucosa
and
creating
underlying
space
to
support
growth.
Different
membrane
types
provide
different
biological
mechanisms
due
their
origins,
preparation
methods
structures.
Among
them,
collagen
have
attracted
great
interest
excellent
properties
desired
results
non-absorbable
even
without
second
surgery
removal.
This
work
provides
comparative
summary
common
barrier
used
GBR,
focusing
on
recent
advances
mechanisms.
In
conclusion,
review
article
highlights
regenerative
currently
available
with
particular
focus
bioresorbable
collagen-based
materials.
addition,
advantages
disadvantages
these
biomaterials
are
highlighted,
possible
improvements
future
material
developments
summarized.
Journal of Nanobiotechnology,
Journal Year:
2023,
Volume and Issue:
21(1)
Published: Aug. 26, 2023
Bacterial
infections,
especially
those
caused
by
drug-resistant
bacteria,
have
seriously
threatened
human
life
and
health.
There
is
urgent
to
develop
new
antibacterial
agents
reduce
the
problem
of
antibiotics.
Biomedical
materials
with
good
antimicrobial
properties
been
widely
used
in
applications.
Among
them,
hydrogels
become
focus
research
field
biomedical
due
their
unique
three-dimensional
network
structure,
high
hydrophilicity,
biocompatibility.
In
this
review,
latest
progresses
about
recent
years
were
summarized,
mainly
including
preparation
methods
According
different
mechanisms,
several
representative
introduced,
such
as
antibiotics
loaded
hydrogels,
antibiotic-free
metal-based
peptide
polymers,
stimuli-responsive
smart
light-mediated
hydrogels.
addition,
we
also
discussed
applications
challenges
biomedicine,
which
are
expected
provide
directions
ideas
for
application
clinical
therapy.
ACS Materials Letters,
Journal Year:
2023,
Volume and Issue:
5(12), P. 3142 - 3155
Published: Oct. 27, 2023
Antibacterial,
anti-inflammatory,
and
healing-promoting
treatment
of
chronically
infected
wounds
is
not
only
clinical
problems
to
be
solved
urgently
but
also
important
needs
related
people's
livelihood.
However,
multifunctional
hydrogel
dressings
with
highly
efficient
antibacterial,
wound
microenvironment
sensitive
drug
release
performance
still
remain
a
challenge.
In
this
work,
dressing
was
achieved
by
introducing
mussel-like
super
adhesion
catechol
groups
glucose/ROS-sensitive
dynamic
phenylboronester
bond
cross-linking
network,
which
endowed
the
excellent
injectable,
self-healing,
tissue
properties,
performance.
Additionally,
high-efficiency
photothermal
synergistic
antibacterial
TP@Ag
NPs
were
prepared
introduced
into
hydrogel.
The
glucose/ROS
responsive
borate
in
network
could
realize
NPs,
thereby
promoting
M2
polarization
achieve
an
anti-inflammatory
effect.
And
excess
reactive
oxygen
(ROS)
scavenged
effect
group
ROS-sensitive
Moreover,
biocompatibility
antioxidant
shown
hydrogels.
Finally,
fully
fill
adhere
irregular
through
injection
significantly
promote
diabetic
healing
vivo
sterilization,
ROS
scavenging
ability,
modulation
macrophage
reduce
inflammatory
response.
Thus,
it
illustrated
superiority
as
advanced
functional
for
healing.
Bioactive Materials,
Journal Year:
2022,
Volume and Issue:
21, P. 44 - 56
Published: Aug. 13, 2022
Implant-associated
infections
(IAIs)
caused
by
biofilm
formation
are
the
most
devastating
complications
of
orthopedic
surgery.
Statins
have
been
commonly
and
safely
used
drugs
for
hypercholesterolemia
many
years.
Here,
we
report
that
simvastatin-hydroxyapatite-coated
titanium
alloy
prevents
biofilm-associated
infections.
The
antibacterial
properties
simvastatin
against
Staphylococcus
aureus
epidermidis
biofilms
in
vitro
was
confirmed
crystal
violet
staining
live-dead
bacterial
staining.
We
developed
a
simvastatin-and
hydroxyapatite
(Sim-HA)-coated
via
electrochemical
deposition.
Sim-HA
coatings
inhibited
improved
biocompatibility
alloy.
effectively
prevented
IAI
rat
femurs,
as
radiological
assessment
histological
examination.
effects
were
attributed
to
their
inhibitory
on
formation,
verified
scanning
electron
microscopic
observations
spread
plate
analysis.
In
addition,
enhanced
osteogenesis
osteointegration,
micro-CT,
evaluation,
biomechanical
pull-out
tests.
summary,
promising
implant
materials
protection
Advanced Materials,
Journal Year:
2023,
Volume and Issue:
36(17)
Published: July 20, 2023
Abstract
The
discovery
of
antibiotics
has
saved
millions
lives,
but
the
emergence
antibiotic‐resistant
bacteria
become
another
problem
in
modern
medicine.
To
avoid
or
reduce
overuse
antibacterial
treatments,
stimuli‐responsive
materials,
pathogen‐targeting
nanoparticles,
immunogenic
nano‐toxoids,
and
biomimetic
materials
are
being
developed
to
make
sterilization
better
smarter
than
conventional
therapies.
common
goal
smart
(SAMs)
is
increase
antibiotic
efficacy
function
via
an
mechanism
different
from
that
order
biological
properties
while
reducing
risk
drug
resistance.
research
development
SAMs
increasingly
interdisciplinary
because
new
designs
require
knowledge
fields
input/collaboration
scientists
fields.
A
good
understanding
energy
conversion
physiological
characteristics
cells
bacteria,
bactericidal
structures
components
nature
expected
promote
SAMs.
In
this
review,
importance
multidisciplinary
insights
for
emphasized,
latest
advances
categorized
discussed
according
pertinent
disciplines
including
science,
physiology,
biomimicry.
