Polymers,
Journal Year:
2024,
Volume and Issue:
16(13), P. 1795 - 1795
Published: June 25, 2024
A
novel
self-gelatinizing
powder
was
designed
to
accelerate
wound
healing
through
enhanced
hemostasis
and
tissue
recovery.
Significantly,
this
research
addresses
the
critical
need
for
innovative
management
solutions
by
presenting
a
approach.
Carboxymethylcellulose
calcium
(CMC-Ca)
synthesized
using
an
ion
exchange
method,
lysine
(Lys)
integrated
physical
mixing
augment
material’s
functional
characteristics.
The
prepared
underwent
comprehensive
evaluation
its
self-gelling
capacity,
gelation
time,
adhesion,
swelling
rate,
coagulation
efficiency,
hemostatic
effectiveness,
promotion.
Results
indicate
that
exhibited
remarkable
water
absorption
capabilities,
absorbing
liquid
up
30
times
weight
achieving
rapid
within
3
min.
inclusion
of
Lys
notably
powder’s
gel-forming
properties.
time
determined
be
4
s
rotational
rheometer,
with
rapidly
forming
stable
gel
on
skin
surface.
Furthermore,
in
mouse
injury
model,
near-complete
recovery
observed
14
days,
underscoring
impressive
self-healing
attributes
promising
application
prospects
management.
Journal of Tissue Engineering,
Journal Year:
2023,
Volume and Issue:
14
Published: Jan. 1, 2023
Scars
caused
by
skin
injuries
after
burns,
wounds,
abrasions
and
operations
have
serious
physical
psychological
effects
on
patients.
In
recent
years,
the
research
of
scar
free
wound
repair
has
been
greatly
expanded.
However,
understanding
complex
mechanisms
healing,
in
which
various
cells,
cytokines
mechanical
force
interact,
is
critical
to
developing
a
treatment
that
can
achieve
scarless
healing.
Therefore,
this
paper
reviews
types
mechanism
formation
healing
process,
current
progress
dual
consideration
prevention,
some
strategies
for
repair.
Advanced Healthcare Materials,
Journal Year:
2024,
Volume and Issue:
13(22)
Published: May 27, 2024
Infected
wounds
pose
challenges
such
as
exudate
management,
bacterial
infections,
and
persistent
inflammation,
making
them
a
significant
challenge
for
modern
dressings.
To
address
these
issues
in
infected
more
effectively,
aerogel-hydrogel
biphase
gels
based
on
dextran
are
developed.
The
gel
introduced
this
study
exhibits
antibacterial
anti-inflammatory
properties
the
process
of
wound
therapy,
contributing
to
accelerated
healing.
aerogel
phase
exceptional
water-absorption
capabilities,
rapidly
soaking
up
from
wound,
thereby
fostering
clean
hygienic
healing
microenvironment.
Concurrently,
is
enriched
with
hydrogen
sulfide
donors.
Following
water
absorption
formation
hydrogel
phase,
it
enables
sustained
release
around
sites.
experiments
confirm
that
sulfide,
by
promoting
M2
macrophage
differentiation
reducing
levels
inflammatory
factors,
effectively
diminishes
local
inflammation
at
site.
Furthermore,
sodium
copper
chlorophyllin
component
within
demonstrates
effective
through
photodynamic
antimicrobial
providing
viable
solution
infection
challenges.
Advanced NanoBiomed Research,
Journal Year:
2024,
Volume and Issue:
4(5)
Published: Feb. 22, 2024
Skin
injuries
pose
significant
health
challenges,
with
conditions
like
burns
and
diabetic,
venous,
pressure
ulcers
presenting
complex
wound
management
scenarios.
Effective
care
strategies
for
these
encompass
a
range
of
interventions,
from
simple
dressings
to
bioactive
materials
surgical
procedures
involving
skin
substitutes
grafting.
This
review
explores
the
potential
natural
polymers,
including
silk,
collagen,
gelatin,
elastin,
cellulose,
chitosan,
alginate,
hyaluronic
acid,
in
management.
Natural
polymers
offer
several
advantages,
abundance,
biodegradability,
compatibility
traditional
modern
material
fabrication
techniques,
have
demonstrated
safety
efficacy
clinical
applications,
modulating
various
facets
healing
process.
Highlighting
preclinical
studies,
along
commercial
products,
this
showcases
versatility
utility
provides
insights
into
emerging
developments,
such
as
3D
bioprinting
stimuli‐responsive
materials,
which
hold
promise
personalized
treatments.
Additionally,
we
discuss
importance
format
morphology
engineering
next
generation
substitutes,
offering
pathway
optimize
enhanced
outcomes.
Advanced Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 28, 2025
Abstract
Ionic
conductive
hydrogels
(ICHs)
are
emerging
as
key
materials
for
advanced
human‐machine
interactions
and
health
monitoring
systems
due
to
their
unique
combination
of
flexibility,
biocompatibility,
electrical
conductivity.
However,
a
major
challenge
remains
in
developing
ICHs
that
simultaneously
exhibit
high
ionic
conductivity,
self‐healing,
strong
adhesion,
particularly
under
extreme
low‐temperature
conditions.
In
this
study,
novel
ICH
composed
sulfobetaine
methacrylate,
methacrylic
acid,
TEMPO‐oxidized
cellulose
nanofibers,
sodium
alginate,
lithium
chloride
is
presented.
The
hydrogel
designed
with
hydrogen‐bonded
chemically
crosslinked
network,
achieving
excellent
conductivity
(0.49
±
0.05
S
m
−1
),
adhesion
(36.73
2.28
kPa),
self‐healing
capacity
even
at
−80
°C.
Furthermore,
the
maintain
functionality
over
45
days,
showcasing
outstanding
anti‐freezing
properties.
This
material
demonstrates
significant
potential
non‐invasive,
continuous
monitoring,
adhering
conformally
skin
without
signal
crosstalk,
enabling
real‐time,
high‐fidelity
transmission
cryogenic
These
offer
transformative
next
generation
multimodal
sensors,
broadening
application
possibilities
harsh
environments,
including
weather
outer
space.
