Hybrid Films Prepared from a Combination of Electrospinning and Casting for Offering a Dual-Phase Drug Release DOI Open Access
Haoran Liu,

Wenlai Jiang,

Zili Yang

et al.

Polymers, Journal Year: 2022, Volume and Issue: 14(11), P. 2132 - 2132

Published: May 24, 2022

One of the most important trends in developments electrospinning is to combine itself with traditional materials production and transformation methods take advantage unique properties nanofibers. In this research, single-fluid blending process was combined casting film method fabricate a medicated double-layer hybrid provide dual-phase drug controlled release profile, ibuprofen (IBU) as common model poorly water-soluble ethyl cellulose (EC) polyvinylpyrrolidone (PVP) K60 polymeric excipients. Electrospun IBU-PVP nanofibers (F7), IBU-EC films (F8) (DHFs, F9) one layer electrospun containing IBU PVP other IBU, EC PVP, were prepared successfully. The SEM assessments demonstrated that F7 linear morphologies without beads or spindles, F8 solid films, F9 composed porous fibrous layer. XRD FTIR results verified both compatible IBU. vitro dissolution tests indicated able pulsatile release, offered typical sustained whereas exhibit 40.3 ± 5.1% first phase for manner residues released an extended second phase. DHFs from combination pave new way developing novel functional materials.

Language: Английский

Recent Progress of Electrospun Herbal Medicine Nanofibers DOI Creative Commons
Hang Liu,

Yubin Bai,

Chang Huang

et al.

Biomolecules, Journal Year: 2023, Volume and Issue: 13(1), P. 184 - 184

Published: Jan. 16, 2023

Herbal medicine has a long history of medical efficacy with low toxicity, side effects and good biocompatibility. However, the bioavailability extract raw herbs bioactive compounds is poor because their water solubility. In order to overcome solubility issues, electrospinning technology can offer delivery alternative resolve them. The electrospun fibers have advantages high specific surface area, porosity, excellent mechanical strength flexible structures. At same time, various natural synthetic polymer-bound mimic extracellular matrix applications in different fields. this paper, development polymers used for incorporating herbal into nanofibers are reviewed. Finally, recent progress these biomedical (drug delivery, wound dressing, tissue engineering) food fields along future prospects discussed.

Language: Английский

Citations

59
Recent progress in electrospun nanofibers and their applications in heavy metal wastewater treatment DOI

Xizi Xu,

He Lv, Mingxin Zhang

et al.

Frontiers of Chemical Science and Engineering, Journal Year: 2023, Volume and Issue: 17(3), P. 249 - 275

Published: Jan. 3, 2023

Language: Английский

Citations

52
How can Electrospinning Further Service Well for Pharmaceutical Researches? DOI
Deng‐Guang Yu, Jianfeng Zhou

Journal of Pharmaceutical Sciences, Journal Year: 2023, Volume and Issue: 112(11), P. 2719 - 2723

Published: Aug. 27, 2023

Language: Английский

Citations

51
Alginate-Based Electrospun Nanofibers and the Enabled Drug Controlled Release Profiles: A Review DOI Creative Commons
Zhiyuan Zhang, Hui Liu, Deng‐Guang Yu

et al.

Biomolecules, Journal Year: 2024, Volume and Issue: 14(7), P. 789 - 789

Published: July 3, 2024

Alginate is a natural polymer with good biocompatible properties and potential polymeric material for the sustainable development replacement of petroleum derivatives. However, non-spinnability pure alginate solutions has hindered expansion applications. With continuous electrospinning technology, synthetic polymers, such as PEO PVA, are used co-spinning agents to increase spinnability alginate. Moreover, coaxial, parallel Janus, tertiary other diverse novel electrospun fiber structures prepared by multi-fluid have found new breakthrough problem poor spinning polymers. Meanwhile, effectively achieve multiple release modes drugs. The powerful combination electrostatic widely in many biomedical fields, tissue engineering, regenerative bioscaffolds, drug delivery, research fever continues climb. This particularly true controlled delivery aspect review provides brief overview alginate, introduces advances spinning, highlights progress alginate-based nanofibers achieving various modes, pulsed release, sustained biphasic responsive targeted release.

Language: Английский

Citations

50
Recent Combinations of Electrospinning with Photocatalytic Technology for Treating Polluted Water DOI Open Access
He Lv, Yanan Liu,

Yubin Bai

et al.

Catalysts, Journal Year: 2023, Volume and Issue: 13(4), P. 758 - 758

Published: April 15, 2023

Dyes, antibiotics, heavy metal ions, and bacteria are important sources of water pollution. How to solve these issues has become a problem in the fields science technology. People have developed variety technologies treat pollutants water. Photocatalytic technology came into being. As simple environmentally friendly treatment technology, it been widely studied by scientific community. Traditional powder photocatalysts cause secondary pollution environment not conducive recycling. Therefore, large specific surface area reusable membrane built electrospinning favorite today’s Nanofiber membranes prepared structures, which can meet needs different occasions. This review summarizes discusses research progress relationship between structure electrospun fiber membranes, their impacts on photocatalytic performance nanofiber membranes. The performance, challenges, future development directions with kinds techniques using photocatalysis pollutants, reviewed.

Language: Английский

Citations

46
Engineered protein-based materials for tissue repair: A review DOI
Jiayin Feng, Fangyan Wang,

Yunyuan Shao

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 303, P. 140674 - 140674

Published: Feb. 3, 2025

Language: Английский

Citations

6
One-Step Side-by-Side Electrospraying of Janus Particles for Durable Multifunctional Coatings on Cotton Textiles DOI
Chen Shu,

Xiongying Wu,

Xuemei Ding

et al.

Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2025, Volume and Issue: unknown, P. 136227 - 136227

Published: Jan. 1, 2025

Language: Английский

Citations

5
Advances in the Preparation of Nanofiber Dressings by Electrospinning for Promoting Diabetic Wound Healing DOI Creative Commons
Yukang Liu, Chaofei Li, Zhangbin Feng

et al.

Biomolecules, Journal Year: 2022, Volume and Issue: 12(12), P. 1727 - 1727

Published: Nov. 22, 2022

Chronic diabetic wounds are one of the main complications diabetes, manifested by persistent inflammation, decreased epithelialization motility, and impaired wound healing. This will not only lead to repeated hospitalization patients, but also bear expensive costs. In severe cases, it can amputation, sepsis or death. Electrospun nanofibers membranes have characteristics high porosity, specific surface area, easy functionalization structure, so they be used as a safe effective platform in treatment great application potential. article briefly reviewed pathogenesis chronic types dressings commonly used, then development electrospinning technology recent years advantages electrospun wounds. Finally, reports different nanofiber on summarized, method using multi-drug combination therapy is emphasized, which provides new ideas for

Language: Английский

Citations

64
A Review on Electrospun Poly(amino acid) Nanofibers and Their Applications of Hemostasis and Wound Healing DOI Creative Commons

Yuexin Ji,

Wenliang Song, Lin Xu

et al.

Biomolecules, Journal Year: 2022, Volume and Issue: 12(6), P. 794 - 794

Published: June 7, 2022

The timely and effective control repair of wound bleeding is a key research issue all over the world. From traditional compression hemostasis to variety new hemostatic methods, people have more comprehensive understanding mechanism structure function different types dressings. Electrospun nanofibers stand out with nano size, high specific surface area, higher porosity, complex structures. They are high-quality materials that can effectively promote healing because they imitate structural characteristics skin extracellular matrix (ECM) support cell adhesion angiogenesis. At same time, combined amino acid polymers good biocompatibility not only has compatibility human body but also be drugs further improve effect dressing. This paper summarizes application electrospun dressings, analyzes in preparation application, looks forward development directions poly(amino acid) dressings hemostasis.

Language: Английский

Citations

60
The Key Elements for Biomolecules to Biomaterials and to Bioapplications DOI Creative Commons
Deng‐Guang Yu, Ping Zhao

Biomolecules, Journal Year: 2022, Volume and Issue: 12(9), P. 1234 - 1234

Published: Sept. 4, 2022

Biomolecules, as molecules which have a bio-source or certain bioapplication, are at present quickening the marching speed for benefiting people's life and social progress [...].

Language: Английский

Citations

60