Klasifikasi Jamur Menggunakan Algoritma Naïve Bayes DOI Open Access
Regiolina Hayami,

Soni Soni,

I Kadek Wahyu Adi Gunawan

et al.

Jurnal CoSciTech (Computer Science and Information Technology), Journal Year: 2022, Volume and Issue: 3(1), P. 28 - 33

Published: May 31, 2022

Jamur merupakan tanaman dari kingdom fungi dengan tubuh berdaging dan dapat dimakan, meski demikian terdapat beberapa spesies jamur yang tidak dimakan memiliki ciri khas tersendiri. Banyaknya orang mengkomsumsi tanpa tahu apakah dikomsumsi aman untuk atau beracun mengakibatkan banyak insiden keracunan bahkan hingga meninggal. Salah satu jenis edukasi dilakukan adalah membuat sebuah alat dalam bentuk perangkat lunak mengklasifikasikan menjadi bisa beracun. klasifikasi menggunakan algoritma kecerdasan buatan Naïve Bayes mengasumsikan setiap nilai atribut mempengaruhi kelas bersifat independen lainnya. Data digunakan diperoleh berupa dataset berisi kriteria UCI Machine Learning Repository telah dilabelkan kedalam edible poisionous total data sebanyak 8124 data. Dataset akan dibagi dua masing-masing train test porsi 80% banding 20% 90% 10%. Klasifikasi empat kali pembagian categorical naïve bayes multinomial sehingga dihasilkan 4(empat) model klasifikasi. Berdasarkan hasil evaluasi confusion matrix dilihat bahwa terbaik jarak performa cukup besar dimana Categorical1 Categorical2 mendapatkan akurasi 100% 1 kesalahan prediksi 0 pada Categorical 2. Sementara itu, Multinomial1 Multinomial2 sebesar 84% 85%.

Mushrooms as future generation healthy foods DOI Creative Commons
Victoria Bell,

Cídia Rosália Pinho Guina Silva,

José Guina

et al.

Frontiers in Nutrition, Journal Year: 2022, Volume and Issue: 9

Published: Dec. 6, 2022

The potential of edible mushrooms as an unexploited treasure trove, although rarely included in known food guidelines, is highlighted. Their role shielding people against the side effects unhealthy stylish diet reviewed. Mushrooms complement human with various bioactive molecules not identified or deficient foodstuffs plant and animal sources, being considered a functional for prevention several diseases. have been widely used medicinal products more than 2,000 years, but globally field use wild has untapped. There broad range which remain poorly even unreported valuable pool sources compounds biopharma utilization new dietary supplements. Some unique elements their preventative healthcare are emphasized, through positive impact on immune system. antiviral, anti-inflammatory, anti-neoplastic, other health concerns discussed. incorporate top non-digestible oligosaccharides, ergothioneine, humans unable to synthesize, later antioxidant, cytoprotective, anti-inflammatory element, therapeutic potential, approved by world agencies. prebiotic activity beneficially affects gut homeostasis performance balance microbiota enhanced. Several recent studies neurological contribution growth nerve brain cells mentioned. Indeed, foods' nutraceuticals presently regarded next-generation foods, supporting wellness, promising prophylactic agents.

Language: Английский

Citations

88
An insight into the nutritional and medicinal value of edible mushrooms: A natural treasury for human health DOI

Arman Hamza,

Ankit Mylarapu,

K. V. Radha Krishna

et al.

Journal of Biotechnology, Journal Year: 2024, Volume and Issue: 381, P. 86 - 99

Published: Jan. 3, 2024

Language: Английский

Citations

32
Current Uses of Mushrooms in Cancer Treatment and Their Anticancer Mechanisms DOI Open Access

Hye-Jin Park

International Journal of Molecular Sciences, Journal Year: 2022, Volume and Issue: 23(18), P. 10502 - 10502

Published: Sept. 10, 2022

Cancer is the leading cause of mortality worldwide. Various chemotherapeutic drugs have been extensively used for cancer treatment. However, current anticancer severe side effects and induce resistance. Therefore, development novel effective agents with minimal or no important. Notably, natural compounds highlighted as drugs. Among them, many researchers focused on mushrooms that biological activities, including antitumor activity. The aim this review to discuss potential different underlying molecular mechanisms. We provide information regarding clinical status possible modes actions various mushroom-derived compounds. This will help clinicians in designing evidence-based preclinical studies test their active types cancers.

Language: Английский

Citations

50
Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer DOI Open Access
Marzia Bruna Gariboldi, Emanuela Marras, N. Ferrario

et al.

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(12), P. 10120 - 10120

Published: June 14, 2023

Edible/medicinal mushrooms have been traditionally used in Asian countries either the cuisine or as dietary supplements and nutraceuticals. In recent decades, they aroused increasing attention Europe well, due to their health nutritional benefits. particular, among different pharmacological activities reported (antibacterial, anti-inflammatory, antioxidative, antiviral, immunomodulating, antidiabetic, etc.), edible/medicinal shown exert vitro vivo anticancer effects on several kinds of tumors, including breast cancer. this article, we reviewed showing antineoplastic activity again cancer cells, especially focusing possible bioactive compounds involved mechanisms action. following considered: Agaricus bisporus, Antrodia cinnamomea, Cordyceps sinensis, militaris, Coriolus versicolor, Ganoderma lucidum, Grifola frondosa, Lentinula edodes, Pleurotus ostreatus. We also report insights into relationship between consumption edible risk, results clinical studies meta-analyses fungal extracts patients.

Language: Английский

Citations

23
Exploring the therapeutic properties of chinese mushrooms with a focus on their anti-cancer effects: A systemic review DOI Creative Commons
Priyanka Ray,

Shreya Kundu,

Diptayan Paul

et al.

Pharmacological Research - Modern Chinese Medicine, Journal Year: 2024, Volume and Issue: 11, P. 100433 - 100433

Published: April 21, 2024

Mushrooms have long been integral components of traditional Chinese medicine (TCM), contributing significantly to the holistic approach health and well-being. This review presents a critical study on mushrooms' role in Traditional Medicine emphasizing their potent anticancer properties. pivotal TCM for centuries, healing practices. The article aims comprehensively explore historical significance, therapeutic properties, scientific validation within framework TCM, particularly efficacy cancer prevention treatment. A thorough search was made through electronic sources like Scopus, PubMed, ResearchGate, Elsevier Journals find studies "Medicinal mushrooms fungus," "cancer," "tumour," "traditional medicine," "antioxidant." Only entire English-language articles were used. analysis excluded that did not fit requirements. examined mushroom species antioxidant, anticancer, tumor suppressive, antibacterial lists many names. Figure 1 depicts method flow chart form. Ganoderma lucidum (Reishi) targets PI3K/AKT/mTOR pathway, crucial cell survival. Trametes versicolor, containing PSK or PSP, inhibits TNF-α-induced MMP-3 synthesis T98G glioma cells. Lignosus rhinoceros, after 24-hour LPS stimulation, COX-2 activity, demonstrating effective vivo anti-tumour potential. Cordyceps boosts immunological responses reduces microenvironment immunosuppression. Fomitopsis fomentarius intracellular polysaccharides suppress SGC 7091 gastric proliferation, while extracellular enhance immune mice. pinicola vascular endothelial growth factor may curb oxidative stress inflammation promoting cancer. Hericium erinaceus extracts inhibit breast proliferation vitro SCID Lentinan from Lentinula edodes suppresses alters gene expression. Piptoporus betulinus adhesion induces apoptosis. Polyporus spp. induce apoptosis reduce growth. Tumulosic acid Poria cocos PI3K-Akt signaling ovarian Coriolus versicolor has immunomodulatory effects, suppressing TNF-α enhancing IFN-β levels, reducing invasiveness directly indirectly. diverse activities various compounds are evident. These include modulating PI3K/AKT/mTOR, inducing apoptosis, angiogenesis, immunity progression. findings suggest potential as alternative supplementary therapies, necessitating further research understanding mechanisms, optimizing dosages, evaluating clinical safety, including exploring synergies with conventional treatments.

Language: Английский

Citations

11
Research progress on structural characterization and bioactivities of Poria cocos and Ganoderma polysaccharides DOI

Yikun Xie,

Xinyu Pan,

Xin-Ran Liang

et al.

Food & medicine homology., Journal Year: 2024, Volume and Issue: 2(1), P. 9420040 - 9420040

Published: Sept. 18, 2024

Language: Английский

Citations

6
Water-Insoluble Polysaccharide Extracted from Poria cocos Alleviates Antibiotic-Associated Diarrhea Based on Regulating the Gut Microbiota in Mice DOI Creative Commons

Yong Lai,

Huiling Deng,

Qi Fang

et al.

Foods, Journal Year: 2023, Volume and Issue: 12(16), P. 3080 - 3080

Published: Aug. 16, 2023

Antibiotics are very effective in treating a variety of bacterial infections, while clinical overuse antibiotics can lead to diseases such as antibiotic-associated diarrhea. Numerous studies have shown that natural polysaccharides be used prebiotics alleviate diarrhea (AAD). Poria cocos is medicinal and edible mushroom widely for thousands years China, our former study demonstrated water-insoluble polysaccharide (PCY) has the potential prebiotic function. Therefore, we simulated digestion fermentation PCY using feces from volunteers, then administered it C57BL/6 mice with AAD its effects on gut microbiota metabolites. The results indicated effectively alleviated symptoms mice, restored intestinal barrier function, improved content short-chain fatty acids (SCFAs), decreased level inflammatory cytokines, changed structure by increasing relative abundance norank_f__Muribaculaceae unclassified_f__Lachnospiraceae, decreasing Escherichia-Shigella, Staphylococcus Acinetobacter. This further an functional improving disease, provided new avenue insight developing food or alleviating gastrointestinal diseases.

Language: Английский

Citations

13
Antidiabetic and antioxidant potentials of Pleurotus ostreatus -derived compounds: An in vitro and in silico approach DOI Creative Commons

Stephen Chukwubuikem Nnemolisa,

Chukwudumebi Chukwurah,

S.C. Edeh

et al.

Food Chemistry Advances, Journal Year: 2024, Volume and Issue: 4, P. 100639 - 100639

Published: Feb. 10, 2024

Many health benefits have reportedly been associated with mushroom consumption. This study determined the chemical constituents of Pleurotus ostreatus methanol extract (MEPO) and investigated its antioxidant antidiabetic effects using in vitro silico approaches. The composition MEPO was gas chromatography-flame ionization detector (GC-FID) technique, while 2,2-Diphenyl-1-picrylhydrazyl (DPPH) ferric reducing power (FRAP) methods were used to determine activity. activity evaluated α-amylase α-glucosidase inhibition assays, molecular docking done give insight into binding potentials against α-amylase, α-glucosidase, phosphoenolpyruvate (PEP) carboxykinase activities. Thirteen compounds, including ephedrine, oxalate, rutin, naringin, kaempferol, identified MEPO. showed moderate activity, as observed from DPPH (IC50 = 732.41 mg/ml) FRAP studies. also demonstrated stronger 246.58 than 1074.05 mg/ml). Docking studies revealed that rutin naringin interacted effectively amino acid residues crucial for PEP activities via hydrogen bonds. result shows is a rich store beneficial compounds which could be explored management diabetes complications.

Language: Английский

Citations

4
Chemical structure characterization of edible mushroom-extracted beta-glucan and its bioactivity DOI
Ryan Haryo Setyawan, Ardi Ardiansyah, Nissa Nurfajrin Solihat

et al.

Bioactive Carbohydrates and Dietary Fibre, Journal Year: 2024, Volume and Issue: 31, P. 100411 - 100411

Published: Feb. 23, 2024

Language: Английский

Citations

4
The Potential of Mushroom Extracts to Improve Chemotherapy Efficacy in Cancer Cells: A Systematic Review DOI Creative Commons

Jéssica Fonsêca,

Josiana A. Vaz, Sara Ricardo

et al.

Cells, Journal Year: 2024, Volume and Issue: 13(6), P. 510 - 510

Published: March 14, 2024

Chemoresistance is a challenge in cancer treatment, limiting the effectiveness of chemotherapy. Mushroom extracts have shown potential as treatments for therapies, offering possible solution to overcome chemoresistance. This systematic review aimed explore role mushroom enhancing chemotherapy and reversing chemoresistance cells. We searched PubMed, Web Science Scopus databases, following PRISMA guidelines, registered on PROSPERO. The acted by inhibiting proliferation cells, well effect mechanisms which they included regulating anti-apoptotic proteins, JAK2/STAT3 pathway, ERK1/2 modulating microRNAs p-glycoprotein. These results highlight modulate multiple order improve efficacy work sheds light use an aid combat Although studies are limited, diversity mushrooms their bioactive compounds show promising innovative strategies treat more effectively. It crucial carry out further better understand therapeutic

Language: Английский

Citations

4