Hyaluronic acid based approaches for wound healing: A comprehensive review DOI

Samay Parmal,

Praveen Subbappa,

Vaidehi Nikam

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141625 - 141625

Published: March 1, 2025

Language: Английский

Applications of Green Synthesized Metal Nanoparticles — a Review DOI Open Access
Seerengaraj Vijayaram, Hary Razafindralambo, Yun‐Zhang Sun

et al.

Biological Trace Element Research, Journal Year: 2023, Volume and Issue: 202(1), P. 360 - 386

Published: April 13, 2023

Language: Английский

Citations

265

Zinc Oxide Nanoparticles: Synthesis, Characterization, Modification, and Applications in Food and Agriculture DOI Open Access
Xianqing Zhou,

Zakir Hayat,

Dongdong Zhang

et al.

Processes, Journal Year: 2023, Volume and Issue: 11(4), P. 1193 - 1193

Published: April 13, 2023

Zinc oxide nanoparticles (ZnO-NPs) have gained significant interest in the agricultural and food industry as a means of killing or reducing activity microorganisms. The antibacterial properties ZnO-NPs may improve quality, which has direct impact on human health. are one most investigated inorganic been used various related sectors, with potential to rapidly gain attention increase agriculture industries. In this review, we describe methods for preparing ZnO-NPs, their characterizations, modifications, applications, antimicrobial activity, testing procedures, effects, including bactericidal bacteriostatic mechanisms. It is hoped that review could provide better understanding preparation application ZnO field agriculture, promote development advance agriculture.

Language: Английский

Citations

150

Current Overview of Metal Nanoparticles’ Synthesis, Characterization, and Biomedical Applications, with a Focus on Silver and Gold Nanoparticles DOI Creative Commons
Ana Flavia Burlec, Andreia Corciovă, Monica Boev

et al.

Pharmaceuticals, Journal Year: 2023, Volume and Issue: 16(10), P. 1410 - 1410

Published: Oct. 4, 2023

Metal nanoparticles (NPs) have garnered considerable attention, due to their unique physicochemical properties, that render them promising candidates for various applications in medicine and industry. This article offers a comprehensive overview of the most recent advancements manufacturing, characterization, biomedical utilization metal NPs, with primary focus on silver gold NPs. Their potential as effective anticancer, anti-inflammatory, antimicrobial agents, drug delivery systems, imaging agents diagnosis treatment variety disorders is reviewed. Moreover, translation therapeutic settings, issue inclusion clinical trials, are assessed light over 30 investigations concentrate administering either or NPs conditions ranging from nosocomial infections different types cancers. paper aims not only examine biocompatibility nanomaterials but also emphasize challenges may limit safe integration into healthcare practices. More than 100 nanomedicines currently market, which justifies ongoing study use medicine. Overall, present review highlight innovative therapeutics field biomedicine, citing some relevant current applications.

Language: Английский

Citations

88

Nanomaterials for wound healing: Current status and futuristic frontier DOI Creative Commons

J. Nandhini,

Karthikeyan Elumalai, S. Rajeshkumar

et al.

Biomedical Technology, Journal Year: 2023, Volume and Issue: 6, P. 26 - 45

Published: Nov. 8, 2023

Wound healing is a complex process that involves variety of physical, chemical, and biological processes. Because their remarkable characteristics capabilities, nanomaterials have recently emerged as potential therapeutic agents for wound healing. Many different nanomaterial-based wound-healing treatments been created put into widespread use. In this review, we compile the most recent research on cutting-edge healing, including both organic inorganic nanomaterials. We highlight prospective approaches developing therapy procedures talk about benefits limitations these treatments. Future prospects therapies based are discussed, need to address toxicity concerns, scalability production, long-term stability The safety effectiveness depend further investigation design, interactions with systems, results rigorous preclinical clinical trials. There great dramatic improvement in patient outcomes introduction therapies.

Language: Английский

Citations

85

Mycosynthesis of Hematite (α-Fe2O3) Nanoparticles Using Aspergillus niger and Their Antimicrobial and Photocatalytic Activities DOI Creative Commons
Ebrahim Saied, Salem S. Salem, Abdulaziz A. Al–Askar

et al.

Bioengineering, Journal Year: 2022, Volume and Issue: 9(8), P. 397 - 397

Published: Aug. 17, 2022

Nanoparticles (NPs) and nanomaterials (NMs) are now widely used in a variety of applications, including medicine, solar energy, drug delivery, water treatment, pollution detection. Hematite (α-Fe2O3) nanoparticles (Hem-NPs) were manufactured this work by utilizing cost-effective ecofriendly approach that included biomass filtrate A. niger AH1 as bio-reducer. The structural optical properties Hem-NPs investigated using X-ray diffraction (XRD), transmission electron microscopy (TEM), dynamic light scattering (DLS), UV-visible Fourier-transform infrared (FTIR) spectroscopies. results revealed all the studied parameters, well their interactions, had significant impact on crystallite size. average diameter size biosynthesized ranged between 60 80 nm. antimicrobial photocatalytic activities investigated. exhibited antibacterial activity against E. coli, B. subtilis, S. mutans with MICs 125, 31.25, 15.62 µg/mL, respectively. Moreover, antifungal C. albicans fumigatus, where 2000 62.5 efficiency was determined for rapid biodegradation crystal violet (CV) dye, reaching up to 97 percent after 150 min. Furthermore, successfully more than once regarded its efficacy. In conclusion, demonstrated both CV dye.

Language: Английский

Citations

70

Innovative nanomaterials for cancer diagnosis, imaging, and therapy: Drug delivery applications DOI
Mehrab Pourmadadi,

Mohammad Mahdi Eshaghi,

Shima Ostovar

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2023, Volume and Issue: 82, P. 104357 - 104357

Published: March 12, 2023

Language: Английский

Citations

49

Green Synthesis of Silver Nanoparticles Using Salvia verticillata and Filipendula ulmaria Extracts: Optimization of Synthesis, Biological Activities, and Catalytic Properties DOI Creative Commons
Vladimir Mihailović, Nikola Srećković,

Zoran Nedić

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(2), P. 808 - 808

Published: Jan. 13, 2023

The study's objective was to obtain silver nanoparticles (SVAgNP and FUAgNP) using aqueous extracts of Salvia verticillata Filipendula ulmaria. optimal conditions for nanoparticle synthesis were determined obtained; then characterized UV-Vis, Fourier-transform infrared spectroscopy (FTIR), X-ray powder diffraction (XRD), Dynamic Light Scattering (DLS), Scanning Electron Microscopy with Energy Dispersive Spectroscopy (SEM/EDS). SVAgNP FUAgNP possessed a crystalline structure 48.42% 60.41% weight, respectively. highest percentage in the solution had diameter between 40 70 nm. In DPPH˙ ABTS˙+ methods, (IC50 15.82 59.85 µg/mL, respectively) demonstrated higher antioxidant capacity than 73.47 79.49 respectively). Obtained also showed pronounced antibacterial activity (MIC ˂ 39.1 µg/mL most tested bacteria), as well high biocompatibility human fibroblast cell line MRC-5 significant cytotoxicity on some cancer lines, especially colon HCT-116 cells 31.50 66.51 FUAgNP, catalytic effectiveness degrading Congo red dye NaBH4. results rapid low-cost methodology AgNPs S. F. ulmaria promising biological potential.

Language: Английский

Citations

47

Plant-mediated synthesis of silver nanoparticles: unlocking their pharmacological potential–a comprehensive review DOI Creative Commons

Rajan Dhir,

Sakshi Chauhan,

Praddiuman Subham

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2024, Volume and Issue: 11

Published: Jan. 9, 2024

In recent times, nanoparticles have experienced a significant upsurge in popularity, primarily owing to their minute size and remarkable ability modify physical, chemical, biological properties. This burgeoning interest can be attributed the expanding array of biomedical applications where find utility. These nanoparticles, typically ranging from 10 100 nm, exhibit diverse shapes, such as spherical, discoidal, cylindrical configurations. variations are not solely influenced by manufacturing processes but also intricately linked interactions with surrounding stabilizing agents initiators. Nanoparticles synthesized through physical or chemical methods, yet approach emerges most sustainable eco-friendly alternative among three. Among various nanoparticle types, silver emerged encountered widely utilized due exceptional What makes synthesis even more appealing is application plant-derived sources reducing agents. only proves cost-effective significantly reduces time. Notably, produced plant-mediated garnered considerable attention years notable medicinal capabilities. comprehensive review delves into attributes using techniques. Encompassing antimicrobial properties, cytotoxicity, wound healing, larvicidal effects, anti-angiogenesis activity, antioxidant potential, antiplasmodial paper extensively covers these multifaceted roles. Additionally, an endeavor made provide elucidated summary operational mechanisms underlying pharmacological actions nanoparticles.

Language: Английский

Citations

34

Metal-Based Nanoparticles as Antimicrobial Agents: A Review DOI
Li Luo, Wan Huang, Jun Zhang

et al.

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: 7(3), P. 2529 - 2545

Published: Jan. 18, 2024

Antibiotic abuse has become a rising public health concern in recent years, leading to dangerous bacteria developing antibiotic resistance most medicines currently use. Traditional antimicrobial medications have been helpful the early stages of treating numerous forms serious bacterial infectious diseases; however, despite significant therapeutic benefit, there are number issues with follow-up treatment. Metal-based nanomaterials, which properties including difficulty establishing drug and advantages reduced cytotoxicity, considered promising substances. This review discusses important types metal-based nanoparticles (MNPs), such as copper, titanium, zinc oxide, etc., focus on applications gold- silver-based nanoparticles. Furthermore, advanced research progress MNPs agents stimuli-responsive metal nanoparticle strategies working under photothermal, magnetic, pH stimulation also summarized this article. In general, advancement technology, materials based will offer excellent prospects for improving applications.

Language: Английский

Citations

34

Design and Nanoengineering of Photoactive Antimicrobials for Bioapplications: from Fundamentals to Advanced Strategies DOI

Huilong Xin,

Yuanyuan Liu, Yinan Xiao

et al.

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: 34(38)

Published: April 23, 2024

Abstract Currently, microbial infections have posed an arduous challenge to global public health, whereas the rise of antibiotic resistance is rendering traditional therapies futile, prompting development new antimicrobial technologies. Photoactive nanomaterials thus garnered a thriving interest for disinfection owing their superior antibacterial efficaciousness, favorable biosafety, and rapidness spatiotemporal precision in excreting bactericidal actions. The review summarizes recent advances emerging trends design, nanoengineering, bioapplications photoactive antimicrobials. It commences by elaborating fundamental theories on bacterial resistance, mechanisms phototherapy. Subsequently, regulation effectiveness comprehensively discussed, centering criteria strategies tuning photoabsorption spectra, photothermal conversion, photocatalytic efficiency, alongside tactics enabling synergistic therapies. This followed comparative analyses techniques modalities synthesizing engineering with diverse structures, forms, functionalities. Thereafter, state‐of‐the‐art applications phototherapies across various medical sectors are portrayed, key challenges opportunities finally discussed spur future innovations translation. envisaged provide useful guidance devising developing nanomaterials‐based photoresponsive antimicrobials application‐specific materials properties biological functions.

Language: Английский

Citations

33