Food Chemistry, Journal Year: 2023, Volume and Issue: 429, P. 136822 - 136822
Published: July 8, 2023
Language: Английский
Food Chemistry, Journal Year: 2023, Volume and Issue: 429, P. 136822 - 136822
Published: July 8, 2023
Language: Английский
Advanced Materials, Journal Year: 2021, Volume and Issue: 33(30)
Published: June 18, 2021
Abstract Advances in revolutionary technologies pose new challenges for human life; response to them, global responsibility is pushing modern toward greener pathways. Molecular imprinting technology (MIT) a multidisciplinary mimic simulating the specific binding principle of enzymes substrates or antigens antibodies; along with its rapid progress and wide applications, MIT faces challenge complying green sustainable development requirements. With identification environmental risks associated unsustainable MIT, aspect termed has emerged developed. However, so far, no clear definition been provided appraise MIT. Herein, implementation process chemistry demonstrated mnemonic device form an acronym, GREENIFICATION, proposed present principles. The entire greenificated surveyed, including element choice, polymerization implementation, energy input, strategies, waste treatment, recovery, as well impacts these processes on operator health environment. Moreover, assistance upgraded instrumentation deploying goals considered. Finally, future perspectives are presented provide more complete picture road map pave way further development.
Language: Английский
Citations
580Advanced Materials, Journal Year: 2022, Volume and Issue: 34(42)
Published: June 23, 2022
Abstract Molecular imprinting technology (MIT) produces artificial binding sites with precise complementarity to substrates and thereby is capable of exquisite molecular recognition. Over five decades evolution, it predicted that the resulting host imprinted materials will overtake natural receptors for research application purposes, but in practice, this has not yet been realized due unsustainability their life cycles (i.e., precursors, creation, use, recycling, end‐of‐life). To address issue, greenificated molecularly polymers (GMIPs) are a new class plastic antibodies have approached sustainability by following one or more greenification principles, while also demonstrating far‐reaching applications compared counterparts. In review, most recent developments delicate design advanced GMIPs six fast‐growing emerging fields surveyed, namely biomedicine/therapy, catalysis, energy harvesting/storage, nanoparticle detection, gas sensing/adsorption, environmental remediation. addition, distinct features highlighted, optimal means utilize these attaining incredibly discussed. Importantly, obscure technical challenges MIT revealed, conceivable solutions offered. Lastly, several perspectives on future directions proposed.
Language: Английский
Citations
285Nature Communications, Journal Year: 2022, Volume and Issue: 13(1)
Published: Sept. 30, 2022
Abstract Chiral discrimination is critical in environmental and life sciences. However, an ideal chiral strategy has not yet been developed because of the inevitable nonspecific binding entity wrong enantiomers or insufficient intrinsic optical activities molecules. Here, we propose “inspector” recognition mechanism (IRM), which implemented on a imprinted polydopamine (PDA) layer coated surface-enhanced Raman scattering (SERS) tag layer. The IRM works based permeability change PDA after scrutiny by inspector molecule. Good enantiomer can specifically recognize fully fill cavities, whereas cannot. Then linear shape aminothiol molecule, as status introduced, only percolate through vacant nonspecifically occupied inducing SERS signal to decrease. Accordingly, chirality information exclusively stems from good specific binding, while curbed. benefits sensitivity versatility, enabling absolute wide variety molecules regardless size, functional groups, polarities, activities, scattering, number centers.
Language: Английский
Citations
257Langmuir, Journal Year: 2022, Volume and Issue: 38(19), P. 5963 - 5967
Published: May 5, 2022
Combating environmental pollution constantly requires new affinity tools to selectively recognize and sensitively detect them. Molecularly imprinted polymers (MIPs) are plastic antibodies that have exhibited great potential as recognition units in optical sensing platforms monitor wide varieties of pollutants, including ionic species, organic compounds, gases, even manufactured nanoparticles. The construction, strategies, applications molecular-imprinting-based sensors (MI-OSs) been discussed recent reviews, thus we deliberately set them aside. This Perspective elaborates on unanswered questions main approaches being taken address the challenges MI-OS technologies, which less considered until now. Specifically, highlight obscure technical aspects fabrication validation impact their practical importantly offer conceivable solutions related problems bridge research gap.
Language: Английский
Citations
125Microchemical Journal, Journal Year: 2021, Volume and Issue: 170, P. 106685 - 106685
Published: July 27, 2021
Language: Английский
Citations
120Exploration, Journal Year: 2023, Volume and Issue: 3(1)
Published: Feb. 1, 2023
The methodological advancements in surface-enhanced Raman scattering (SERS) technique with nanoscale materials based on noble metals, Au, Ag, and their bimetallic alloy Au-Ag, has enabled the highly efficient sensing of chemical biological molecules at very low concentration values. By employing innovative various type Ag nanoparticles especially, high efficiency Au@Ag nanomaterials as substrate SERS biosensors have revolutionized detection components including; proteins, antigens antibodies complex, circulating tumor cells, DNA, RNA (miRNA), etc. This review is about SERS-based Au/Ag enhanced activity by focusing different factors related to them. emphasis this research describe recent developments field conceptual behind Furthermore, article we apex understanding impact variation basic features like effects size, shape varying lengths, thickness core-shell influence large-scale magnitude morphology. Moreover, detailed information applications these importantly receptor binding domain (RBD) protein COVID-19 provided.
Language: Английский
Citations
85Bioactive Materials, Journal Year: 2023, Volume and Issue: 34, P. 248 - 268
Published: Dec. 31, 2023
These days, cancer is thought to be more than just one illness, with several complex subtypes that require different screening approaches. can distinguished by the distinct markings left metabolites, proteins, miRNA, and DNA. Personalized illness management may possible if categorized according its biomarkers. In order stop from spreading posing a significant risk patient survival, early detection prompt treatment are essential. Traditional techniques tedious, time-consuming, expert personnel for analysis. This has led scientists reevaluate methodologies make use of emerging technologies achieve better results. Using time money saving techniques, these integrate procedures sample preparation in small devices high accuracy sensitivity. With proven potential biomedical use, surface-enhanced Raman scattering (SERS) been widely used biosensing applications, particularly biomarker identification. Consideration was given especially SERS as portable clinical diagnostic tool. The approaches SERS-based sensing both invasive non-invasive samples reviewed this article, along obstacles. Aside constraints approach review also takes into account complexity biological fluids, availability biomarkers, their sensitivity selectivity, which generally lowered. Massive ways maintain capabilities being developed recently get over restriction. known reliable method judgments. Nonetheless, there still room advancement terms portability, creation apps, interdisciplinary AI-based applications. Therefore, we will outline current state technological maturity article. meet demand reviewing various types (invasive non-invasive) biomarkers using SERS. It shed light on growing body research methods application quick detection.
Language: Английский
Citations
63Food Chemistry, Journal Year: 2023, Volume and Issue: 412, P. 135563 - 135563
Published: Jan. 27, 2023
Language: Английский
Citations
43Analytical Chemistry, Journal Year: 2024, Volume and Issue: 96(16), P. 6417 - 6425
Published: April 12, 2024
Molecular imprinting-based surface-enhanced Raman scattering (MI-SERS) sensors have shown remarkable potential from an academic standpoint. However, their practical applications, especially in the detection of large-size protein (≥10 nm), face challenges due to lack versatile sensing strategies and nonspecific fouling matrix species. Herein, we propose a reporter inspector mechanism (RRIM) implemented on protein-imprinted polydopamine (PDA) layer coated SERS active substrate. In RRIM, after recognition, permeability PDA imprinted cavities undergoes changes that are scrutinized by molecules. Target proteins can specifically bind fully occupy cavities, whereas species cannot. Then, molecules with suitable size introduced serve as both inspectors recognition status inducers signal, which only penetrate through vacant nonspecifically filled cavities. Consequently, signal exclusively originate specific binding target proteins, while is curbed. The RRIM enables reproducible quantitation cyanobacteria-specific model phycocyanin, at level down 2.6 × 10
Language: Английский
Citations
35TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 178, P. 117830 - 117830
Published: June 24, 2024
Language: Английский
Citations
21